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Preparation technology and application of non-decocted preparation containing animal bone and shell type traditional Chinese medical materials

A preparation process and animal bone technology, applied in the direction of reptile medical raw materials, pharmaceutical formulas, unknown raw materials, etc., can solve problems such as waste of energy, diminished drug efficacy, poor flexibility, etc., to achieve simple process control and reduced damage Small, the effect of improving extraction efficiency

Inactive Publication Date: 2015-12-23
HENAN XINGZHI PATENT SERVICE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although where conditions permit, some hospitals and outpatient clinics have finished compound decoction products in stock, which can be consumed only by heating. However, the curative effect of each pair of compound decoction finished products is fixed, and it cannot be mixed on site according to the condition, so it is relatively flexible. Poor, storing the finished compound decoction at the same time, there are problems such as occupying space and wasting energy, and the efficacy of the finished compound decoction will gradually decrease during the storage process
Even if the extract and other Chinese medicinal materials are prepared into a compound preparation, its application range will be limited due to the fixed formula and definite curative effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Taking turtle shell as an example, the preparation method of Chinese medicine decoction-free preparation is carried out according to the following steps:

[0037] 1) Rinse the turtle shell with running water, shake it quickly and drain it. After passing the inspection, put it in boiling water and boil it for 6 minutes to remove the fishy smell and heat the inside. Take it out quickly and put it into edible vinegar, let it cool, take it out, and dry it ; Manually clean the unqualified medicinal materials to remove impurities and turbidity visible to the naked eye;

[0038] 2) The turtle shells treated in step 1) are coarsely powdered in turn, passed through a 18-mesh sieve, and then the coarse powder and water are placed in a container at a weight ratio of 1:2, vacuum-sealed and subjected to ultra-high pressure treatment to maintain a pressure of 100 MPa, keep for 28 minutes, crisp the turtle shell, dry, carry out secondary crushing, and pass through a 100-mesh sieve to ...

Embodiment 2

[0042] Taking turtle shell as an example, the preparation method of Chinese medicine decoction-free preparation is carried out according to the following steps:

[0043] 1) Rinse the turtle shell with running water, shake it quickly and drain it. After passing the inspection, put it in boiling water and boil it for 5 minutes to remove the fishy smell and heat the inside. Take it out quickly and put it in edible vinegar, let it cool, take it out, and dry it ; Manually clean the unqualified medicinal materials to remove impurities and turbidity visible to the naked eye;

[0044] 2) The turtle shells treated in step 1) are subjected to coarse powder in turn, passed through a 18-mesh sieve, and then the coarse powder and water are placed in a container at a weight ratio of 1:2.5, vacuum-sealed and subjected to ultra-high pressure treatment to maintain a pressure of 180 MPa, maintained for 20 minutes, crisped the turtle shell, dried, carried out secondary crushing, and passed throu...

Embodiment 3

[0048] Taking shark bone as an example, the preparation method of Chinese medicine decoction-free preparation is carried out according to the following steps:

[0049] 1) Rinse the shark bone with running water, shake it quickly and drain it. After passing the inspection, put it in boiling water and boil for 8 minutes to remove the fishy smell and heat the inside. Take it out quickly and put it in vinegar, let it cool, take it out, and dry it ; Manually clean the unqualified medicinal materials to remove impurities and turbidity visible to the naked eye;

[0050] 2) Shark bones treated in step 1) are subjected to coarse powder in turn, passed through a 20-mesh sieve, and then the coarse powder and water are placed in a container at a weight ratio of 1:3, vacuum-sealed and subjected to ultra-high pressure treatment to maintain a pressure of 350 MPa, keep 25 minutes, make the shark bone crisp, dry, carry out secondary pulverization, cross 120 mesh sieves, obtain the shark bone p...

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PUM

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Abstract

The invention provides a preparation technology and an application of a non-decocted preparation containing animal bone and shell type traditional Chinese medical materials and belongs to the technical field of traditional Chinese medicine preparation. The preparation technology of the non-decocted preparation containing the animal bone and shell type traditional Chinese medical materials comprises steps as follows: firstly, the animal bone and shell type traditional Chinese medical materials are washed with flowing water and subjected to oscillation draining, the materials passing inspection are boiled and heated for short time, then fished out rapidly and put into table vinegar, and the cooled materials are taken out and dried; then the materials are subjected to coarse grinding, stewing, drying and secondary grinding, and animal bone and shell type traditional Chinese medical material powder is obtained; the animal bone and shell type traditional Chinese medical material powder is subjected to ethanol extraction and ultrasonic strengthening processing simultaneously, then ethanol is recycled through reduced pressure concentration, and animal bone and shell type traditional Chinese medical material extract is obtained; the animal bone and shell type traditional Chinese medical material extract is subjected to spray drying and passes a screen with more than 200 meshes, powder is obtained and subjected to sterilization and vacuum packaging, and a finished product is obtained. The preparation technology is simple to control, green and environment-friendly, synergistic interaction of all technological steps is realized, so that the universality of a preparation method is higher, the extraction efficiency is higher, active ingredients are effectively protected, and the availability of the finished product of the animal bone and shell type traditional Chinese medical materials is better improved.

Description

technical field [0001] The invention belongs to the technical field of preparation of traditional Chinese medicines, and in particular relates to a preparation process and an application of a non-decoction-free preparation of Chinese medicinal materials such as animal bones. Background technique [0002] Traditional Chinese medicine is the crystallization of the wisdom of the Chinese nation and has made great contributions to the protection of people's health. The traditional dosage forms of traditional Chinese medicine include pills, powders, ointments, liquors, etc., but most of the traditional dosage forms have shortcomings such as large dosage, thick dosage form, and poor appearance. The pace of development, the introduction of high technology, and the use of new technologies to improve the quality of traditional Chinese medicine are one of the important ways to reform the formulation of traditional Chinese medicine. [0003] Animal bones and Chinese herbal medicines su...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/32A61K35/586A61K35/60A61K35/58
Inventor 马新攀
Owner HENAN XINGZHI PATENT SERVICE CO LTD