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Medicinal absorbable suture and preparation method

A technology of suture and carboxymethyl chitosan, applied in the field of medical materials, can solve the problems of inability to meet various medical needs at the same time, poor biocompatibility, unsatisfactory absorption effect, etc., and achieve good biodegradability , The effect of promoting wound healing and shortening the treatment time

Inactive Publication Date: 2016-02-03
钊桂英
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the use of medical absorbable sutures is mainly catgut and chemically synthesized sutures, which are easy to affect the absorption process due to individual differences in patients, and the absorption effect is not ideal, and even the phenomenon of non-absorption occurs, which has the disadvantage of rejection. Increased patient pain; existing absorbable sutures have low tensile strength and poor biocompatibility
At present, the function of the existing suture is relatively single, and it cannot meet the various needs of medical use at the same time.

Method used

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  • Medicinal absorbable suture and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Example 1 A medical absorbable suture thread prepared from the following main raw materials in parts by weight (180g each): 20 parts of polyhydroxybutyrate (PHB), 55 parts of carboxymethyl chitosan, and Eclipta prostrata 5 Servings, 3 scuttlefish, 8 Guanzhong, 7 peony roots, 5 alum, 4 pomegranate rind, 3 agrimony, 6 cistanche, 4 magnolia, 3 eucommia, 4 salvation Servings, 6 servings of purple beads, 3 servings of Morus sylvestris, appropriate amount of glycerin.

[0036] The preparation method of the above medical absorbable suture thread is:

[0037] (1) Put the Eclipta indica into the pot, add vinegar and stir fry. Add vinegar every 4 minutes. The amount of vinegar added each time is 8% of the weight of Eclipta indica. Add vinegar 4 times in total. Continue after adding vinegar Stir-fry for 12 minutes, remove, let cool, and set aside;

[0038] (2) Scrub the cuttlefish, dry it, smash it into small pieces, put it in a pot, fry it with a slow fire until it is yellow, take it ...

Embodiment 2

[0042] Example 2 A medical absorbable suture thread prepared from the following main raw materials in parts by weight (180g each): 32 parts of polyhydroxybutyrate (PHB), 74 parts of carboxymethyl chitosan, Eclipta prostrata 9 Parts, 6 parts of cuttlefish, 12 parts of Guanzhong, 10 parts of white peony root, 10 parts of dry alum, 8 parts of pomegranate peel, 5 parts of agrimony, 10 parts of Cistanche, 9 parts of Magnolia officinalis, 6 parts of Eucommia, 10 parts of Jiu Bing Servings, 11 servings of Zizhu, 7 servings of Morus sylvestris, appropriate amount of glycerin.

[0043] The preparation method of the above medical absorbable suture thread is:

[0044] (1) Put the Eclipta indica into the pot, add vinegar and stir fry. Add vinegar every 4 minutes. The amount of vinegar added is 18% of the weight of Eclipta indica. Add vinegar 4 times in total. Continue after adding vinegar. Stir-fry for 12 minutes, remove, let cool, and set aside;

[0045] (2) Scrub the cuttlefish, dry it, sma...

Embodiment 3

[0050] Example 3 A medical absorbable suture thread prepared from the following main raw materials in parts by weight (180g each): 23 parts of polyhydroxybutyrate (PHB), 58 parts of carboxymethyl chitosan, Eclipta prostrata 6 Servings, 4 scuttlefish, 9 Guanzhong, 8 peony roots, 7 alum, 5 pomegranate peels, 3.5 agrimony, 7 cistanche, 5 magnolia, 4 eucommia, 6 Jiu Bing Servings, 7 servings of Zizhu, 4 servings of Morus sylvestris, appropriate amount of glycerin.

[0051] The preparation method of the above medical absorbable suture thread is:

[0052] (1) Put the Eclipta indica into the pot, add vinegar and stir fry, add vinegar every 4 minutes, the amount of vinegar added each time is 10% of the weight of Eclipta indica, add vinegar 4 times in total, continue after adding vinegar Stir-fry for 12 minutes, remove, let cool, and set aside;

[0053] (2) Scrub the cuttlefish, dry it, smash it into small pieces, put it in a pot, fry it with a slow fire until it is yellow, take it out, an...

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PUM

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Abstract

The invention discloses a medicinal absorbable suture and a preparation method thereof. The medicinal absorbable suture has the good functions of stopping bleeding and pains, restraining bacteria and promoting wound healing. The medicinal absorbable suture is mainly prepared from, by weight, 20-32 parts of PHB, 55-74 parts of carboxymethyl chitosan, 5-9 parts of eclipta prostrate, 3-6 parts of cuttlebones, 8-12 parts of cyrtomium fortunei, 7-10 parts of white peony roots, 5-10 parts of dried alums, 4-8 parts of pomegranate peels, 3-5 parts of hairyvein agrimony, 6-10 parts of desertliving cistanche, 4-9 parts of mangnolia officinalis, 3-6 parts of eucommia ulmoides, 4-10 parts of ovate leaf holly bark, 6-11 parts of bodinier's beauty-berries, 3-7 parts of taxillus chinensis and an appropriate amount of glycerin. The obtained product is safe to use, free of toxic and side effects and stimulation and appropriate in strength and flexibility, the surface friction coefficient is small, suturing and knotting are easy, and the suture has good biodegradability, can be completely absorbed by bodies, has no obvious individual difference, has good biocompatibility, and can shorten treatment time, avoid wound infection and promote wound healing.

Description

technical field [0001] The invention belongs to the field of medical materials, and in particular relates to a medical absorbable suture and its preparation method. Background technique [0002] Medical suture is a common thread material, which is widely used in various surgical operations to suture wounds and connect tissues. Absorbable suture: In surgical suture, after being implanted in human tissue, it can be degraded and absorbed by the human body, and it does not need to be removed, but it is a new type of suture material that avoids the pain of removing the stitches. According to the absorbability of the suture material, it can be divided into catgut, chemically synthesized polymer thread, and pure natural collagen suture. Requirements for medical sutures: 1. It can maintain sufficient strength during wound healing, and should be able to stretch to adapt to wound edema, and retract to its original length as the wound retracts. 2. After the wound is healed, it can be...

Claims

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Application Information

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IPC IPC(8): A61L17/10A61L17/06A61L17/08
Inventor 不公告发明人
Owner 钊桂英
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