A kind of preparation method of chlorogenic acid-gelatin film food preservative
A technology of chlorogenic acid and antistaling agent, which is applied in the field of preparation of chlorogenic acid-gelatin film-coated food preservative, can solve the problems of poor water solubility, etc., and achieve the goal of overcoming poor water solubility, preventing the invasion of exogenous microorganisms, and prolonging the shelf life of food Effect
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Embodiment 1
[0017] 1. Dissolve 1mmol of chlorogenic acid in 20mL of 0.1M citrate buffer (pH5.5). 2mmol EDC (1-(3-dimethylaminopropyl)-3-ethylcarbodiimide salt) and 2mmol NHS (N-hydroxysuccinimide) were added, and the reaction was stirred with magnetic force at room temperature for 15min. Adjust the pH of the solution with a concentration of 0.2M phosphate buffer (pH7.4) to make pH>7.
[0018] 2. Heat and dissolve 0.088g of gelatin in 5mL of 0.2M phosphate buffer (pH7.4) in a water bath at 50°C. Then the dissolved gelatin was added into the reaction solution, and the reactants were stirred and reacted at room temperature for 24 hours.
[0019] 3. Put the obtained reaction product into a dialysis bag, dialyze in ultrapure water for 3.5 days, and change the water every 3 hours.
[0020] 4. The finished product of dialysis is subjected to freeze-drying treatment, and the obtained freeze-dried substance is chlorogenic acid-gelatin-coated food preservative.
[0021] The chlorogenic acid can ...
Embodiment 2
[0024] 1. Dissolve 1mmol of chlorogenic acid in 20mL of 0.1M citrate buffer (pH5.5). Add 2mmol EDC (1-(3-dimethylaminopropyl)-3-ethylcarbodiimide salt) and 2mmol NHS (N-hydroxysuccinimide), and stir the reaction at room temperature for 15min. Adjust the pH of the solution with a concentration of 0.2M phosphate buffer (pH7.4) to make pH>7.
[0025] 2. Heat and dissolve 0.177g of gelatin in 5mL of 0.2M phosphate buffer (pH7.4) in a water bath at 50°C. Then the dissolved gelatin was added into the reaction solution, and the reactants were stirred and reacted at room temperature for 24 hours.
[0026] 3. Put the obtained reaction product into a dialysis bag, dialyze in ultrapure water for 3.5 days, and change the water every 3 hours.
[0027] 4. The finished product of dialysis is subjected to freeze-drying treatment, and the obtained freeze-dried substance is chlorogenic acid-gelatin-coated food preservative.
[0028] According to infrared spectrum and nuclear magnetic resonan...
Embodiment 3
[0030] 1. Dissolve 1mmol of chlorogenic acid in 20mL of 0.1M citrate buffer (pH5.5). 2mmol EDC (1-(3-dimethylaminopropyl)-3-ethylcarbodiimide salt) and 2mmol NHS (N-hydroxysuccinimide) were added, and the reaction was stirred with magnetic force at room temperature for 15min. Adjust the pH of the solution with a concentration of 0.2M phosphate buffer (pH7.4) to make pH>7.
[0031] 2. Dissolve 0.354g of gelatin with 5mL of 0.2M phosphate buffer solution (pH7.4) in a 50°C water bath. Then the dissolved gelatin was added into the reaction solution, and the reactants were stirred and reacted at room temperature for 24 hours.
[0032] 3. Put the obtained reaction product into a dialysis bag, dialyze in ultrapure water for 3.5 days, and change the water every 3 hours.
[0033] 4. The finished product of dialysis is subjected to freeze-drying treatment, and the obtained freeze-dried substance is chlorogenic acid-gelatin-coated food preservative.
[0034] According to the identific...
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