Ion mobility spectrometry mobility axis correction method and ion mobility spectrometry mobility axis correction instrument
An ion mobility spectrometer and ion technology, which is applied in the field of ion mobility spectrometry migration axis calibration and instruments, can solve the problems of reducing the signal amplitude of the target object or consistent drift time, and damaging the ability to detect the target object, so as to improve the identification rate and improve The effect of correcting or measuring, improving accuracy
Active Publication Date: 2016-02-24
BRUKER OPTICS GMBH & CO KG
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[0013] International patent application WO2010 / 051241A1 suggests that calibrators and reactants used in conventional ion mobility spectrometers may impair their ability to detect target species, such as reduced signal amplitude or consistent drift times
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[0037] The embodiments of the present invention are described in detail below only by way of example, with reference to the accompanying drawings. It should be noted that the following drawings are schematic diagrams and are not drawn to scale. The relative size and proportions of parts of the pictures may be scaled for illustration and convenience. In the drawings, the same reference characters are used to indicate corresponding or similar parts in modified and different embodiments.
[0038] figure 2 An ion mobility spectrometer 2 is shown, which includes an ionization source 10, a mobility analyzer 20, a calibrant pool 30 and an air pump 40. Ion source 10 comprising a first ionization region 11a, a second ionization region 11b and a third region 11c, wherein ionization regions 11a and 11b contain radiation sources 12a and 12b and are in fluid communication with third region 11c. The ionization regions 11a and 11b are separated from the third region by Bradbury-Nielson g...
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The present invention relates to a method and an instrument for correcting ion mobility spectrometry mobility axis and determining ion mobility spectrometry ion variety mobility characteristics, particularly correcting the drift time axis of the ion mobility spectrometry acquired by a drift type ion mobility spectrometer (IMS). The invention provides an ion mobility spectrometer, which is characterized in that the ion mobility spectrometer is an ion source, which comprises a first ionization region forming a fluid communication with a sample source, a second ionization region isolated from the first ionization region in the space and forming a fluid communication with a calibrator pool, and an electrical measure for controlling sample ions to be conveyed into the second ionization region from the first region or controlling sample ions to enter the third region of the ion source, wherein the third region forms fluid communications with the first ionization region and the second ionization region, and the distance between the third region and a mobility analyzer is closer than the distance between the first ionization region and the mobility analyzer and the distance between the second ionization region and the mobility analyzer.
Description
technical field [0001] The invention relates to a method and an instrument for correcting the migration axis of the ion mobility spectrum and measuring the ion species migration characteristics of the ion mobility spectrum, especially for correcting the drift time axis of the ion mobility spectrum collected by a drift ion mobility spectrometer (IMS). Background technique [0002] Ion mobility spectrometry is used to characterize chemical substances based on the gas phase mobility of different ion species under electromagnetic influence. It has been used as an analytical technique since the late 1960s and early 1970s. The ion mobility spectrometer (IMS) operating at room temperature has high sensitivity to the detection of low-concentration substances in the atmosphere and from gasification samples, and has been successfully applied in the civilian field to detect environmental pollutants, explosives, and illegal drugs in the civilian field, as well as Military field detecti...
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Login to View More IPC IPC(8): G01N27/62G01N27/622
Inventor 安德雷亚斯·拜勒迈克尔·布拉施克
Owner BRUKER OPTICS GMBH & CO KG