Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Nanoparticle targeted delivery method based on sound field control

A nanoparticle and sound field technology, applied in the field of sound manipulation, can solve the problems of sound field manipulation in difficult medical ultrasonic frequency bands

Inactive Publication Date: 2016-05-04
SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
View PDF5 Cites 11 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since the size of nanoparticles is much smaller than the wavelength, and they are affected by the Brownian motion and the viscosity of the solution, it is difficult to be manipulated by the sound field of the medical ultrasound band.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Nanoparticle targeted delivery method based on sound field control
  • Nanoparticle targeted delivery method based on sound field control
  • Nanoparticle targeted delivery method based on sound field control

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0029] Such as figure 1 , figure 2 As shown, the nanoparticle targeted delivery method based on sound field manipulation of the present application, an embodiment thereof, comprises the following steps:

[0030] Step 102: Build a sound field and a control system, the sound field includes a chamber, and the control system includes an ultrasonic emission device.

[0031] In one embodiment, the chamber comprises a laboratory chamber, a human environment or an animal environment. Wherein, the experimental chamber includes a bottom plate 12 , a side wall 13 and a cover plate 14 , the side wall 13 is arranged on the bottom plate 12 , the cover plate 14 is covered on the side wall 13 , and the side wall 13 encloses a cylindrical cavity 14 . The bottom plate can be made of silicon wafer, the side wall 13 can be made of adhesive tape, and the cover plate 15 can be made of cover glass. Wherein the side wall 13 and the cavity 14 can specifically be made by punching holes in the middl...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a nanoparticle targeted delivery method based on sound field control; the method includes the steps: building a sound field and a control system, wherein the sound field includes a chamber, and the control system comprises an ultrasonic emitting device; preparing hollow porous nanoparticles; and putting the nanoparticles into the chamber, making the ultrasonic emitting device emit ultrasonic waves, regulating the sound field to control the movement of the nanoparticles, and making the nanoparticles delivered in a targeted manner. In the embodiment, the hollow porous nanoparticles are put into the chamber, the ultrasonic emitting device is allowed to emit the ultrasonic waves, the sound field is regulated to control the movement of the nanoparticles, and the nanoparticles are delivered in the targeted manner; with combination of the sound field action and the special structure of the nanoparticles, the nanoparticles with the three-dimensional scale of nano scale can be controlled and can be used for targeted delivery of drugs.

Description

technical field [0001] The present application relates to acoustic manipulation technology, in particular to a nanoparticle targeted delivery method based on acoustic field manipulation. Background technique [0002] Acoustic manipulation is mainly to use the particles in the sound field to be subjected to the sound radiation force, the drag force or shear force caused by the sound flow, etc. to realize the functions of capturing, arranging, moving, rotating and releasing the particles. Since ultrasound has been widely used in clinical imaging detection, and it has been proven that low-intensity ultrasound will not cause significant damage to the body, ultrasonic manipulation of particles is a non-contact, non-invasive, and convenient manipulation method. Therefore, the targeted delivery of nano-drug carriers based on this technology is of great significance and practical application value for the precise treatment of major diseases such as tumors. [0003] In the prior art...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K41/00A61K47/32A61K49/22A61P35/00
CPCA61K41/0047A61K47/32A61K49/228
Inventor 陈冕郑海荣王志勇刘新蔡飞燕孟龙严飞李飞王辰
Owner SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com