Medicine composition for treating depression and preparation method thereof

A composition and technology for depression, which can be used in drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., and can solve the problems of complex etiology of depression, imbalance of neurotransmitters in depression, etc.

Inactive Publication Date: 2016-05-11
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The etiology of depression is complex, and the research on its pathogenesis has not yet reached a consistent conclusion. Some studies believe that depression is related to the imbalance of neurotransmitters in the body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1: the pharmaceutical composition for the treatment of depression and its preparation method

[0036]The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating depression are: 2150g chrysanthemum japonica, 2045g sophorinoside, 123g hollyhock seeds, 865g lycyrrhizin C35g;

[0037] Preparation:

[0038] (1) According to the ratio of the raw materials, take the chrysanthemum mustard, brucea japonica, sophorin, marshmallow seed, and liquiritigenin C, mix them evenly, use ethanol with a concentration of 30.5% by weight as a solvent, and extract by warm soaking at 50°C. The number of extractions is 18 times, each extraction time is 1.6 hours, and the amount of solvent used each time is 23.5 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A recovers ethanol, and concentrates to a relative density of 1.10 , filtered, the liquid medicine passes through the ...

Embodiment 2

[0041] Embodiment 2: the pharmaceutical composition for the treatment of depression and its preparation method

[0042] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating depression are: 2120g of chrysanthemum japonica, 2060g of sophorinoside, 120g of marshmallow seed, 870g of lilycyrrhizin C32g;

[0043] Preparation:

[0044] (1) According to the ratio of the raw materials, take the chrysanthemum mustard, brucea japonica, sophorin, marshmallow seed, and liquiritigenin C, mix them evenly, use ethanol with a concentration of 30.5% by weight as a solvent, and extract by warm soaking at 50°C. The number of extractions is 18 times, each extraction time is 1.6 hours, and the amount of solvent used each time is 23.5 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A recovers ethanol, and concentrates to a relative density of 1.10 , filtered, the liquid medicine pas...

Embodiment 3

[0047] Embodiment 3: the pharmaceutical composition for the treatment of depression and its preparation method

[0048] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating depression are: 2180g of chrysanthemum japonica, 2030g of sophorinoside, 126g of hollyhock seed, 860g of lilycyrrhizin C38g;

[0049] Preparation:

[0050] (1) According to the ratio of the raw materials, take the chrysanthemum mustard, brucea japonica, sophorin, marshmallow seed, and liquiritigenin C, mix them evenly, use ethanol with a concentration of 30.5% by weight as a solvent, and extract by warm soaking at 50°C. The number of extractions is 18 times, each extraction time is 1.6 hours, and the amount of solvent used each time is 23.5 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A recovers ethanol, and concentrates to a relative density of 1.10 , filtered, the liquid medicine passe...

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Abstract

The invention discloses a medicine composition for treating depression and a preparation method thereof. The medicine composition is prepared from neotorularia humilis, sophoricoside, abelmoschus manihot seeds and glepidotin C, can be prepared into various dosage forms according to a conventional preparation process and has a remarkable treatment effect on treating depression.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a pharmaceutical composition for treating depression and a preparation method thereof. Background technique [0002] Depression is a common mental disorder in my country. The patient's persistent low mood is often accompanied by anxiety, physical discomfort and sleep disturbance. It is usually hidden and difficult to be detected. Clinical manifestations have different forms and different depths, ranging from mild depression to severe distress and even suicide. At present, antidepressant drug treatment is mainly limited to tricyclic antidepressants and serotonin reuptake inhibitors, such as imipramine, doxepin, amitriptyline, and selet, etc., but these drugs are likely to make patients dependent. And withdrawal syndrome occurs after stopping the drug. [0003] The theory of traditional Chinese medicine believes that anxiety is mainly caused by "weak viscera...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61P25/24A61K31/352A61K31/7048
CPCA61K36/31A61K9/2013A61K9/2054A61K9/4858A61K31/352A61K31/7048A61K36/28A61K36/71A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55
Inventor 不公告发明人
Owner JINAN XINGYI MEDICAL TECH
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