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Water-soluble root canal lubricant and preparation method thereof

A lubricant and water-soluble technology, applied in the field of water-soluble root canal lubricant and its preparation, can solve the problems of difficult rinsing and weak stability of the paste, and achieve the effects of stable product performance, good effect and simple preparation process

Inactive Publication Date: 2016-06-01
ZHEJIANG ZHEBEI PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Carbamide peroxide is a kind of peroxide, its bactericidal effect is clear, its irritation is small, and its disadvantage is its weak stability
[0010] At present, most of the root canal lubricants containing carbamide peroxide on the market are made into pastes. In the actual application of dentists, after the root canal is lubricated, the root canal lubricant needs to be rinsed off, and the paste is difficult to rinse.

Method used

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  • Water-soluble root canal lubricant and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] prescription:

[0059] EDTA30gPolyethylene glycol90g

[0060] Sodium citrate 0.2g cetyl alcohol 0.4g

[0061] Carbomer 15g Carbomer 3g

[0062] Propylene glycol 4g Purified water 5g

[0063] Preparation:

[0064] 1. Weigh the above-mentioned amount of EDTA and carbamide peroxide, and grind them for later use;

[0065] 2. Weigh the above amount of sodium citrate, add the prescribed amount of water, and stir evenly;

[0066] 3. Add the prescribed amount of polyethylene glycol, cetyl alcohol, propylene glycol, and carbomer, and stir well;

[0067] 4. Add the main ingredients EDTA and carbamide peroxide, stir evenly to make a colloid;

[0068] 5. Packaging into disposable syringes.

Embodiment 2

[0070] prescription:

[0071] Sodium EDTA 30g Polyethylene glycol 100g

[0072] Propylene Glycol 4g Cetyl Alcohol 0.4g

[0073] Carbamide peroxide 15g Purified water 5g

[0074] Preparation:

[0075] 1. Weigh the above-mentioned amount of sodium EDTA and carbamide peroxide and grind them finely for later use;

[0076] 2. Add the prescribed amount of water, polyethylene glycol, cetyl alcohol, and propylene glycol, and stir well;

[0077] 3. Add the main ingredients sodium EDTA and carbamide peroxide, stir evenly to make a colloid;

[0078] 4. Packaged into disposable syringes.

Embodiment 3

[0080] prescription:

[0081] EDTA30gPolyethylene glycol110g

[0082] Carbamide peroxide 11g cetyl alcohol 0.4g

[0083] Propylene glycol 7g Purified water 5g

[0084] Preparation:

[0085] 1. Weigh the above-mentioned amount of EDTA and carbamide peroxide, and grind them for later use;

[0086] 2. Add the prescribed amount of water, polyethylene glycol, cetyl alcohol, and propylene glycol, and stir well;

[0087] 3. Add the main ingredients EDTA and carbamide peroxide, stir evenly to make a colloid;

[0088] 4. Packaged into disposable syringes.

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Abstract

The invention relates to a water-soluble root canal lubricant and a preparation method thereof.The lubricant is of a colloidal form and is prepared from EDTA or EDTA sodium, sodium citrate, polyethylene glycol and an excipient.The preparation method of the water-soluble root canal lubricant includes the following steps that 1, an appropriate amount of the EDTA and / or urea peroxide is taken and is finely grinded for standby application; 2, an appropriate amount of the sodium citrate is taken as an acid-base regulator, a formula dosage of water is added, and even stirring is performed; 3, the polyethylene glycol and the excipient are added, and even stirring is performed; 4, the main components EDTA and / or urea peroxide are added, and even stirring is performed to prepare colloid; 5, the colloid is encapsulated in a disposable syringe.The root canal lubricant prepared by means of the preparation method is good in root canal lubricating effect, can kill various germs while performing root canal lubrication and facilitates root canal treatment.A doctor can easily flush off the residual root canal lubricant after using the lubricant.

Description

technical field [0001] The invention belongs to the technical field of medicine and medical devices, and in particular relates to a water-soluble root canal lubricant and a preparation method thereof. Background technique [0002] Root canal therapy (RootCanal Therapy, RCT) is the most common and effective method to treat pulp disease and periapical disease, and it is an important means to preserve teeth. After years of continuous improvement and perfection, root canal therapy has established a relatively complete system, including three major steps of root canal preparation, root canal disinfection and root canal filling. [0003] During the root canal preparation process, a smear layer may be produced. The smear layer covering the root canal wall will affect the penetration of the root canal disinfectant into the dentin tubules, weaken its bactericidal effect, and affect the adhesion of the root canal filling material to the root canal wall. Lead to the failure of root ca...

Claims

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Application Information

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IPC IPC(8): A61K6/00A61L31/06A61L31/00
CPCA61K6/15A61K6/52A61K6/60A61L31/005A61L31/06A61L2400/10C08L71/00
Inventor 王国华郑岭岭汪文洁潘世浩杨迪迪
Owner ZHEJIANG ZHEBEI PHARM CO LTD
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