Polypeptide, and a detection device and a detection kit containing polypeptide

A technology for detection kits and devices, applied in the field of peptides, can solve the problems of inspectors with high skills and inspection requirements, and unable to satisfy patients

Inactive Publication Date: 2016-06-08
SUZHOU INST OF NANO TECH & NANO BIONICS CHINESE ACEDEMY OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, the classic method for diagnosing malaria is still blood smear microscopy, which requires high skills and testing of examin...

Method used

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  • Polypeptide, and a detection device and a detection kit containing polypeptide
  • Polypeptide, and a detection device and a detection kit containing polypeptide
  • Polypeptide, and a detection device and a detection kit containing polypeptide

Examples

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Embodiment

[0066] Hereinafter, the present invention will be described more specifically through examples, but the technical scope of the present invention is not limited. Through the description of this specification, those skilled in the art can easily modify / change the present invention, and these are included in the technical scope of the present invention.

[0067] 1.17 Preparation and Confirmation of Peptides

[0068] The 17 peptide used in the examples has the amino acid sequence shown in SEQ ID NO: 1 and was synthesized by Shanghai Jier Biochemical Co., Ltd. The characterization of the polypeptide can confirm that the polypeptide was synthesized by hydrogen spectrum and mass spectrum. Liquid chromatography detection purity: 95.04% (area normalization method): mass spectrometry detection (ESI-MS): calculated molecular weight: 2128.24, test value 2128.35.

[0069] 2. Fabrication of Detection Devices

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Abstract

The invention relates to a polypeptide, and a detection device and a detection kit containing the polypeptide. The polypeptide provided by the invention is composed of an amino acid sequence as shown in SEQ ID NO: 1. The polypeptide, and the detection device and the detection kit containing the polypeptide provided by the invention are useful in diagnosis of malaria.

Description

technical field [0001] The invention mainly relates to a polypeptide, a detection device and a detection kit containing the polypeptide, and belongs to the field of biotechnology. Background technique [0002] Malaria is an acute infectious disease and the most serious mosquito-borne parasitic disease to humans in the world. The pathogen is Plasmodium, and the symptoms are periodic chills and fever. Due to the complex life cycle of Plasmodium and stage-specific antigens, the prevention and control of malaria has become one of the worldwide problems. Among them, falciparum malaria infects 300-500 million people every year and kills millions of people. In November 2011, according to the latest World Health Organization statistics, there were 216 million malaria cases and 655,000 deaths. Plasmodium is mainly distributed in the tropical and subtropical countries of the earth, namely Africa, Southeast Asia, South America and other regions. About 2 billion people still live in t...

Claims

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Application Information

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IPC IPC(8): C07K14/445C07K16/20C12N15/30C12N15/63G01N33/68
CPCY02A50/30
Inventor 马宏伟卢煜东
Owner SUZHOU INST OF NANO TECH & NANO BIONICS CHINESE ACEDEMY OF SCI
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