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Medicine composition with effects of diminishing inflammation and relieving cough and method for preparing medicine composition

A composition and drug technology, applied in the field of traditional Chinese medicine, can solve problems such as affecting drug efficacy, and achieve the effects of reducing the number of coughs, prolonging the incubation period of coughing, and improving the curative effect.

Inactive Publication Date: 2016-07-06
广西天天乐药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Since the properties of the active components of Chinese medicinal materials are different, if the above-mentioned method is used to distill Huajuhong and bitter almonds with water, the dregs and other medicinal materials are all extracted and ethanolized, and finally the extracts are combined to make an oral liquid. After complete extraction, the drug fails to exert its full effect during use, thus affecting the efficacy of the drug

Method used

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  • Medicine composition with effects of diminishing inflammation and relieving cough and method for preparing medicine composition
  • Medicine composition with effects of diminishing inflammation and relieving cough and method for preparing medicine composition

Examples

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Effect test

Embodiment 1

[0033] Example 1: Scheme 1 Extraction

[0034] 1) Weigh raw materials according to the following quantities: Huajuhong 3kg, Honey-made Baibu 0.3kg, Poria cocos 0.3kg, Zhipinellia 0.3kg, Baiqian 0.5kg, licorice 0.1kg, bitter almond 1kg, Schisandra 0.2kg.

[0035] 2) Distill the orange red and bitter almonds with water steam, collect the distillate, add 10 times the weight of the medicinal material to the 50% ethanol for reflux extraction once, extract for 3 hours, filter, pass the extract through neutral alumina, collect the effluent, and effluent After passing through 732 cationic resin, wash the column with 2 times the weight of the resin, discard the washing solution, continue to elute with 40% ethanol twice the weight of the resin, collect the eluate, continue to pass the eluent through the 717 anion resin, and wash the column with 2 times the weight of the resin Wash the column with water, discard the washing solution, continue to elute with 40% ethanol twice the weight of...

Embodiment 2

[0040]1) Weigh raw materials according to the following quantities: Huajuhong 3kg, Honey-made Baibu 0.3kg, Poria cocos 0.3kg, Zhipinellia 0.3kg, Baiqian 0.5kg, licorice 0.1kg, bitter almond 1kg, Schisandra 0.2kg.

[0041] 2) Distill the orange red and bitter almonds with water steam, collect the distillate, add 8-10 times the weight of medicinal materials to the dregs and 60% ethanol to reflux extract twice, each time for 2 hours, combine the extracts, pass the extracts over neutral alumina, and collect Effluent, the effluent passes through 734 cationic resin, washes the column with water of 2 times the weight of the resin, discards the washing liquid, continues to elute with 60% ethanol twice the weight of the resin, collects the eluate, and continues to pass the eluent through the 711 anion resin, Wash the column with water twice the weight of the resin, discard the washing solution, continue to elute with 60% ethanol twice the weight of the resin, collect the eluate, and con...

Embodiment 3

[0046] 1) Weigh raw materials according to the following quantities: Huajuhong 3kg, Honey-made Baibu 0.3kg, Poria cocos 0.3kg, Zhipinellia 0.3kg, Baiqian 0.5kg, licorice 0.1kg, bitter almond 1kg, Schisandra 0.2kg.

[0047] 2) Distill the orange red and bitter almonds with water steam, collect the distillate, add 8-10 times the weight of medicinal materials to the dregs and 75% ethanol to reflux extract for 3 times, extract for 1 hour each time, combine the extracts, pass the extracts through neutral alumina, Collect the effluent, pass the effluent through D254 cationic resin, wash the column with water twice the weight of the resin, discard the washing solution, continue to elute with 75% ethanol twice the weight of the resin, collect the eluate, and continue to pass the eluent through the D311 anion resin , washed the column with water twice the weight of the resin, discarded the washing solution, continued to elute with 80% ethanol twice the weight of the resin, collected the...

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Abstract

The invention relates to a medicine composition with effects of diminishing inflammation and relieving cough and a method for preparing the medicine composition. The medicine composition comprises, by weight, exocarpium citri grandis, radix stemonae, poria, rhizoma pinelliae, rhizoma cynanchi stauntonii, radix glycyrrhizae, semen armeniacae amarum and fructus schisandrae chinensis. The method for preparing the medicine composition includes distilling the exocarpium citri grandis and the semen armeniacae amarum by the aid of steam; extracting the radix glycyrrhizae and the rhizoma pinelliae by the aid of ethyl alcohol and then extracting the radix glycyrrhizae and the rhizoma pinelliae by the aid of organic solvents; extracting the honey-processed radix stemonae, the honey-processed poria, the honey-processed rhizoma cynanchi stauntonii and the honey-processed fructus schisandrae chinensis by the aid of water; combining extract to obtain the medicine composition. The medicine composition and the method have the advantages that effects of regulating qi-flowing for eliminating phlegm and moistening lungs for relieving the cough can be realized by the medicine composition, and the medicine composition is applicable to the cough, asthma and excessive phlegm due to turbid phlegm obstructing lungs; as observed clinically, definite curative effects are realized by the medicine composition for common cold, bronchitis and faucitis, and toxic and side effects are unfound.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a medicinal composition for reducing inflammation and relieving cough and a preparation method thereof. Background technique [0002] Phlegm turbidity stays in the lungs, obstructing the airway, and the clinical manifestations are cough, wheezing, chest tightness, and excessive phlegm. It is common in cough, wheezing, wheezing, lung distension, lung abscess, and diseases such as bronchitis and pneumonia in Western medicine. There are two internal and external causes of phlegm turbidity obstructing the lungs: internal causes are related to the spleen, such as improper diet, fatigue and spleen damage, or excessive seven emotions, all of which can cause spleen deficiency to fail, unable to raise clear and lower turbidity, resulting in body fluid stopping gathering and becoming Phlegm is turbid and spreads upwards in the lungs, so there is a saying that "the spleen is the...

Claims

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Application Information

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IPC IPC(8): A61K36/904A61P11/14
CPCA61K36/904A61K9/0095A61K9/1652A61K9/2059A61K9/28A61K36/076A61K36/27A61K36/484A61K36/57A61K36/736A61K36/752A61K36/79A61K36/8888A61K47/26A61K2236/331A61K2236/333A61K2236/39A61K2236/55A61K2300/00
Inventor 韦艳红
Owner 广西天天乐药业股份有限公司
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