101results about How to "Inhibition of permeability" patented technology

Compounds, compositions and methods for inhibiting vascular permeability and pathologic angiogenesis by modulating a signaling pathway delineated herein are described. Moreover, methods for producing and screening compounds and compositions capable of modulating the signaling pathway described herein, inhibiting vascular permeability, and inhibiting pathologic angiogenesis are also provided.

Disclosed herein is a thin film type chip device including a coil pattern formed on the substrate; a cavity defining pattern defining a cavity through which a part of the coil pattern is exposed; a filling layer filled in the cavity; and a magnetic layer including a surface layer covering a surface of the filling layer.

A diaphragm for alkaline water electrolysis according to the present invention is provided with a polymeric porous membrane including a polymeric resin and hydrophilic inorganic particles. The porosity of the polymeric porous membrane is at least 30%, but not more than 60%. The average pore size of both surfaces of the polymeric porous membrane is at least 0.5 mu m, but not more than 2.0 mu m. The ratio (mode particle size/average pore size) of the mode particle size of the hydrophilic inorganic particles to the average pore size of the polymeric porous membrane is at least 2.0.

A pipe fitting for rubber hoses, of the type with a thermoplastic substrate, particularly for air conditioning, conditioning and refrigeration systems, particularly for vehicles and the like, comprising a rigid insert which is adapted to be inserted in a hose to be connected, and a bell-shaped element which is adapted to be crimped around the hose, its particularity consisting in that it comprises a double-adhesive solution which is arranged on the outer surface of said rigid insert and is adapted to produce adhesion between said rigid insert and said thermoplastic material of said internal layer of the rubber hose.

The invention relates to a Chinese traditional medicine composition for treating hydrocephalus, cerebral edema and intracranial hypertension which comprises fish encephalolith, raw astragalus root, oriental water plantain rhizome, Poria cocos, plantain seeds, notoginseng, root of red rooted saliva, sweetgum fruit, grassleaved sweetflag rhizome, evodia rutaecarpa, and achyranthes and cyathula root.

The invention provides a preparation method of a malan straw extract, a malan straw product, a pharmaceutical composition and an application thereof. The preparation method comprises the following steps: selecting a right amount of malan straw, crushing into coarse powder or intermediate powder, extracting 2-3 times by decoction in water or by ethanol/petroleum ether refluxing with 1-2 hours for each time, filtering, merging the filtrates, concentrating, and drying to obtain the malan straw extract. The preparation process of the malan straw extract is simple and practicable, and the obtained extract has obvious anti-inflammatory effect and pain-relieving effect and shows good effects for treating hepatitis, gynecologic inflammation, inflammation of urinary system, pneumonia and nephritis diseases, thereby achieving favorable application prospects.

An image display device includes a light source; a power supply section that supplies power to light source; a cooling fan that cools the light source; an input section; a drive section that supplies a voltage to cooling fan; a control section that controls drive section and power supply section. The control section sets a first power value for the output of the power supply section and also a first voltage value for the output of the drive section. The control section measures a time at which the light source has been lighted. If the measured value exceeds a threshold, the control section gradually increases the output of the power supply section up to a second power value that is greater than the first voltage value over a predetermined time.

The present invention relates to chrysanthemum health pillow, and belongs to field of traditional Chinese medicine. Composition in health pillow core is constituted by material medicament by weight percent: chrysanthemum 40%-70%, Ligusticum chuanxiong 15%-30%, peony bark5%-15% and Angelicae dahuricae 5%-15%. The four kinds of medicinal herbs cooperate with each other and strengthens the medicinal power. People will feel clear and freshly by using chrysanthemum pillow regularly which can achieve the aim of reducing blood pressure.

The present invention addresses the treatment of age-related macular degeneration using regulation of pathogenic mechanisms similar to atherosclerosis. In further specific embodiments, compositions that increase reverse cholesterol transport are utilized as therapeutic targets for age-related macular degeneration. In a specific embodiment, the lipid content of the retinal pigment epithelium, and/or Bruch's membrane is reduced by delivering Apolipoprotein A1, particularly a mimetic peptide.

The invention discloses a traditional Chinese medicine preparation, including the traditional Chinese medicine active ingredients and the pharmaceutically acceptable amount of medicinal excipients, the unibract fritillary bulb is smashed into coarse powder, and the unibract fritillary bulb extract liquid is obtained by collecting the percolation liquid and recycling the ethanol according to the percolation methods under the fluid extract and the extract items (appendix IO of Part one of Chinese pharmacopeia 2005 version); the pummelo peel, dried ginger and liquoric root are respectively immersed by ethanol solution and filtered, the filtrate is subject to ethanol recycling and is condensed into thick paste A; the loquat leaf, coastal glehnia root, Indian buead, platycodon root, rhizoma pinelliae preparata, snakegourd fruit and bitter apricot seed are boiled by adding water for 2 to 3 times and 1 to 3 hours for each time, the decoction solution is merged, placed still and filtered, the filtrate is evenly mixed with unibract fritillary bulb extract liquid and the thick paste A, then the menthol ethanol solution and apricot water are added for even mixing, and the medicinal excipients are added to prepare the preparation. The traditional Chinese medicine preparation which is prepared by the invention has the advantages of significant efficacy, high bioavailability, rapid onset of action, convenient administration and easy acceptation by patients, and the invention can be used for the treatment of cough, expectoration or ungratifying expectoration, dry pharynx and mouth and other symptoms.

The invention relates to the field of material preparation, in particular to a preparation method and application of superfine hetian jade powder. The invention provides the preparation method of thesuperfine hetian jade powder; jade is made into jade powder by applying a superfine pulverizing technology, mercury and arsenic which are harmful to human bodies are removed at high temperature, and thus, the jade powder is applied to cosmetics and pharmaceutical preparations. The invention also provides the application of the superfine hetian jade powder in the pharmaceutical preparations; purplejade cream prepared by adding Chinese herbal medicines such as lithospermum root has the effects of eliminating illness, dehumidifying, expelling pus and decay, regenerating tissue, treating scaldingdue to hot water or fire, detoxifying, sterilizing, removing decay and moistening skin.

The invention belongs to the field of daily chemicals, and provides a skin-calming and moisture-preserving presenile-resistant composition. The skin-calming and moisture-preserving presenile-resistantcomposition comprises the following ingredients in percentage by weight: 0.02 to 0.2 percent of dipotassium glycyrrhizinate, 1 to 3 percent of chamomilla recutita flower extracts, 1 to 15 percent ofa presenile-resistant composition, 1 to 20 percent of a humectant, 0.05 to 1 percent of a thickening agent, 0.5 to 2.5 percent of an emulsifying agent, 1 to 10 percent of an emollient and the balancepure water, wherein the presenile-resistant composition is prepared from acetyl hexapeptide-8, bifida ferment lysate, tea extracts, grape seed extracts and blackberry leaf extracts. Through the reasonable compatibility of various ingredients, the composition provided by the invention has the advantages that all ingredients achieve synergistic interaction, so that the free radical elimination efficiency is improved, and the senescence is delayed from a deep layer; the self repair capability of cells is improved; the redness is relieved; the skin barrier is repaired; the damage to the skin caused by various light sources is relieved and restored; and deep water supplementation is provided for the skin to achieve the timely senescence-resistant effect.

The invention relates to the pharmaceutical use of human urinary kallikrein in the treatment of acute coronary artery disease and pharmaceutical composition prepared by the method. Human urinary kallikrein of the invention has an evident therapeutic function for the acute coronary artery disease. In general, it is used by preparing the pharmaceutical composition to freeze dried powder injection and injection liquid.

Shayintongxin tea features that it consists of sea-buckthorn leaf 5-75 wt%, gingko leaf 3-65 wt%, haw 4-50 wt%, ginseng 1-30 wt%, wolfberry fruit 3-40 wt%, and Hangzhou white chrysanthemum 4-50 wt%. It has the obvious feature of multiple target points, i. e., it has the sync effects on four target points of heart, brain, blood vessel and blood.

The invention discloses a soft capsule of traditional Chinese medicine and a preparation method thereof, comprising traditional Chinese medicine active ingredients and pharmaceutical adjuvant with volume can be accepted in medical science. The invention comprises the following processes: American ginseng and tendrilleaf fritillary bulb are crashed into thick powder and mixed evenly; the mixture is percolated according to percolation (appendix IQ of first part in Chinese pharmacopoeia, 2000 version) under the item of liquid extract and extract; alcohol of the percolated liquid is recovered and the percolated liquid turned into thick paste by decompress concentration; pipa leaf, glehnia root, platycodon root, bitter apricot seed and liquorice are boiled in water; the boiled liquid is combined and filtered; the filtered liquid is concentrated into thick paste; the two kinds of thick paste are mixed evenly; menthol and apricot seed water with right amount dissolved by alcohol are added into the mixture and the mixture is mixed evenly; the soft capsule is prepared by adding pharmaceutic adjuvant with volume can be accepted in the medical science into the mixture.The liquid capsule of traditional Chinese medicine prepared by the invention has the advantages of remarkable treatment effect, high degree of biological utilization, fast effect appearance, small poison adverse reaction, convenient medicine taking and easy for patients. So the capsule can be used for treating cases like cough due to yin deficiency, raphe haryngis and pharyngalgia, little sputum but sticky and tongue red and less fur etc.

The present invention relates to a composition comprising a material for inhibiting stem cell factor (SCF) or the receptor thereof for treating or preventing vascular permeability related diseases. Also, the present invention relates to a method for screening for an agent for treating vascular permeability related diseases, comprising the steps of: (a) treating a sample from a patient suspected of having a disease associated with vascular permeability with a candidate material; and (b) comparing the level of expression of the SCF or the receptor thereof with that of a control group. The present invention verifies SCF as a novel target for regulating vascular permeability. When the present invention is used, vascular permeability is decreased in diseases of the eye involving increased vascular permeability, thereby effectively treating or preventing vascular permeability related diseases. Also, vascular permeability can be effectively regulated using the composition. Further, the present invention can be provided as an effective means for screening an agent for treating vascular permeability related diseases by measuring the regulation of the expressions of SCF and c-Kit.

The invention discloses a liver heat-removing and eyesight-improving hawthorn fruit and chrysanthemum flower tea. The tea comprises, by weight, 8-14 parts of golden silk chrysanthemum, 1-3 parts of hawthorn fruits, 2-5 parts of herba taraxaci, 3-5 parts of abalone shell, 1-3 parts of semen cassiae, 2-4 parts of wolfberry fruits, 1-2 parts of mulberry leaves, 1-2 parts of periostracum Cicada, 1-3 parts of honey, 3-6 parts of cucumbers, 5-10 parts of a carrot juice, 3-5 parts of a mulberry fruit juice, 2-8 parts of a dateplum persimmon juice, 10-15 parts of a grape juice and 100-120 pats of mountain spring water. The tea formed by boiling the natural golden silk chrysanthemum, hawthorn fruits and mountain spring water has a delicate mouth feel and a fresh taste, is rich in nutrients, can clear heat and reduce internal heat, is suitable for being drunk in summer, and is popular among people; and the tea contains the herba taraxaci, abalone shell, semen cassiae, wolfberry fruits, mulberryleaves and periostracum cicada, so the tea has the efficacy of clearing heat and detoxifying, removing liver heat and improving eyesight, nourishing the kidney and enriching essence, nourishing bloodand soothing nerves, promoting saliva secretion and quenching thirst, and moistening the lung and relieving cough.

The invention relates to a pharmaceutical composition for treating hemorrhoid and process for preparation, wherein the composition comprises pagodatree fruit 385.5g, red peony root 193g, bark of peony root 193g, ledebouriella root 193g, Chinese angelica root 193g, bitter orange 193g, baikal skullcap root 193g and processed radix aconiti 8g.

The invention provides a medicine for treating burns, which is prepared from pure traditional Chinese medicines, can be used for rapidly scabbing as well as stopping bleeding and alleviating pain, cannot cause scars after healing, ensures that face-lifting and skin grafts are not needed, and does not have side effects. The medicine is characterized by comprising the following traditional Chinese medicine raw materials in parts by weight: 75-85g of root of sinkiang arnebia, 145-155g of coptis chinensis, 105-110g of garden burnet root and 85-95g of medicine terminalia fruit. A preparation method of the medicine comprises the following steps: baking the raw materials, then grinding into powder, screening by using a 180-mesh sieve to obtain fine powder, and mixing the powder in proportions to prepare the medicine.

The invention discloses an anti-alcoholism beverage and a manufacturing method thereof. The anti-alcoholism beverage is prepared from the following raw materials by weight: 5500 to 7500 grams of cress, 2500 to 3500 grams of flos puerariae, 3500 to 4500 grams of hovenia acerba, 420 to 550 grams of roots of kudzu vine, 400 to 580 grams of chrysanthemum, 430 to 600 grams of momordica grosvenori, 450 to 560 grams of sealwort, 450 to 570 grams of tuckahoe, 430 to 540 grams of dandelion, 420 to 530 grams of salisburia adiantifolia (ginkgo), 250 to 340 grams of sweet osmanthus, 260 to 350 grams of mint, 2600 to 3300 grams of honey, 7000 to 8600 grams of glucose and 220 to 280 grams of tartaric acid (food grade). The anti-alcoholism beverage can be drunk instantly at a dinner table or every day and has the beneficial effects of alcoholism prevention, high reaction speed, more comprehensive efficacy and the like, and human health damages of livers, kidneys, lungs and the like of daily drunkards due to alcoholism can be effectively reduced.