Chinese medicinal preparation, preparation and quality control method thereof

A traditional Chinese medicine preparation and technology of traditional Chinese medicine are applied to the traditional Chinese medicine preparation for treating cough, dry throat and mouth, and the fields of expectoration or unpleasant expectoration. , to achieve the effect of improving bioavailability, reducing drug particle size, and taking small doses

Active Publication Date: 2008-07-02
江西药都樟树制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

"Shashen Jugeng Decoction" nourishes the lungs and stomach, promotes body fluid and moistens dryness, treats dryness that hurts the lungs and stomach, body fluid loss, but has poor astringent and cough-relieving effects
The composition of the therapeutic components of the above-mentioned decoction medicine is not fixed, and the dosage of the medicine varies from person to person, and is affected by decoction time, decoction method, etc., so there are many factors affecting the curative effect

Method used

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  • Chinese medicinal preparation, preparation and quality control method thereof
  • Chinese medicinal preparation, preparation and quality control method thereof
  • Chinese medicinal preparation, preparation and quality control method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0107] Active components of traditional Chinese medicine: Fritillaria 50g, Pipa leaves 140g, Radix Ginseng 12g, Poria cocos 35g, Huajuhong 18g, Campanulaceae 70g, Pinellia chinensis 34g, Melon basket 30g, Bitter almond 60g, Ginger 5g, Licorice 28g, Menthol 5g , almond water 18ml;

[0108] Preparation:

[0109] ① Pulverize Fritillaria sichuanensis into coarse powder, according to the percolation method (Chinese Pharmacopoeia 2005 edition one IO) under the extract and extract item, use volume percentage as 90% ethanol solution as solvent, percolate after soaking for 15 hours , until the soluble components are completely drained, the percolation liquid is collected, ethanol is recovered, and the extract of Fritillaria de Chuan is obtained; the rate of percolation is 3ml / min;

[0110] ②The orange red, ginger, and licorice were impregnated with 70% ethanol solution for 20 days respectively, filtered, and the ethanol was recovered from the filtrate, and concentrated into thick oint...

Embodiment 2

[0114] Active components of traditional Chinese medicine: Chuan Fritillaria 65g, Pipa leaves 55g, Adenophora 40g, Poria cocos 26g, Huajuhong 12g, Bellflower 95g, Pinellia 15g, Melon basket 60g, Bitter almond 20g, Ginger 28g, Licorice 15g, Menthol 1.2 g. Almond water 12ml;

[0115] Preparation:

[0116] ① Pulverize Fritillaria sichuanensis into coarse powder, according to the percolation method (Chinese Pharmacopoeia 2005 edition one IO) under the liquid extract and extract item, use volume percentage as 50% ethanol solution as solvent, percolate after 90 hours of immersion , until the soluble components are completely drained, the percolate is collected, ethanol is recovered, and the extract of Fritillaria de Chuan is obtained; the rate of percolation is 1ml / min;

[0117] ②The orange red, ginger, and licorice were impregnated with 95% ethanol solution by volume for 10 days respectively, filtered, and the ethanol was recovered from the filtrate, concentrated into a thick ointm...

Embodiment 3

[0121] Active components of traditional Chinese medicine: Fritillaria 120g, Pipa leaves 80g, Radix Ginseng 34g, Poria cocos 12g, Huajuhong 10g, Bellflower 55g, Pinellia 25g, Melon basket 36g, Bitter almond 70g, Ginger 15g, Licorice 5g, Menthol 2.5g g. Almond water 4ml;

[0122] Preparation:

[0123] ① Pulverize Fritillaria sichuanensis into coarse powder, according to the percolation method (Chinese Pharmacopoeia 2005 edition one IO) under the liquid extract and extract item, use volume percentage as 60% ethanol solution as solvent, percolate after soaking for 20 hours , until the soluble components are completely drained, the percolate is collected, ethanol is recovered, and the extract of Fritillaria de Chuan is obtained; the rate of percolation is 2ml / min;

[0124] ②The orange red, ginger, and licorice were impregnated with 50% ethanol solution by volume percentage for 25 days respectively, filtered, and the filtrate recovered ethanol and concentrated into a thick ointment...

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Abstract

The invention discloses a traditional Chinese medicine preparation, including the traditional Chinese medicine active ingredients and the pharmaceutically acceptable amount of medicinal excipients, the unibract fritillary bulb is smashed into coarse powder, and the unibract fritillary bulb extract liquid is obtained by collecting the percolation liquid and recycling the ethanol according to the percolation methods under the fluid extract and the extract items (appendix IO of Part one of Chinese pharmacopeia 2005 version); the pummelo peel, dried ginger and liquoric root are respectively immersed by ethanol solution and filtered, the filtrate is subject to ethanol recycling and is condensed into thick paste A; the loquat leaf, coastal glehnia root, Indian buead, platycodon root, rhizoma pinelliae preparata, snakegourd fruit and bitter apricot seed are boiled by adding water for 2 to 3 times and 1 to 3 hours for each time, the decoction solution is merged, placed still and filtered, the filtrate is evenly mixed with unibract fritillary bulb extract liquid and the thick paste A, then the menthol ethanol solution and apricot water are added for even mixing, and the medicinal excipients are added to prepare the preparation. The traditional Chinese medicine preparation which is prepared by the invention has the advantages of significant efficacy, high bioavailability, rapid onset of action, convenient administration and easy acceptation by patients, and the invention can be used for the treatment of cough, expectoration or ungratifying expectoration, dry pharynx and mouth and other symptoms.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation for nourishing yin and moistening the lungs, lowering qi and resolving phlegm, in particular to a traditional Chinese medicine preparation for treating cough, expectoration or unpleasant phlegm, dry throat and dry mouth. The invention also relates to the traditional Chinese medicine The preparation method and quality control method of the preparation. Background technique [0002] Cough is a common disease with many causes. Traditional medicine believes that: the lungs govern the release of qi, and the kidneys govern the intake of qi. Chronic illnesses cause cough and asthma. Many, full chest and diaphragm embolism. At present, there are many kinds of cough medicines on the market. Western medicine believes that cough is caused by respiratory tract irritation, such as bacteria, viruses, mycoplasma, mold and other microorganisms, meteorological factors such as sudden climate change, c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/06A61K9/20A61K47/34A61K47/44A61K47/14A61K47/12A61K47/10A61P11/14A61P11/10A61P11/04G01N30/90G01N30/02G01N21/78A61K31/045
Inventor 杨文龙
Owner 江西药都樟树制药有限公司
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