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Preparation method of traditional Chinese medicine composition with functions of treating insomnia, improving senile dementia, enhancing learning and memory abilities, resisting to depression and anxiety and soothing the nerves and benefitting intelligence

A technology for senile dementia and learning and memory ability, which is applied in drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc. Memory ability, wide range of application, improving the effect of Alzheimer's

Inactive Publication Date: 2016-07-13
北京采瑞医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Such traditional Chinese medicine compositions have many components, the quality is not easy to control, the process is not easy to industrialize, and the scope of application is single

Method used

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  • Preparation method of traditional Chinese medicine composition with functions of treating insomnia, improving senile dementia, enhancing learning and memory abilities, resisting to depression and anxiety and soothing the nerves and benefitting intelligence
  • Preparation method of traditional Chinese medicine composition with functions of treating insomnia, improving senile dementia, enhancing learning and memory abilities, resisting to depression and anxiety and soothing the nerves and benefitting intelligence
  • Preparation method of traditional Chinese medicine composition with functions of treating insomnia, improving senile dementia, enhancing learning and memory abilities, resisting to depression and anxiety and soothing the nerves and benefitting intelligence

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Tianma 1kg, Radix Paeoniae Alba 2kg, Acanthopanax 3kg, Jujube Seed 1kg.

[0045] Get above-mentioned crude drug, prepare by following method:

[0046] 1. Take Gastrodia elata, crush it into coarse powder, add 70% ethanol to reflux and extract twice, the amount of alcohol added is 10 and 10 times respectively, for 2 hours each time, recover ethanol under reduced pressure (pressure 0.05MPa, temperature 60°C), and depressurize Concentrate (pressure 0.08MPa, temperature 60°C) into a thick paste (relative density at 60°C is 1.20-1.25), dry under reduced pressure (pressure 0.08Mpa, temperature 70°C) to obtain a dry extract, crush it, and pass through an 80-mesh sieve , to obtain Gastrodia elata extract powder;

[0047] 2. Get Radix Paeoniae Alba, crush it into coarse powder, add 50% ethanol to reflux and extract twice, the amount of alcohol added is 10, 10 times respectively, each time for 1.5 hours, reclaim ethanol under reduced pressure (pressure 0.05MPa, temperature 60 ℃)...

Embodiment 2

[0052] Gastrodia elata 3kg, Radix Paeoniae Alba 7kg, Acanthopanax 9kg, Suanzaoren 3kg.

[0053] Get above-mentioned crude drug, prepare by following method:

[0054] 1. Take gastrodia elata and pulverize it, and pass through an 80-mesh sieve to obtain gastrodia elata fine powder;

[0055] 2. Get Radix Paeoniae Alba, crush it into coarse powder, add 50% ethanol to reflux and extract twice, the amount of alcohol added is 10, 10 times respectively, each time for 1.5 hours, reclaim ethanol under reduced pressure (pressure 0.05MPa, temperature 60 ℃), reduce Concentrate under pressure (pressure 0.08MPa, temperature 60°C) to form a thick paste (relative density at 60°C is 1.20-1.30), dry under reduced pressure (pressure 0.08Mpa, temperature 70°C) to obtain dry paste powder of the extract, pulverize, pass through 80 Mesh sieve, obtain Radix Paeoniae Alba extract fine powder;

[0056] 3. Take Acanthopanax, break it into thick pieces, add water to soak for 2 hours, decoct and extract ...

Embodiment 3

[0060] Gastrodia elata 6kg, Radix Paeoniae Alba 4kg, Acanthopanax 4kg, Suanzaoren 5kg.

[0061] Get above-mentioned crude drug, prepare by following method:

[0062] 1. Take Gastrodia elata, crush it into coarse powder, add 70% ethanol to reflux and extract twice, the amount of alcohol added is 10 and 10 times respectively, for 2 hours each time, recover ethanol under reduced pressure (pressure 0.05MPa, temperature 60°C), and depressurize Concentrate (pressure 0.08MPa, temperature 60°C) into a thick paste (relative density at 60°C is 1.20-1.25), dry under reduced pressure (pressure 0.08Mpa, temperature 70°C) to obtain a dry extract, crush it, and pass through an 80-mesh sieve , to obtain Gastrodia elata extract powder;

[0063] 2. Get Radix Paeoniae Alba, crush it into coarse powder, add 50% ethanol to reflux and extract twice, the amount of alcohol added is 10, 10 times respectively, each time for 1.5 hours, reclaim ethanol under reduced pressure (pressure 0.05MPa, temperatu...

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PUM

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Abstract

The invention discloses a preparation method of a traditional Chinese medicine composition with functions of treating insomnia, improving senile dementia, enhancing learning and memory abilities, resisting to depression and anxiety and soothing the nerves and benefitting intelligence.The traditional Chinese medicine composition comprises Rhizoma Gastrodiae, Radix Paeoniae Alba, Radix Acanthopanacis Senticosi and Semen Ziziphi Spinosae.The traditional Chinese medicine composition prepared with the method can be prepared into dosage forms acceptable clinically or pharmaceutically.Animal experiments show that the traditional Chinese medicine composition prepared with the method can improve the sleeping function and senile dementia and enhance learning and memory abilities, and has the anti-depression and anti-anxiety effects.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine composition preparations, and specifically relates to a preparation method of a traditional Chinese medicine composition for treating insomnia, improving senile dementia, improving learning and memory ability, antidepressant, anti-anxiety, and calming the mind. Background technique [0002] Traditional Chinese medicine believes that improper diet, impermanent daily life, emotional distress, excessive work and rest, and exogenous six evils (such as environmental pollution) can all cause the imbalance of qi, blood, yin and yang in the viscera, and eventually lead to poor sleep conditions. Therefore, for people with insufficient heart qi, hyperactivity of liver yang, and restless mind, the health care methods of calming liver yang, nourishing qi and calming the mind can fundamentally improve sleep. [0003] Senile dementia includes two pathological types of vascular disease and Alzheimer's...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61P25/20A61P25/28A61P25/24A61P39/06A61P25/22
CPCA61K36/8988A61K9/2059A61K36/254A61K36/65A61K36/71A61K36/725A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 王林元张建军
Owner 北京采瑞医药科技有限公司
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