The health-care medicinal wine of the present invention is special in that it comprises the following active ingredients: peony flower, peony bark, tea, hawthorn, ganoderma lucidum, astragalus, schisandra, ginseng, cinnamon, Morinda officinalis, rehmannia glutinosa, dogwood, Poria cocos, Yam, Alisma, licorice, liquor. The beneficial effects of the present invention are: it is a pure natural peony flower Chinese herbal medicine preparation, does not contain additives, has no toxic and side effects, is safe and reliable, can be used for a long time without damage, improves the immune function of the body, eliminates fatigue, strengthens the body, delays aging, and prolongs life. Fundamentally improve the physique, so as to achieve the elimination of diseases and the prevention of diseases without diseases. Moreover, the dosage is small, convenient to take, easy to absorb, quick to act, definite curative effect, wide range of medicinal use, and integrates treatment, prevention and health care, and is suitable for men, women, middle-aged and elderly people. Conforms to "three small", "three effects" and "five conveniences".