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Method for measuring dynamic contrast ratio and estimating transverse flow with OCT

A motion contrast and determination method technology, applied in the direction of diagnostic recording/measurement, application, diagnosis using tomography, etc., can solve the problem of poor accuracy of 3D visualization imaging

Active Publication Date: 2016-07-27
ZD MEDICAL HANGZHOU CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention provides a method for measuring dynamic contrast and estimating lateral flow by using OCT, a method for determining the vector of sample movement and a method for data collection, which solves the problem of poor accuracy of three-dimensional visual imaging of specific parts of the sample caused by sample movement. technical problem

Method used

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  • Method for measuring dynamic contrast ratio and estimating transverse flow with OCT
  • Method for measuring dynamic contrast ratio and estimating transverse flow with OCT
  • Method for measuring dynamic contrast ratio and estimating transverse flow with OCT

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Experimental program
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Embodiment 1

[0074] The method for determining the vector of fundus movement in one embodiment of the present invention comprises the following steps:

[0075] like Figure 1-01 As shown, the fundus image 100 at time T1 is obtained, the preset area of ​​the fundus image at time T1 is selected as the tracking image 110, and the image identification information for identification of the tracking image and the position of the tracking image at T1 are acquired;

[0076] like Figure 1-02As shown, the fundus image 200 at T2 is obtained, and the frame at the same position as the tracking image at T1 is found in the fundus image at T2 as the tracking frame 210;

[0077] Establish a plane Cartesian coordinate system with a point of the tracking frame as the origin, and use a point of the tracking frame 210 as the reference point to determine the maximum movable range of the reference point along the horizontal axis and the vertical axis, and the minimum movable range along the horizontal axis and ...

Embodiment 2

[0102] In the process of using optical coherence tomography to perform three-dimensional imaging, it is necessary to perform OCT scanning on the sample to collect data.

[0103] If the sample is moving, the optical coherence tomography galvanometer system for OCT scanning is not corrected before and after the sample movement, which will cause the lens of the optical coherence tomography galvanometer system for OCT scanning to change the scanning position of the sample. Therefore, for samples that may move, it is necessary to find the moving vector of the sample before scanning, and adjust the optical coherence tomography galvanometer system of OCT scanning accordingly, so that the lens of the optical coherence tomography galvanometer system of OCT scanning scans the same position of the sample. Scanning and collecting data is specifically implemented through the data collection method in Embodiment 2.

[0104] Implementation of the present invention provides a kind of data acq...

Embodiment 3

[0112] Embodiments of the present invention also provide a method for measuring dynamic contrast and estimating lateral flow using optical coherence tomography.

[0113]Method for measuring dynamic contrast and estimating lateral flow using optical coherence tomography, said method comprising the steps of,

[0114] The data collection method of Embodiment 2 is used for data collection, wherein the optical coherence tomography system is used to perform multiple B-scans on the sample to collect data, and in the multiple scans of the lateral region, each of the B-scans is included, Collecting data, the data at least includes phase information and intensity information;

[0115] Determination of phase change data, wherein the determination of the phase variance is based on the B-scan acquisition data, and the motion contrast of the sample depends on the phase variance.

[0116] Specifically, the determination of the phase change data includes the following steps: scanning the sam...

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Abstract

The invention discloses a method for measuring the dynamic contrast ratio and estimating transverse flow with OCT. A method for determining a sample movement vector includes the steps that a sample image at the time T1 is obtained, a preset area in the sample image is selected as a tracking image, and image identifying information and the position at the time T1 of the tracking image are obtained; a sample image at the time T2 is obtained, and the position the same as the position of the tracking image at the time T1 is found to serve as a tracking box; one point of the tracking box serves as a reference point, and the maximum movement ranges of the reference range along the transverse axis and the vertical axis are determined, and are divided into a plurality of movement positions; image identifying information of the tracking image at the time T1 when the reference point moves according to vectors and conducts transversal on movement positions and the association coefficients of the image identifying information of images in the tracking box when the reference point moves to all the movement positions are calculated, and the reference-point movement vector corresponding to the maximum value of the association coefficients is the vector of a sample at the time T2 relative to the time T1.

Description

technical field [0001] The invention relates to the technical field of optical imaging, in particular to a method for measuring dynamic contrast and estimating lateral flow by using OCT. Background technique [0002] Optical coherence tomography (OCT) is a non-invasive optical imaging technique. In recent years, in the field of medicine, especially in the field of ophthalmology, the optical coherence tomography system can perform three-dimensional visualization imaging of the faults of the test object (such as the retina of the fundus, the central retinal artery and vein, etc.), such as the fault of a specific part of the fundus. 3D visualization imaging. When performing three-dimensional visualization imaging of the tomography of a specific part of the fundus, it is first necessary to perform two-dimensional imaging of the fundus to determine the position of the fundus, find the specific part of the fundus through two-dimensional imaging of the fundus, and perform OCT scan...

Claims

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Application Information

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IPC IPC(8): A61B5/00
CPCA61B5/0066A61B5/0073
Inventor 唐磊
Owner ZD MEDICAL HANGZHOU CO LTD
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