A real-time controllable micro-droplet ejection device and method based on lithium niobate crystal

Abstract

The invention discloses a real-time controllable micro-droplet jetting device and method based on a lithium niobate crystal. The device comprises a laser device 1, a diaphragm 2, a circular adjustable attenuator 3, an optical reshaper 4, an equal-ratio optical splitter 5, a light intensity detector 6, a background light source 7, a lithium niobate chip 8, a transparent final motion chip horizontal movement platform 9, a focusing objective lens 10, a semi-transparent and semi-reflective mirror 11, a first-stage optical filter 12, a second-stage optical filter 13, a CCD camera 14 and a rigidity support 15. The real-time controllable micro-droplet jetting device is composed of a micro-droplet jetting optical path, a real-time observation optical path and a light intensity detection optical path, and the lithium niobate chip 8 and the transparent final motion chip horizontal movement platform 9 are core devices of the micro-droplet jetting device. Jetting of polarity droplets can be achieved through the simple device, and the jetting speed of the jetting device can be controlled. The technology can be used for mixing and separating of a trace of reagents and is of important significance in the fields such as biological and medical care, medicine diagnosis, food sanitation, environment monitoring and molecular biology.

Description

technical field [0001] The invention relates to a micro-droplet control technology, in particular to a real-time controllable micro-droplet ejection device and method based on lithium niobate crystals Background technique [0002] With the rapid development of microfluidic chips, more and more attention has been paid to the control technology of micro-droplets. Micro-droplet control technology is generally used in the analysis process of micro-sample in the fields of biology, chemistry, pharmacy, etc. It mainly involves the mixing and transportation of micro-quantity reagents. As one of the important components of micro-droplet manipulation technology, micro-droplet jetting technology has an important impact on the mixing and separation of trace reagents. development is of great importance. [0003] The ejection of micro-droplets refers to the process in which the micro-droplets to be ejected are locally driven by external forces to overcome the surface tension and rapidly...

AI Technical Summary

Problems solved by technology

At present, the existing micro-droplet ejection method has the disadvantages of complex core chip structure, high cost, strict requirements on the physical properties of the ejected droplets, and the inability to observe and control in real time.

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