Unlock instant, AI-driven research and patent intelligence for your innovation.

Auxiliary equipment and preparation method thereof

A technology of auxiliary equipment and drug-loading layer, applied in the field of medical devices, can solve problems such as infection, and achieve the effect of controlled release, low cost and effective release

Inactive Publication Date: 2016-09-28
MICROPORT SORIN CRM (SHANGHAI) CO LTD
View PDF3 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide an auxiliary device and its preparation method, aiming to solve the infection problem caused by CIED directly implanted into the human body in the prior art

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Auxiliary equipment and preparation method thereof
  • Auxiliary equipment and preparation method thereof
  • Auxiliary equipment and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] The auxiliary equipment in this example is suitable for patients with good physical fitness, quick recovery after infection, and general anti-infection needs. In order to reduce the risk of infection after implantation of cardiac implants, the following scheme is adopted:

[0069] Such as Figure 1-3 As shown, the embodiment of the present invention provides an auxiliary device, the auxiliary device includes an outer layer 1, a drug-loaded layer 2 and an inner layer 3, and the outer layer 1, the drug-loaded layer 2 and the inner layer 3 are all provided with a plurality of holes 5. The drug-loaded layer 2 is located between the inner layer 3 and the outer layer 1; the outer layer 1, the drug-loaded layer 2 and the inner layer 3 are made of biodegradable polymers, and the drug-loaded layer A drug is contained in the layer. The auxiliary device in this embodiment adopts a porous membrane structure, and the drug 4 is accommodated in the porous membrane structure, so that ...

Embodiment 2

[0094] The auxiliary equipment for the treatment of heart disease in this embodiment is suitable for patients who are sensitive to the flexibility of materials and intolerant to harder materials. Softer materials are selected as auxiliary equipment for heart implantation devices to have an anti-infection effect. Adopt the following scheme:

[0095] The structure of an auxiliary device for treating heart disease provided in this embodiment is basically the same as that in Embodiment 1, and only the differences will be described below. In the auxiliary device in this embodiment,

[0096] The thickness of the inner layer is preferably 0.02mm, and the percentage of the mass of the inner layer to the mass of the auxiliary equipment is preferably 15%;

[0097] The thickness of the drug-loaded layer is preferably 0.03mm, and the percentage of the total mass of the drug-loaded layer and the medicine contained therein in the mass of the auxiliary device is preferably 65%;

[0098] The...

Embodiment 3

[0111] The auxiliary equipment for the treatment of heart disease in this example is suitable for patients with good tolerance to chloramphenicol, and it has an anti-infection effect for the auxiliary equipment of the heart implanted device, and the following scheme is adopted:

[0112] The structure of an auxiliary device for treating heart disease provided in this embodiment is basically the same as that in Embodiment 1, and only the differences will be described below. In the auxiliary device in this embodiment,

[0113] The thickness of the inner layer is preferably 0.02mm, and the percentage of the mass of the inner layer to the mass of the auxiliary equipment is preferably 15%;

[0114] The thickness of the drug-loaded layer is preferably 0.04mm, and the percentage of the total mass of the drug-loaded layer and the medicine contained therein in the mass of the auxiliary device is preferably 70%;

[0115] The thickness of the outer layer is preferably 0.02 mm, and the mas...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
pore sizeaaaaaaaaaa
Login to View More

Abstract

The invention provides auxiliary equipment, which is used for wrapping a heart implanting device, and comprises a medicine carrying layer with holes, wherein the medicine carrying layer is made of biodegradable polymers; and medicine is accommodated in the medicine carrying layer. The auxiliary equipment provided by the invention has the advantages that a porous membrane structure is used, and medicine is accommodated in the porous membrane structure, so that the auxiliary equipment can release medicine in the CIED (Cardiovascular Implantable Electronic Device) implanting process; the occurrence of infection in the implanting process can be effectively prevented; the porous membrane structure with the holes is used, so that the heart implanting device can be in contact with body fluid through the holes, and the normal work is ensured; and meanwhile, the auxiliary equipment uses the multilayer structure, so that the medicine release can be effectively controlled.

Description

technical field [0001] The invention belongs to the field of medical devices, and relates to an auxiliary device and a preparation method thereof. Background technique [0002] Over the past few decades, the use of cardiac implanted devices (CIEDs), such as cardiac pacemakers (IPGs), cardioversion Defibrillator (ICD), Cardiac Resynchronization Defibrillator (CRT-D) patients have a clear growth trend, however, the implantation of CIED has brought complications while helping patients, and infection is the most common among them complication. [0003] Usually, there are many factors that lead to patient infection, such as factors related to medical devices, factors related to the perioperative period, factors related to the patient itself, factors related to the operator, and the environment of the operating room and many other factors. According to statistics, clinically, the probability of infection after CIED implantation is 1%-7%, and once infection occurs, the patient's ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/16A61L31/14A61M31/00
CPCA61L31/16A61L31/14A61L31/146A61L2300/402A61L2300/404A61M31/00
Inventor 周涓王励杨莹王亚茹邓瑜
Owner MICROPORT SORIN CRM (SHANGHAI) CO LTD