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Preparation method of externally-applied drug capable of improving microcirculation, dredging meridians and relieving collaterals, promoting blood circulation to remove blood stasis and treating rheumatism bone diseases

A technology for promoting blood circulation and removing blood stasis, rheumatic bone disease, applied to medical preparations containing active ingredients, bone diseases, medical formulas, etc., can solve problems such as gastric irritation, liver and kidney functions, and improve safety, Effect of improved extract quality and reduced energy consumption

Active Publication Date: 2016-10-12
TONGHUA SWAY PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In prior art, the medicine that treats waist, leg, shoulder, neck joint pain caused by rheumatic strain, hyperosteogeny etc. to cause microcirculation disorder is mostly oral preparations, taking too much not only has influence on liver and kidney function, but also on Stomach is also very irritating
External application of Chinese herbal medicines and appropriate application methods can also improve microcirculation.

Method used

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  • Preparation method of externally-applied drug capable of improving microcirculation, dredging meridians and relieving collaterals, promoting blood circulation to remove blood stasis and treating rheumatism bone diseases
  • Preparation method of externally-applied drug capable of improving microcirculation, dredging meridians and relieving collaterals, promoting blood circulation to remove blood stasis and treating rheumatism bone diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A medicine for external use capable of improving microcirculation, dredging meridians and collaterals, promoting blood circulation and removing blood stasis, and treating rheumatic bone disease, which is made into granules of the following raw materials in parts by weight: 10 parts of Passepartout, 8 parts of Fangfeng, and 8 parts of Atractylodes atractylodes , 8 parts of Angelica, 8 parts of Artemisia argyi, 8 parts of Duhuo, 8 parts of Spatholobus, 10 parts of Polygonum cuspidatum, 10 parts of Epimedium, 10 parts of Eucommia, 4 parts of Guizhi, 4 parts of Safflower, and 4 parts of Sappan.

[0031] Preparation method: Take 4 traditional Chinese medicinal materials of Fangfeng, Duhuo, Epimedium, and Sappan, and cut them into 10-15mm sections. Mix it with the above 4 traditional Chinese medicinal materials, put it in a heat reflux extraction tank, add 5 times the amount of water to soak for 1 hour, heat reflux for 5 hours, concentrate to a specific gravity of 1.15-1.20, d...

Embodiment 2

[0033] A medicine for external use capable of improving microcirculation, dredging meridians and collaterals, promoting blood circulation and removing blood stasis, and treating rheumatic bone disease, which is made into granules of the following raw materials in parts by weight: 7 parts of Passepartout, 9 parts of Fangfeng, and 9 parts of Atractylodes , 9 parts of Angelica, 9 parts of Artemisia argyi, 9 parts of Duhuo, 9 parts of Caulis Spatholobus, 8 parts of Polygonum cuspidatum, 8 parts of Epimedium, 8 parts of Eucommia, 5 parts of Guizhi, 5 parts of Safflower, and 5 parts of Sappan.

[0034] Preparation method: Take 4 traditional Chinese medicinal materials of Fangfeng, Duhuo, Epimedium, and Sappan, and cut them into 10-15mm sections. Mix it with the above 4 traditional Chinese medicinal materials, put it in a heat reflux extraction tank, add 5 times the amount of water to soak for 1 hour, heat reflux for 5 hours, concentrate to a specific gravity of 1.15-1.20, dry at 80 °...

experiment example 1

[0036] Process selection orthogonal experiment results are:

[0037] factor level table

[0038]

[0039] Orthogonal experiment design table and results

[0040]

[0041] The optimal experimental conditions selected from the above test results are: the extraction time of the medicinal materials is 5 hours, and the amount of the solvent is 5 times that of the medicinal materials.

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PUM

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Abstract

The invention relates to an externally-applied drug or healthcare product, in particular to a preparation method of an externally-applied drug capable of improving microcirculation, dredging the meridians and relieving the collaterals, promoting blood circulation to remove blood stasis and treating rheumatism bone diseases. The preparation method comprises the steps that four traditional Chinese medicinal materials including radix saposhnikoviae, radix angelicae pubescentis, herba epimedii and sappan wood are cut into segments with the size of 10 mm to 15 mm, beautiful sweetgum fruits, rhizoma atractylodis, radix angelica sinensis, folium artemisiae argyi, caulis spatholobi, rhizoma polygoni cuspidate, cortex eucommiae, cassia twigs and safflower are mixed with the four traditional Chinese medicinal materials, the mixture is placed in a heat reflux extraction tank, soaked for 1 hour by adding water and subjected to heating reflux extraction for 5 hours, an extracting solution is concentrated until the specific gravity is 1.15 to 1.20, dried at 80 DEG C and then crushed into fine powder, and the fine powder is put into a granulating machine to be granulated; wet particles are dried for 2 minutes to 3 minutes by controlling the temperature to be 45 DEG C+ / -5 DEG C, the dried particles are placed in an oscillating granulator to be subjected to size stabilization with a 16-mesh sieve, packaging is conducted, and then the externally-applied drug is obtained. The externally-applied drug has the healthcare function of improving microcirculation and is suitable for being used by people suffering from microcirculation disturbance caused by waist, leg, shoulder and neck joint pain, osteoproliferation and the like which are caused by rheumatism strain.

Description

[0001] The application of the present invention is for the branch titled "a drug for external use capable of improving microcirculation, dredging meridians and collaterals, promoting blood circulation and removing blood stasis, and treating rheumatism and bone disease" and its preparation method, patent application number: 201410313520.8, application date: 2014.7.3 case application. technical field [0002] The invention relates to a medicine for external use, a health care product and a preparation method, in particular to a preparation method of a medicine for external use that can improve microcirculation, dredge meridians and collaterals, activate blood circulation and remove blood stasis, and treat rheumatism and bone disease (commercial name: Sway Brand Huoluo Soak leg particles). Background technique [0003] In prior art, the medicine that treats waist, leg, shoulder, neck joint pain caused by rheumatic strain, hyperosteogeny etc. to cause microcirculation disorder i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/704A61K9/16A61P29/00A61P19/08A61P19/02
CPCA61K9/0014A61K9/1617A61K36/185A61K36/232A61K36/238A61K36/282A61K36/284A61K36/286A61K36/296A61K36/46A61K36/48A61K36/486A61K36/54A61K36/704A61K2236/331A61K2236/51A61K2300/00
Inventor 杜明珠
Owner TONGHUA SWAY PHARM CO LTD
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