Organic matter detection device and detection method of bipolar proton transfer reaction mass spectrometer

Abstract

The device comprises an organic matter detection device and an organic matter detection method of a bipolar proton transfer reaction mass spectrometer. The organic matter detection device mainly comprises a common discharge ion source, two sets of positive and negative reaction tubes, positive and negative transition chambers and positive and negative mass spectrometers, and a set of common vacuum pump group. The organic matter detection method comprises the steps of: achieving the extraction of positive and negative reaction ions of H3O<+> and OH<-> by means of the discharge ion source, and realizing double efficient ionization of a matter to be detected; and accurately judging molecular weight of the matter to be detected according to a difference value (2) of charge-to-mass ratios of product ions ([MH]<+>, [M H] <->), and realizing accurate recognition and online highly-sensitive detection of the matter to be detected. Compared with a proton transfer reaction mass spectrometer and a proton counter-transfer reaction mass spectrometer, the set of the organic matter detection device is formed by the common discharge iron source, the vacuum pump group and the like, the comparability of obtained results is higher, and the cost is lower. The organic matter detection device and the organic matter detection method can realize the positive and negative ion cooperative recognition and highly-sensitive online detection of the organic matter of the bipolar proton transfer reaction mass spectrometer.

Description

technical field [0001] The invention belongs to the field of analysis and detection, and in particular relates to a bipolar proton transfer reaction mass spectrometry organic detection device and detection method. Background technique [0002] The most commonly used reagent ion in proton transfer reaction mass spectrometry is H 3 o + , through the proton transfer reaction (H 3 o + +M—>MH + +H 2 O), the analyte can be ionized, and finally can be detected by mass spectrometry to obtain molecular weight information and concentration information. Due to the advantages of high sensitivity, fast response, soft ionization, and no need for calibration, this technology has attracted more and more attention in the field of organic matter analysis and detection in recent years. However, due to the different characteristics of the analytes, the required reaction conditions are also different, which leads to the fact that under certain reaction conditions, some analytes sometime...

AI Technical Summary

Problems solved by technology

However, like proton transfer reaction mass spectrometry, there are also potential interferences from a small number of fragment ions

This deficiency has a certain impact on the qualitative analysis capabilities of proton transfer reaction mass spectrometry and proton reverse transfer reaction mass spectrometry, which limits its application in the detection field to a certain extent.

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