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Selectively delivering particles into the distal portion of the left gastric artery

A technology for particulate matter and arteries, applied in the fields of filters in blood vessels, medical science, balloon catheters, etc., can solve problems such as adverse side effects of bariatric surgery complications

Active Publication Date: 2016-10-12
ENDOBAR SOLUTIONS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

But bariatric surgery is traumatic and can be accompanied by significant surgical complications and / or adverse side effects

Method used

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  • Selectively delivering particles into the distal portion of the left gastric artery
  • Selectively delivering particles into the distal portion of the left gastric artery
  • Selectively delivering particles into the distal portion of the left gastric artery

Examples

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example 1

[0038] A study in five obese subjects has been conducted to determine the feasibility, safety and efficacy of embolization of the distal portion of the left gastric artery to reduce plasma ghrelin levels and body weight.

[0039] All subjects underwent gastroscopy prior to embolization to assess for the presence of peptic ulcer or gastritis. Gastritis was found in two subjects who subsequently underwent medical treatment. Embolization was performed only after subsequent gastroscopy showed marked improvement in mucosal irritation.

[0040] Body weight is measured and routine blood samples are obtained prior to embolization, including complete blood count, electrolytes, and creatinine.

[0041] During the course of treatment, the 6-Fr strand approach was obtained. More specifically, a 6-Fr Heartrail II JR-4.0 guiding catheter (Terumo Europe N.V., Leuven, Belgium) was used to engage the celiac ostium and angiography was performed in different projections to identify the origin ...

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PUM

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Abstract

Embolization particles can be safely delivered to the left gastric artery of a patient by introducing the distal end of a catheter in the patient's left gastric artery, inflating a balloon located near the distal end of the catheter so that the balloon prevents blood from flowing through the left gastric artery, and injecting a mixture of particles and contrast agent into the proximal end of the catheter so that they flow through the catheter. In addition, a path is provided for blood to flow into the catheter through an opening in the sidewall of the catheter at a position that is proximal to the balloon, and out through the distal end of the catheter. This blood flow helps to carry the particles along to their destination in the distal portion of the left gastric artery. The particles are also prevented from flowing into portions of the patient's artery system that are proximal of the balloon.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of US Provisional Application No. 61 / 928,550, filed January 17, 2014, which is hereby incorporated by reference in its entirety. Background technique [0003] Obesity is recognized as a major public health problem leading to reduced quality of life and chronic diseases such as metabolic syndrome, diabetes, hypertension, congestive heart failure, atherosclerosis, sleep apnea, and others. Lifestyle changes can be used to treat obesity, but lifestyle changes are not always possible, especially in the long-term. Drug therapy is a conventional treatment for obesity, but is often accompanied by various complications and undesirable side effects. [0004] Bariatric surgery is another conventional treatment used for obesity. One of the recognized benefits of bariatric surgery is the reduction of ghrelin production. Ghrelin (a neuropeptide produced primarily in the fundus of the stomach) is ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B17/12A61F2/01
CPCA61B17/12036A61B17/1204A61B17/12109A61B17/12136A61B17/12186A61B2017/00818A61B2017/1205A61B2017/22067A61M2025/1095A61F2/958A61B2090/3966
Inventor N·基普希德R·J·索拉尔
Owner ENDOBAR SOLUTIONS