Application of arsenic trioxide in preparation of psoriasis therapeutics

A technology for arsenic trioxide and psoriasis, which is used in drug combinations, skin diseases, pharmaceutical formulations, etc., to achieve the effects of unique formulations, definite curative effects, and symptom improvement.

Inactive Publication Date: 2016-10-26
张春
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is still a lack of very satisfactory treatment methods for the treatment of psoriasis in the world. Therefore, it is an important topic in the field of dermatology to find a good, safe and reliable treatment method.

Method used

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  • Application of arsenic trioxide in preparation of psoriasis therapeutics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1: Preparation of capsules

[0026] Arsenic trioxide 5 grams Starch 995 grams, first dry the starch, pass through a 120-mesh sieve, then mix with arsenic trioxide, pass through a 120-mesh sieve twice, mix well, and make a total of 1000 capsules, each containing 5 mg of arsenic trioxide.

Embodiment 2

[0027] Example 2: Preparation of Tablets

[0028] Add 50 grams of arsenic trioxide, add 9950 grams of starch, mix thoroughly, wet with ethanol, make soft material after mixing, make granules, dry, add appropriate amount of lubricant, and press into 10,000 tablets, each containing 5 mg of arsenic trioxide. Regular coat, finish.

Embodiment 3

[0029] Example 3: Preparation of injection

[0030] 10 grams of arsenic trioxide, 10 ml of methanol, and 100 ml of propylene glycol are fully dissolved, add water for injection to 4000 ml, filter, encapsulate, sterilize, and divide into 5mg / 2ml injection into medicine bottles. Contains 2.5 mg of arsenic trioxide per ml.

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PUM

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Abstract

The invention relates to application of arsenic trioxide in the preparation of psoriasis therapeutics. The invention is characterized in that the application refers to the use of arsenic trioxide as a main effective ingredient in the preparation of psoriasis therapeutics, including arsenic trioxide 0.01-2% by weight. The invention has the advantages that the composition is unique, the therapeutic effect is clear, good economy and safety are achieved, no significant toxic and side effect occurs, and the composition has the effects of activating blood to dredge collaterals, removing wind and evil, harmonizing ying and wei, and balancing yin and yang and is suitable for psoriasis patients to administer; clinical researches show that it is possible to significantly improve symptoms of the psoriasis patients, with 85.71% of total effective rate.

Description

1. Technical field [0001] The present invention relates to the application of arsenic trioxide in preparing medicine for treating psoriasis (psoriasis) 2. Technical background [0002] Psoriasis, commonly known as psoriasis, is a common skin disease characterized by excessive keratinocyte proliferation and chronic inflammatory response in the dermis. %, the prevalence in the natural population is 0.1%-3%, and the annual incidence is about 0.6‰. Its etiology and pathogenesis are not yet fully understood. It is more clear that the combination of genetic regulation and environmental factors causes epidermal hyperproliferation, parakeratosis, telangiectasia and hyperplasia in the dermis, and clinical manifestations are erythema and superficial hyperplasia. Lots of silvery white scales. Chinese medicine believes that the lack of nourishment and blood in the body, the internal heat of blood, the elimination of dryness and the generation of wind, and the lack of nourishment of th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/36A61P17/06
CPCA61K33/36
Inventor 张春
Owner 张春
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