Composition with anti-inflammatory function and preparation method and application thereof
The technology of an anti-inflammatory effect and a composition is applied in the field of a composition with an anti-inflammatory effect and the preparation thereof, which can solve the problems of organ function concealment, poor wound healing, and scratching organ performance, etc., achieve a good anti-inflammatory effect, protect the heart and lungs, etc. The effect of organization and high safety
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Embodiment 1
[0031] A composition with anti-inflammatory effect, prepared by the following method:
[0032] 1. Prepare raw materials.
[0033] Put the whole cherry fruit into an oven at 60°C, bake for 24-48 hours, take it out, and cool to room temperature. Take the dried cherries and put them into a pulverizer to pulverize them into fine grains to obtain the dried cherries.
[0034] Put Cordyceps militaris in an oven at 60°C, bake for 24-48 hours, take it out, and cool to room temperature. Take the dried Cordyceps militaris and put them into a pulverizer to pulverize into fine grains to obtain the dried Cordyceps militaris.
[0035] Two, extraction.
[0036] Take 100g dried cherry and 100g dried Cordyceps militaris respectively, place them in a 2000ml round bottom flask, add 8ml ethanol aqueous solution according to the amount of each gram of raw material (that is, the ratio of material to liquid is 1:8), and the volume percentage is 95% % ethanol aqueous solution 1600ml, reflux extrac...
experiment example
[0046] The extract prepared by above-mentioned embodiment and comparative example is carried out anti-inflammatory experiment, and specific method is as follows:
[0047] 1. Method.
[0048] 1. Administration.
[0049]Mice with a body weight of 18-22g were randomly divided into positive group (administered with dexamethasone), negative group (administered with saline), water layer extract group, ethyl acetate layer extract group A, petroleum ether layer Extract group, ethyl acetate layer extract group B, ethyl acetate layer extract group C, ethyl acetate layer extract group D, 10 mice in each group.
[0050] They were administered by subcutaneous injection at a dose of 10mg / 20g for 5 days.
[0051] 2. Anti-inflammatory test.
[0052] (1), prepare croton oil.
[0053] Croton oil prescription: 2% croton oil, 20% absolute ethanol, 78% ether (volume ratio) preparation.
[0054] (2), method.
[0055] On the 5th day after the administration of the mice, 1 hour after the admini...
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