A kind of aloe antibacterial gel and preparation method thereof

A technology of gel and aloe vera, which is applied in the direction of antifungal agents, antibacterial drugs, capsule delivery, etc., can solve the problems of decreased reproductive local immunity, destruction of mucosal secretion function, inconvenient use of dosage forms, etc., to achieve the promotion of adrenal cortex hormone Synthetic, good comprehensive effect, reduce vaginal bleeding effect

Active Publication Date: 2018-07-17
汪红梅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the above-mentioned medicines for gynecological inflammations have the following problems: 1. Almost all medicines for gynecological inflammations on the market will destroy the reproductive tract environment and the self-secretion function of the mucous membrane, resulting in the destruction of reproductive local immunity. 2. The compatibility of the prescription is unreasonable, the dosage form is inconvenient to use, the function is limited, and the comprehensive curative effect is not obvious; 3. It is an after-event drug and cannot be used as a preventive and therapeutic agent. Long-term use of health drugs

Method used

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  • A kind of aloe antibacterial gel and preparation method thereof
  • A kind of aloe antibacterial gel and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0029] An aloe antibacterial gel, which consists of the following components in parts by weight: 0.2% hypromellose, 1% propylene glycol, 0.1% chlorhexidine acetate, 0.01% hyaluronic acid, 1% aloe extract, 1% snow lotus extract Comfrey extract 0.5%, comfrey extract 0.5%, and the rest is water; among them, hyaluronic acid, snow lotus extract and comfrey extract are all liposome-embedded or nano-microcapsule-encapsulated separately before mixing. The pH of the above-mentioned aloe antibacterial gel is 4.5, and the pH regulator is sodium dihydrogen phosphate. The pH is close to the pH of the vaginal environment of the human body, will not destroy the flora that maintains the normal pH of the vagina, will not destroy the internal balance of the human body, has little side effects, and can be used for a long time.

[0030] The aloe extract is prepared by the following method: wash, peel and sterilize the fresh leaves of aloe, put them into a cell crusher for beating, add 1% pectinas...

Embodiment 2

[0044] An aloe antibacterial gel, which consists of the following components in parts by weight: 10% hypromellose, 10% propylene glycol, 3% chlorhexidine acetate, 1% hyaluronic acid, 10% aloe extract, and snow lotus extract Comfrey extract 5%, comfrey extract 5%, and the rest is water; among them, hyaluronic acid, snow lotus extract and comfrey extract are all liposome-embedded or nano-microcapsule-wrapped separately before mixing. The pH of the above-mentioned aloe antibacterial gel is 4.6, and the pH regulator is sodium dihydrogen phosphate. The pH is close to the pH of the vaginal environment of the human body, will not destroy the flora that maintains the normal pH of the vagina, will not destroy the internal balance of the human body, has little side effects, and can be used for a long time.

[0045] The aloe extract is prepared by the following method: wash, peel and sterilize the fresh leaves of aloe, put them into a cell breaker for beating, add 5% pectinase and 0.5% v...

Embodiment 3

[0059] An aloe antibacterial gel, which consists of the following components in parts by weight: hypromellose 8%, propylene glycol 8%, chlorhexidine acetate 1%, hyaluronic acid 0.5%, aloe extract 8%, snow lotus extract Comfrey extract 2%, comfrey extract 2%, and the rest is water; among them, hyaluronic acid, snow lotus extract and comfrey extract are all liposome-embedded or nano-microcapsule-wrapped separately before mixing. The pH of the above-mentioned aloe antibacterial gel is 4.4, and the pH regulator is sodium dihydrogen phosphate. The pH is close to the pH of the vaginal environment of the human body, will not destroy the flora that maintains the normal pH of the vagina, will not destroy the internal balance of the human body, has little side effects, and can be used for a long time.

[0060] The aloe extract is prepared by the following method: wash, peel and sterilize the fresh leaves of aloe, put them into a cell crusher for beating, add 3% pectinase and 0.4% vitami...

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Abstract

The invention provides an aloe anti-bacterial gel. The aloe anti-bacterial gel is prepared from the following components in percentage by weight: 0.2-10 % of hydroxypropyl methylcellulose, 1-10 % of propylene glycol, 0.1-3 % of chlorhexidine acetate, 0.01-1% of hyaluronic acid, 1-10 % of aloe extracting solution, 0.5-5 % of lanatechead saussurea herb extract, 0.5-5 % of radix arnebiae seu lithospermi extract, and the balance of water, wherein before mixing, the hyaluronic acid, the lanatechead saussurea herb extract and the radix arnebiae seu lithospermi extract are independently coated by adopting lipidosome or nanometer microcapsules. The invention further provides a preparation method of the gel. The aloe anti-bacterial gel can diminish inflammation and resist bacteria, and regulate the functions of the female reproductive system, the efficacies of the most effective ingredients of the medicinal materials can be exerted, and the aloe anti-bacterial gel is suitable for being safely used for a long term.

Description

【Technical field】 [0001] The invention relates to a compound Chinese herbal medicine gynecological gel, in particular to an aloe antibacterial gel and a preparation method thereof. 【Background technique】 [0002] Reproductive tract infection is an important factor that endangers women's health, and the root cause of reproductive tract infection is various opportunistic pathogenic bacteria that are prone to lurk in the internal and external genitals, such as staphylococcus, streptococcus, Escherichia coli, anaerobic bacteria, sexually transmitted pathogens , Candida albicans and Mycoplasma, Chlamydia, etc. When the internal and external environment of the human body changes and loses balance, pathogens will take advantage of the situation and endanger the health of the body. [0003] my country's external gynecological medicines include Chinese patent medicines, antibiotics, chemical disinfectants and Chinese and Western medicine mixtures, among which chemical disinfectants ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/06A61K9/127A61K9/51A61K36/896A61K36/886A61K47/38A61P31/04A61P31/22A61P31/10A61P33/02A61P31/18A61P5/30A61P15/00A61K31/155A61K31/728
CPCA61K9/0034A61K9/06A61K9/127A61K9/51A61K31/155A61K31/728A61K36/285A61K36/30A61K36/886A61K36/896A61K47/38A61K2236/37A61K2300/00
Inventor 尹志明刘动勤
Owner 汪红梅
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