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Rare ginsenoside composition containing rare ginsenoside Rh4

A kind of technology of ginsenoside and composition, applied in the field of biomedicine

Inactive Publication Date: 2017-02-22
SHAANXI GIANT BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, there is no report on how to combine ginsenosides on the basis of single components to enhance their antitumor effects and prepare highly efficient and low-toxic antitumor drugs.

Method used

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  • Rare ginsenoside composition containing rare ginsenoside Rh4
  • Rare ginsenoside composition containing rare ginsenoside Rh4
  • Rare ginsenoside composition containing rare ginsenoside Rh4

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Example 1 Preparation of Ginsenoside Gum Rh4 Capsules

[0047]Weigh 10kg of ginsenoside Rh4, 0.2kg of citric acid, add 68.5kg of starch, mix well, sieve, use ethanol aqueous solution as binder to make a suitable soft material, granulate with 18 mesh sieve, and dry in an oven at 60°C for 5 hours. Sieve with a 16-mesh sieve, add 500g of magnesium stearate, and mix well to obtain capsules.

Embodiment 2

[0048] Embodiment 2 Ginsenoside gum Rh4 tablet preparation

[0049] Take ginsenoside Rh4 50kg, citric acid 1kg, pulverize into fine powder, add microcrystalline cellulose 10kg, sodium carboxymethyl starch 2kg, mix well, wet granulate, dry, add talcum powder 2kg, magnesium stearate 0.3kg, Tablets were made by conventional tablet preparation process.

Embodiment 3

[0050] Example 3 Preparation of Ginsenoside Gum Rh4 Powder

[0051] Take 40kg of ginsenoside Rh4 and 0.8kg of citric acid, pulverize into fine powder, add 0.3kg of magnesium stearate, mix evenly, and pack into powders.

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Abstract

The present invention provides a rare ginsenoside composition containing rare ginsenoside Rh4. The rare ginsenoside composition comprises 100 parts by weight of ginsenoside Rh4 and 0.05-5 parts by weight of an edible C2-C6 organic dicarboxylic acid or tricarboxylic acid. According to the present invention, the rare ginsenoside composition has advantages of significant antitumor activity, high efficiency, and low toxicity.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to a rare ginsenoside composition containing rare ginsenoside Rh4, which has anti-tumor activity, high efficiency and low toxicity. Background technique [0002] Cancer is the second most threatening human disease after cerebrovascular disease. The incidence of cancer in my country exceeds 3 million people every year, and the incidence of lung cancer, breast cancer, and esophageal cancer increases year by year, among which the annual growth rate of lung cancer incidence is 26.8%, and the annual growth rate of breast cancer incidence is 6.8%. Over the past 30 years, the mortality rate of breast cancer has increased by 96%, and the mortality rate of lung cancer has soared by 465%. my country's cancer prevention and control work is urgent and the situation is grim. [0003] However, there has not been any report on how to combine ginsenosides on the basis of single components to enhance the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/704A61P35/00A61K31/19A61K31/194
CPCA61K31/704A61K31/19A61K31/194A61K2300/00
Inventor 段志广范代娣马晓轩黄蓉范翠英张婧婧严建亚
Owner SHAANXI GIANT BIOTECHNOLOGY CO LTD
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