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Autogenous cartilage material for nose plastic filling and preparation method of such material

An autologous and cartilage technology, which is applied to the material and preparation field of autologous cartilage for rhinoplasty, can solve the problems of easy displacement and wear, complicated production process, etc., and achieve the effects of preventing pain and preventing movement.

Pending Publication Date: 2017-03-08
大连裕辰科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention provides a material for filling autologous cartilage in rhinoplasty and a preparation method thereof, so as to solve the problems in the prior art that the production process is relatively complicated and prone to displacement and wear.

Method used

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  • Autogenous cartilage material for nose plastic filling and preparation method of such material
  • Autogenous cartilage material for nose plastic filling and preparation method of such material
  • Autogenous cartilage material for nose plastic filling and preparation method of such material

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preparation example Construction

[0042] refer to image 3 As shown, the present invention also proposes a preparation method for filling autologous cartilage materials for rhinoplasty, comprising the following steps:

[0043] A) Taking bone, obtaining autologous cartilage in a sterile environment, wherein the autologous cartilage is autologous rib and autologous ear cartilage.

[0044] B) treatment, the obtained autologous cartilage is degreased, decalcified, deproteinized and sterilized sequentially;

[0045] C) Sculpting, sculpting the autologous cartilage after the above treatment into the desired shape.

[0046] Concrete process in the step B of the present invention comprises:

[0047] (1) immersing the autologous cartilage in a mixed liquid of chloroform and methanol for 6-24 hours; wherein: the volume ratio of chloroform and methanol in the mixed liquid of chloroform and methanol is 1:1;

[0048] (2) adding the autologous cartilage treated in the above step (1) into the hydrochloric acid solution, a...

Embodiment 1

[0053] 1. Obtain autologous rib cartilage in a sterile environment; preferably take the eleventh or twelfth rib, clean it with distilled water and soak it;

[0054] 2. Immerse the autologous cartilage in a mixed liquid of chloroform and methanol for 24 hours to degrease; wherein: the volume ratio of chloroform and methanol in the mixed liquid of chloroform and methanol is 1:1, and wash it with distilled water after taking it out;

[0055] 3. Immerse the degreased autologous cartilage in a hydrochloric acid solution with a concentration of 0.5mol / L, and keep stirring for 12 hours for decalcification, and wash it with distilled water after taking it out;

[0056] 4. Immerse the decalcified autologous cartilage in a mixed solution of TritonX-100 and ammonia water for 72 hours to deproteinize; wherein, the volume percentage of TritonX-100 in the mixed solution of TritonX-100 and ammonia water is 1.5%, The mass percentage of ammonia is 0.3%, and after taking it out, it is cleaned w...

Embodiment 2

[0060] 1. Obtain autologous ear cartilage in a sterile environment; wash and soak in distilled water;

[0061] 2. Immerse the autologous cartilage in a mixed liquid of chloroform and methanol for 24 hours to degrease; wherein: the volume ratio of chloroform and methanol in the mixed liquid of chloroform and methanol is 1:1, and wash it with distilled water after taking it out;

[0062] 3. Immerse the degreased autologous cartilage in a hydrochloric acid solution with a concentration of 0.6mol / L, and keep stirring for 12 hours for decalcification, and wash it with distilled water after taking it out;

[0063] 4. Immerse the decalcified autologous cartilage in a mixed solution of TritonX-100 and ammonia water for 72 hours to deproteinize; wherein, the volume percentage of TritonX-100 in the mixed solution of TritonX-100 and ammonia water is 1%, The mass percentage of ammonia is 0.3%, and after taking it out, it is cleaned with distilled water;

[0064] 5. Place the deproteinize...

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Abstract

The invention relates to an autogenous cartilage material for nose plastic filling and a preparation method of such material. The autogenous cartilage material structurally comprises a nasal bone matrix prepared from autogenous cartilage, and the nasal bone matrix comprises a nasal tip, a nasal columella and a nose bridge, wherein the nose bridge is connected with the nasal columella through the nose tip, and the lower portion of the nose bridge is composed of two intersectional V-shaped nose bridge segments. A nose bone of a human body is positioned between the two nose bridge segments, and the nose bridge is thinned gradually from the middle to two sides. The autogenous cartilage material has the advantages that through the design of the nose bridge segments, a prosthesis can be in close contact with the nose bone, and displacement or wear is avoided; body fluid can flow into pores in the nose bridge to promote growth of human tissues, a nose can be connected with the nose prosthesis integrally, and accordingly the nose prosthesis can be protected from moving, shedding and ulcerating, and postoperative pain of a patient is prevented. The preparation method is applicable to treatment of autogenous cartilages and alloplastic bones.

Description

technical field [0001] The invention relates to the technical field of plastic surgery, in particular to a material for filling autologous cartilage in nasal plastic surgery and a preparation method thereof. Background technique [0002] Rhinoplasty (facelift) surgery is to change the height and shape of the nose by implanting appropriate materials so that it is in harmony with other parts of the face. It is the most common surgery in the field of plastic surgery. [0003] In medicine, there are many kinds of rhinoplasty materials, such as medical silicone rubber, autologous cartilage, animal tendon or ligament, expanded body (polytetrafluoroethylene), hyaluronic acid, etc. There are also many preparation methods for nasal bridge prosthesis. Among them, autologous cartilage is self-sourced, so there will be no rejection and no allergies, but it is difficult to shape during the production process. Animal tendons and ligaments are used as raw materials, because their composit...

Claims

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Application Information

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IPC IPC(8): A61L27/56A61L27/36A61F2/18
CPCA61L27/3612A61L27/3683A61L27/56A61F2/186A61F2210/00A61L2430/40
Inventor 于浩
Owner 大连裕辰科技发展有限公司
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