Brain nuclear magnetic resonance image-based multi-dimensional feature classification algorithm

A nuclear magnetic resonance image, multi-dimensional feature technology, applied in the field of image processing, can solve the problem of inability to analyze the functional connection of specific parts, and achieve the effect of high accuracy and strong applicability

Active Publication Date: 2017-03-08
SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
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Problems solved by technology

The existing features based on brain magnetic resonance images are mainly based on voxel-based morphological features. The classification algorithm established by using this feature can only find out the structural changes of specific parts, but cannot analyze the changes of functional connections of specific parts. At present, there is no good classification algorithm for clinical use that can simultaneously analyze the changes in human body structure and the structure-functional connection on the basis of brain MRI images, which requires extracting higher-dimensional information from brain MRI images. feature and establish a classifier to realize the classification algorithm of related diseases

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  • Brain nuclear magnetic resonance image-based multi-dimensional feature classification algorithm
  • Brain nuclear magnetic resonance image-based multi-dimensional feature classification algorithm
  • Brain nuclear magnetic resonance image-based multi-dimensional feature classification algorithm

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Embodiment 1

[0067] On the basis of the multidimensional feature classification algorithm for brain MRI images provided in the above embodiments, this embodiment provides an example of a multidimensional feature classification algorithm based on brain MR images.

[0068] First, a brain MR image is divided into regions to extract several ROI features. A ROI feature includes several types of labeling features for marking a brain MR image, such as gray matter volume, white matter volume, cerebrospinal fluid volume, cerebral cortex thickness, and brain volume. Marker features of classes such as cortical surface area. In order to eliminate individual differences, the above-mentioned types of marker features were normalized. Correspondingly, the normalization of gray matter volume, white matter volume, and cerebrospinal fluid volume was performed by dividing the volume of each ROI by the total intracranial volume to make individual differences Minimized; cortical thickness was normalized by divi...

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Abstract

The invention discloses a brain MR image-based multi-dimensional feature classification algorithm. The algorithm comprises the steps of performing regional division on brain MR images and extracting a plurality of ROI characteristics; selecting a mark characteristic, establishing a correlation among the ROI characteristics about the mark characteristic, and forming related characteristics; extracting the ROI characteristics and the related characteristics from the brain MR images to form an ROI characteristic set and a related characteristic set; selecting an optimal ROI characteristic subset and an optimal related characteristic subset from the ROI characteristic set and the related characteristic set through a mixed characteristic algorithm; and setting a weight factor of a function proportion of the ROI characteristics in a classifier, and integrating the optimal ROI characteristic subset and the optimal related characteristic subset through the weight factor and a multi-kernel SVM model to form a multi-kernel classifier. According to the algorithm, high-dimensional characteristics are obtained; local change and function connection change caused by related diseases can be analyzed at the same time; the classification accuracy is high; and the algorithm can assist in diagnosis of different diseases.

Description

technical field [0001] The present invention relates to the technical field of image processing, and more specifically, the present invention relates to a multidimensional feature classification algorithm based on brain magnetic resonance images. Background technique [0002] Medical imaging refers to the technology and processing process of obtaining internal tissue images of the human body or a certain part of the human body in a non-invasive manner for medical treatment or medical research. It includes the following two relatively independent research directions: medical imaging system and medical image processing. The former refers to the process of image formation, including the research on imaging mechanism, imaging equipment, imaging system analysis and other issues; the latter refers to the further processing of the obtained image, the purpose of which is to make the original image that is not clear enough Restoration, or to highlight certain feature information in ...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T7/00G06K9/32G06K9/46G06K9/62
CPCG06T7/0012G06T2207/30016G06T2207/10088G06T2207/20081G06V10/25G06V10/44G06F18/2411
Inventor 彭博戴亚康史文博周志勇佟宝同
Owner SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
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