Extraction method and application of total phenolic acid extract of broussonetia papyrifera leaves

Abstract

The invention belongs to the field of traditional Chinese medicine, and particularly relates to an extraction method and application of a total phenolic acid extract of broussonetia papyrifera leaves. The extraction method specifically comprises the following steps: acquiring an appropriate amount of naturally dried broussonetia papyrifera leaves, and crushing the leaves into powder; adding the broussonetia papyrifera leaf powder into a supercritical CO2 extraction kettle, extracting the leaf powder for 1.5 h by using 85 percent ethanol as an entrainer under conditions that the extraction pressure is 50.0 MPa, the extraction temperature is 50 DEG C, the flow rate of CO2 is 10 kg h<-1>, the separation pressure is 5.8 MPa, and the separation temperature is 40 DEG C; and carrying out decompression concentration and decompression drying on an ethanol solution obtained after the extraction, thus obtaining the total phenolic acid extract of the broussonetia papyrifera leaves. The total phenolic acid extract of the broussonetia papyrifera leaves obtained by the extraction method provided by the invention is simple in method, low in cost and high in purity and lays a foundation of being developed into a drug resisting Parkinson disease.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a new extraction method and application of total phenolic acids in leaves of Structur alba. Background technique [0002] mulberry tree ( Broussonetia papyrifera ) is a plant of the genus Moraceae, which is distributed in the Yellow River, Yangtze River, and Pearl River basins in my country. It is also distributed in Japan, Vietnam, India and other countries, and its resources are very rich. The ripe fruit of the mulberry tree is called "Chushizi", which is recorded in the "Chinese Pharmacopoeia" in previous editions. It is a common Chinese medicine, which has the effects of nourishing the kidney, clearing the liver, improving eyesight and diuresis. The leaves of the mulberry tree are also known as mulberry leaves, which are cool in nature, sweet in taste, non-toxic, can clear away heat and dampness, cool blood and stop bleeding, kill insects and detoxify...

AI Technical Summary

Problems solved by technology

At present, Western medicine is the main treatment method, but Western medicine can only improve the symptoms, but cannot control its progress. Long-term use weakens the curative effect and increases the toxicity and side effects. However, Chinese medicine works by regulating the overall condition of the body, with mild drug properties and less toxic side effects.

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