A kind of absorbable rapid hemostasis material and preparation method thereof

Abstract

The invention discloses an absorbable rapid bleeding stopping material and a preparation method thereof. The material comprises medicine carrying calcium alginate porous microspheres, oyster shell powder and sodium carboxymethylcellulose. The medicine carrying calcium alginate porous microspheres and the oyster shell powder have the following two functions: firstly, the medicine carrying calcium alginate porous microspheres and the oyster shell powder serve as a molecular sieve, and can rapidly absorb the water in blood when making contact with the blood, so that visible components in the blood can be rapidly concentrated; secondly, the medicine carrying calcium alginate porous microspheres and the oyster shell powder can release a large number of calcium ions for acting on blood coagulation factors which are concentrated on the material surface, blood coagulation is accelerated, bleeding stopping time is shortened, and the amount of bleeding is reduced. The adopted materials are natural macromolecule polysaccharide and inorganic salt, and the characteristics of good biocompatibility, biodegradability, safety, non-toxicity, absorbability, bleeding stopping ability and the like are achieved. The preparation process is simple, the medicine can be released continuously and steadily within a certain period of time, and the absorbable rapid bleeding stopping material can bring great benefits to the medical field and the society.

Description

Technical field

[0001] The invention belongs to the field of biomedical materials, and specifically relates to an absorbable rapid hemostatic material and a preparation method thereof. Background technique

[0002] At present, the local hemostatic materials used clinically mainly include hemostatic gauze, hemostatic fiber, hemostatic bandage and so on. Since none of these materials are absorbed by the tissue, the hemostasis time is longer and the hemostatic effect is poor. Adhesion to the wound is easy to occur, and the wound is easy to be infected. It is not uncommon to see cases of death due to inability to stop bleeding in time and wound infection. Quick and effective hemostasis can not only relieve the suffering of the injured, but even save a person's life at a critical moment. Some new domestic hemostatic products such as chitosan hemostatic paste, gelatin sponge, collagen sponge hemostatic paste, etc., these products still have poor adhesion to wounds, some have narrow s...

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