4 results about "Time to hemostasis" patented technology

This invention relates to a two-component cross-linked oxidized nanocellulose spray hemostatic gel, its preparation method, and its application, belonging to the field of biomedical materials. Addressing the problems of weak adhesion, insufficient mechanical properties, and biocompatibility risks in existing hemostatic materials, this invention introduces aldehyde groups using sodium periodate to prepare an adhesive component (TOCN-CHO), and simultaneously modifies the carboxyl groups of TOCN with lysine to create a cross-linking component (TOCN-Lys). After the two components are sprayed and mixed, the aldehyde groups of TOCN-CHO bind to the amino groups on the tissue surface to achieve wound sealing. Simultaneously, the amino groups of TOCN-Lys form a Schiff base cross-linking network in situ with the aldehyde groups of TOCN-CHO, enhancing mechanical strength while eliminating aldehyde toxicity. The gel retains shear-thinning properties and can be sprayed. Animal experiments show that the hemostasis time is reduced to 28 seconds. It also exhibits biodegradability and renewability, effectively solving the problem of synergistic optimization of adhesion, mechanical strength, and biocompatibility, making it suitable for emergency hemostasis and surgical scenarios.

This invention provides a chitosan hemostatic material for rapid arterial hemostasis, its preparation process, and its applications, relating to the field of medical technology. The chitosan hemostatic material prepared by this invention can significantly shorten hemostasis time, maintain stable adhesion to the wound surface even under the impact of arterial blood flow, and is not easily detached, exhibiting strong wet adhesion and erosion resistance. The chitosan hemostatic material prepared by this invention not only improves the mechanical strength of the material but also provides more bioactive sites, activating intrinsic coagulation pathways and platelet aggregation, thereby improving hemostasis efficiency and showing significant advantages in emergency applications for arterial bleeding. The chitosan hemostatic material prepared by this invention combines rapid coagulation and stable hemostasis, and has good biocompatibility, controllable degradation, reduced inflammatory response, and high safety. The porous structure of the chitosan hemostatic material prepared by this invention is beneficial for tissue repair, does not adhere to other tissues, promotes healing, and has promising application prospects.

The present application relates to the field of clinical medical technology, in particular to an intelligent hemostasis system and method; the present application collects blood pressure, heart rate, hemostasis pressure, patient body data and patient wound data through a hemostasis device, and constructs a hemostasis time-pressure prediction model through a differential evolution algorithm and a WaveNet model, so as to realize prediction of a relationship curve between hemostasis pressure and hemostasis time; through the relationship curve, the hemostasis device can adjust the pressure applied by the hemostasis device as needed, so as to avoid problems such as excessive hemostasis pressure of a tourniquet, excessive hemostasis time leading to necrosis of a limb or a local part under pressure, and poor hemostasis caused by too small pressure in a war injury treatment process.

This utility model discloses an arterial hemostat, which includes a pressure plate, a fixing component, a hemostatic component, and a coagulation-promoting layer. The pressure plate and the fixing component form a receiving space. The hemostatic component is mounted on the pressure plate, and a coagulation-promoting layer is provided at one end of the hemostatic component facing the receiving space. By adjusting the hemostatic component, the coagulation-promoting layer is brought closer to the patient's puncture site to apply pressure and stop bleeding at the puncture site. This utility model solves the problem of long compression hemostasis time after arterial puncture by providing a coagulation-promoting layer at the adjustment part.