Application of piroctone compound to preparation of health care products for preventing oral mucosa diseases

Abstract

The invention discloses an application of a piroctone compound to preparation of health care products for preventing oral mucosa diseases. It is found that the compound can be used for preparing the health care products for preventing the oral mucosa diseases like recurrent oral ulceration, oral lichen planus, oral erythroplakia, oral leukoplakia, thrush and geographic tongues, and is high in activity and good in prevention effect.

Description

technical field [0001] The invention belongs to the field of health products, and in particular relates to the use of piroctone compounds in the preparation of health products for preventing oral mucosal diseases. Background technique [0002] Oral mucosal diseases refer to diseases that occur in the oral mucosa and soft tissues other than tumors, including oral ulcers, oral lichen planus, oral erythema, oral leukoplakia, thrush, geographic tongue, etc. Among them, oral ulcers, also known as "oral sores", are superficial ulcers that occur on the oral mucosa. The size can range from rice grains to soybeans, and they are round or oval. Recurrent oral ulcer, ROU, also known as Recurrent aphthous ulcers) is one of them, which has the characteristics of periodicity, recurrence and self-limitation, and is prone to occur on the lips, cheeks, tongue margins, etc., and severe cases often The pain is unbearable, so that the patient has trouble sleeping and eating, and the prevalence ...

AI Technical Summary

Problems solved by technology

The curative effect of local treatment is not very clear, some are between effective and ineffective, the healing is slow, and recurrence is easy after healing

(2) Systemic treatment: For example, according to the theory of traditional Chinese medicine, treatment based on syndrome differentiation has a certain curative effect, but the effect is slow and relapse treatment is ineffective; or immunosuppressants such as thalidomide (reactin) (Muriel Hello, MD, Se'bastien Barbarot, MD, Sylvie Bastuji-Garin, MD, PhD, Jean Revuz, MD, and Olivier Chosidow, MD, PhD. Use of Thalidomide for Severe Recurrent Aphthous Stomatitis: A Multicenter Cohort Analysis Medicine. Volume 89, Number 3, May 2010, 176-182 ), prednisone, dexamethasone, etc., but the side effects are relatively large and the onset of effect is slow; or immunomodulators and boosters are used for treatment

However, there is no report on the use of piroctone and its ethanolamine salt for the prevention of oral mucosal diseases

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