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Drug composition for treating cancer, drug kit and application

The technology of a composition and a kit is applied in the field of pharmaceutical compositions for the treatment of cancer, which can solve the problems of frequent loose stools, lack of Pulsatilla japonica, inability to achieve therapeutic effects, etc. quality effect

Inactive Publication Date: 2017-05-10
徐修山
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] However, large doses can cause loss of appetite, loose stools and more frequent reactions
At present, there is still a lack of compatible prescriptions for Pulsatillae, and the simple use of Pulsatilla and its extracts still cannot achieve a good therapeutic effect

Method used

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  • Drug composition for treating cancer, drug kit and application
  • Drug composition for treating cancer, drug kit and application
  • Drug composition for treating cancer, drug kit and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The decocting of embodiment 1 pharmaceutical composition

[0029] According to the formula described in Table 1, the traditional Chinese medicines of each group were obtained. Unless otherwise stated, all traditional Chinese medicines were purchased from Tong Ren Tang and were final decoction pieces. Sucrose and other test materials were purchased from local supermarkets.

[0030] In a preferred aspect of the present invention, the pharmaceutical composition consists of 4 parts by weight of Pulsatilla chinensis, 6 parts of Prunella vulgaris and 8 parts of seaweed.

[0031] In a preferred aspect of the present invention, the pharmaceutical composition consists of 5 parts by weight of Pulsatilla chinensis, 6 parts of Prunella vulgaris and 8 parts of seaweed.

[0032] Table 1: Traditional Chinese medicine formulas of each test group and control group

[0033]

[0034] "Sea Artemisia" and "Hijiki" in the table refer to dry weight.

[0035] Among them, the control gro...

Embodiment 2

[0037] Embodiment 2 The effect of the medicament of the present invention on lymphoma mice

[0038] The human Burkitt lymphoma cell line Daudi was injected into mice through the tail vein to explore the establishment of a mouse model of lymphoma. The specific test method can be found in "Chinese Journal of Cancer", 2009, 28(2): 217-220. Using this method, 8 groups of test mice were obtained, 6 in each group, all of which were ten-week-old female mice (injected at six-week-old and used after four weeks). A course of treatment (15 days) of medication was carried out to the above mice. The way of administration is to use a syringe to perform oral perfusion feeding on the mice, once every morning at 09:00 and 21:00 respectively.

[0039]Before and after the treatment, the body weight of the mice was measured respectively, and after the drug-taking treatment period of the mice was over, the mice were killed and their formed lymphomas were surgically removed, and the fresh lymphom...

Embodiment 3

[0047] Embodiment 3: Effect of the medicament of the present invention on brain tumor mice

[0048] NHG-1 mice (nude mice bearing human brain tumors) were used to study the effects of the agents of the present invention on brain tumor mice. The establishment method of the mouse can be found in the pathological and immunohistochemical characteristics of the human brain glioma cell line nude mouse xenograft model NHG-1, Journal of Clinical and Experimental Pathology, 1986 (1). Using this method, 8 groups of test mice were obtained, 6 in each group, all of which were ten-week-old female mice, all of which were purchased from Junke Biotechnology Co., Ltd. The way of administration is to use a syringe to perform oral perfusion feeding on the mice, once every morning at 09:00 and 21:00 respectively.

[0049] Before and after the treatment, the body weight of the mice was measured respectively, and after the treatment period of the mice was over, the mice were killed and their forme...

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Abstract

The invention provides a drug composition for treating cancer, a drug kit and application. The drug composition is composed of, by weight, 4-40 parts of root of Chinese pulsatilla, 5-7 parts of prunella vulgaris and 5-9 parts of algae. The cancer is chosen from lymph node cancer, lymph cancer and brain tumor. The drug composition has the advantages that drug ingredients are pure natural, thereby being harmless to human body, free of side effect and free of damage to internal organs of the human body. The drug composition can effectively reduce tumor size and increase body weight of patients and is conducive to improving living quality and treatment prognosis of the patients.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical composition, a pharmaceutical kit and application for treating cancer. Background technique [0002] 1. Lymphoma [0003] Malignant lymphoma, also known as "lymphoma", is a malignant tumor that originates in lymph nodes or other lymphoid tissues. It is one of the ten most common malignant tumors in my country. The disease is more common in middle-aged and young people, and there are more male patients than females. The disease can be divided into Hodgkin's disease and non-Hodgkin's lymphoma according to its different cellular components. The degree of malignancy varies, and it is caused by the malignant proliferation of the lymphoid-histiocytic system, which mostly occurs in the cervical lymph nodes. [0004] The manifestation of malignant lymphoma is mainly swollen lymph nodes on the body. It is not painful or itchy in the early stage, so...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K45/00A61P35/00A23L33/00
CPCA61K36/71A23V2002/00A61K36/02A61K36/536A61K45/00A61K2300/00A23V2200/308A23V2250/21A23V2250/208
Inventor 徐修山
Owner 徐修山
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