Baicalin-aluminum dry suspension for treating pigling diarrhoea

A technology of dry suspension of baicalin aluminum, which is applied in the field of preparation of dry suspension for piglets, can solve problems such as food safety hazards, drug residues, unsuitable traditional Chinese veterinary drugs, etc., and achieve drug resistance and stable quality , significant effect

Active Publication Date: 2017-05-17
WUHAN POLYTECHNIC UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the absorption degree of baicalein aluminum in animals is far greater than that of baicalin aluminum, which is likely to cause drug residues and bring

Method used

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  • Baicalin-aluminum dry suspension for treating pigling diarrhoea
  • Baicalin-aluminum dry suspension for treating pigling diarrhoea

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Embodiment 1: the preparation of a kind of baicalin aluminum dry suspension

[0047] Preparation of baicalin aluminum dry extract: ① Weigh 30 kg of Scutellaria baicalensis pieces, soak them in 50% ethanol solution with 8 times the volume of the medicinal material (ie 240 L) at 65°C for 1.5h, and collect the filtrate; then use 6 times the volume of the medicinal material ( Soak 180L) in 50% ethanol solution for 1.5h, and collect the filtrate; ② Collect the two extraction filtrates together, concentrate and recover ethanol at 40°C, and stop the concentration when the volume of the remaining liquid medicine is about half of that before concentration. Collect the liquid medicine; ③After the temperature of the liquid medicine reaches 60°C, slowly add 41L of saturated alum solution (8% alum according to the quality of the medicinal material) into the liquid medicine after the temperature of the liquid medicine reaches 60°C, and stir continuously, heat to fully react for 15 min...

Embodiment 2

[0054] Embodiment 2: the preparation of a kind of baicalin aluminum dry suspension

[0055] The preparation of baicalin aluminum dry extract is the same as in Example 1

[0056] Prescription: active ingredient (baicalin aluminum dry extract) 211.5g, xanthan gum 2.25g, aspartame 22.5g, lactose 213.75g.

[0057] The preparation method is as follows:

[0058] (1) Precisely weigh the active ingredients of the prescription amount and pass through a 150-mesh sieve after being pulverized by a universal pulverizer;

[0059] Preparation method (2)-(4) is the same as embodiment 1

Embodiment 3

[0060] Embodiment 3: the preparation of a kind of baicalin aluminum dry suspension

[0061] The preparation of baicalin aluminum dry extract is the same as in Example 1

[0062] Prescription: active ingredient (baicalin aluminum dry extract) 211.5g, xanthan gum 2.25g, aspartame 22.5g, lactose 213.75g.

[0063] The preparation method is as follows:

[0064] (1) Precisely weigh the active ingredients of the prescription amount and pass through a 100-mesh sieve after being pulverized by a universal pulverizer;

[0065] Preparation method (2)-(4) is the same as embodiment 1

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Abstract

The invention provides a baicalin-aluminum dry suspension for treating pigling diarrhoea. Baicalin as an active component is extracted from radix scutellariae and is processed to form an aluminum salt, and the aluminum salt and reasonable auxiliary materials are mixed to form a veterinary pharmaceutical preparation. The baicalin-aluminum dry suspension comprises, by weight, 200-500 parts of an aluminum salt active component containing 50% of baicalin-aluminum, 2-10 parts of a suspending aid, 20-100 parts of a corrigent, and 390-750 parts of a filler. The baicalin-aluminum dry suspension is suitable for pigling before and after weaning, has remarkable effects, can replace the same kind of antibiotics, prevents resistance to drugs, prevents toxic or side effects caused by antibiotics and antibiotic residues and is beneficial to animal and human health.

Description

technical field [0001] The invention belongs to the field of veterinary medicine technology or animal husbandry, and relates to a preparation method and application of a dry suspension for piglets. Background technique [0002] China is the world's largest pig-raising country, and pork occupies the first place in human meat consumption. Piglet rearing is an important stage in the pig raising process. At present, the occurrence and mortality of piglets with diarrhea before and after weaning are high. Although some piglets did not die after diarrhea, the growth rate in the later stage was obviously slower, which caused a lot of economic losses to farmers. The most common way to treat diarrhea is to use antibacterial drugs. Due to the severe drug resistance of bacteria at present, the treatment effect is poor and drug residues are likely to be caused. Traditional Chinese medicine has the advantages of multiple functions and low price, and it is more and more used in veterinary...

Claims

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Application Information

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IPC IPC(8): A61K9/14A61K9/16A61K31/7048A61K47/36A61P1/12A61P31/04
Inventor 邱银生刘宇叶纯吴仲元付书林熊江林
Owner WUHAN POLYTECHNIC UNIVERSITY
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