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Resurrection hormone composition capable of improving filling fat survival rate and reducing fat fibration and calcification

A survival rate and filling technology, applied in the field of bioengineering, can solve problems such as difficulty in dispensing lipoactivin, difficult cost and technical conditions, and complex life characteristics, so as to reduce the possibility and severity of rejection and improve Effects on Survival, Likelihood and Severity Reduction

Inactive Publication Date: 2017-05-31
티안지우안
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the most prominent method of research is to use lipoactivin to improve the survival rate of cell transplantation. The difficulty of this technology is that it is difficult to configure the corresponding lipoactivin, and the situation of each recipient is inconsistent, so it is difficult to effectively configure according to the actual situation. Fat resurrection has good sex, and even if it can effectively configure fat resurrection according to the actual situation of the receptor, it is difficult to realize. The main reason is that the vital characteristics of the actual receptor are complex. , need to do a lot of testing and analysis work, the cost and technical conditions are difficult to apply in large quantities in actual production and life

Method used

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  • Resurrection hormone composition capable of improving filling fat survival rate and reducing fat fibration and calcification
  • Resurrection hormone composition capable of improving filling fat survival rate and reducing fat fibration and calcification
  • Resurrection hormone composition capable of improving filling fat survival rate and reducing fat fibration and calcification

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A resurrection formula that can improve the survival rate of filling fat and reduce fat fibrosis and calcification is composed of the following raw materials in parts by weight:

[0023] 20 parts of mother cells from the recipient type, 20 parts of glucose base solution, 10 parts of recombinant human interleukin-II, 12 parts of cytokines, 1 part of human pH regulator, 5 parts of amino acids, human acidic fibroblast factor rh- 6 parts of aFGF, 4 parts of cell growth stimulating activity GRO / MGSA, 0.5 part of lysozyme.

[0024] According to the above technical solution, the mother cells obtained from the recipient type have cell functional structures such as organelles removed, and only the cell fluid is retained.

[0025] According to the above technical solution, the concentration of the glucose base solution is 0.100 mol / L.

[0026] According to the above technical solution, the recombinant human interleukin-II includes any three or four of α1b, α2a, ξ, ω, μ, τ, and κ...

Embodiment 2

[0031] A resurrection formula that can improve the survival rate of filling fat and reduce fat fibrosis and calcification is composed of the following raw materials in parts by weight:

[0032] 23 parts of mother cells from the recipient type, 22 parts of glucose base solution, 12 parts of recombinant human interleukin-II, 13 parts of cytokines, 1.5 parts of human pH regulator, 6.5 parts of amino acids, human acidic fibroblast factor rh- 8 parts of aFGF, 6 parts of cell growth stimulating activity GRO / MGSA, 0.75 parts of lytic enzyme.

[0033] According to the above technical solution, the mother cells obtained from the recipient type have cell functional structures such as organelles removed, and only the cell fluid is retained.

[0034] According to the above technical solution, the concentration of the glucose base solution is 0.180 mol / L.

[0035] According to the above technical solution, the recombinant human interleukin-II includes any three or four of α1b, α2a, ξ, ω, ...

Embodiment 3

[0040] A resurrection formula that can improve the survival rate of filling fat and reduce fat fibrosis and calcification is composed of the following raw materials in parts by weight:

[0041] 26 parts of mother cells from the recipient type, 24 parts of glucose base solution, 14 parts of recombinant human interleukin-II, 14 parts of cytokines, 2 parts of human pH regulator, 8 parts of amino acids, human acidic fibroblast factor rh- 9 parts of aFGF, 8 parts of cell growth stimulating activity GRO / MGSA, 1 part of lysozyme.

[0042] According to the above technical solution, the mother cells obtained from the recipient type have cell functional structures such as organelles removed, and only the cell fluid is retained.

[0043] According to the above technical solution, the concentration of the glucose base solution is 0.260 mol / L.

[0044] According to the above technical solution, the recombinant human interleukin-II includes any three or four of α1b, α2a, ξ, ω, μ, τ, and κ1...

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Abstract

The invention discloses a resurrection hormone composition capable of improving filling fat survival rate and reducing fat fibration and calcification. The resurrection hormone composition comprises, by weight, 20-26 parts of mother cells from receptor types, 20-24 parts of glucose base solution, 10-14 parts of recombinant human interleukin-II, 12-14 parts of cell factors, 1-2 parts of human PH (potential of hydrogen) regulators, 5-8 parts of amino acid, 6-9 parts of rh-a FGF (recombinant human-acidic fibroblast growth factors), 4-8 parts of cell growth stimulating activities GRO / MGSA and 0.5-1 part of lytic enzyme. Cells of types of same receptors serve as basic materials, cell organelles and the like in the basic materials are removed, cell sap is reserved, corresponding cell factors for assisting vital movement of the receptors are added, most of needed additives are from cell receptors, possibilities and seriousness of rejection reaction can be greatly reduced to some extent, special matching according to life characteristics of actual receptors can be omitted, production cost and technical requirements are effectively reduced, the application range of fat resurrection hormone is widened, and practicability of the fat resurrection hormone is improved.

Description

technical field [0001] The invention relates to the technical field of bioengineering, in particular to a resurrection formula that can improve the survival rate of filling fat and reduce fat fibrosis and calcification. Background technique [0002] Cell transplantation is the transplantation of healthy cells into the patient's body to repair or replace damaged cells or tissues, thereby achieving the purpose of healing. Cell transplantation has a wide range of treatments, and can generally treat nervous system diseases, immune system diseases, and other medical and surgical diseases, and has a very wide application prospect. However, in this actual transplantation work, due to the self-protection and cell differentiation of the human immune system, the transplanted cells will often be inactivated, thus failing to achieve the corresponding biological medical purpose. The main reason for the rate. [0003] At present, the main method to improve the survival rate of cell tran...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N5/071
CPCC12N5/0602C12N2500/32C12N2500/34C12N2501/113C12N2501/20C12N2501/2302C12N2501/70
Inventor 田娟
Owner 티안지우안
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