Haematococcus pluvialis solid dispersion, and preparation method and applications thereof

Abstract

The invention provides a haematococcus pluvialis solid dispersion, and a preparation method and applications thereof. The provided haematococcus pluvialis solid dispersion is composed of three phases namely dry algae residues prepared by subjecting haematococcus pluvialis to CO2 supercritical extraction, microencapsulated powder prepared by subjecting the haematococcus pluvialis extract obtained by CO2 supercritical extraction to microencapsulation, and a solid dispersion carrier. The invention also provides a preparation method and applications of the haematococcus pluvialis solid dispersion. The experiment results show that the astaxanthin stability, bioavailability, and anti-oxidation activity of the haematococcus pluvialis solid dispersion are obviously better than those of the cell-wall-broken haematococcus pluvialis, CO2 supercritical extract, and microencapsulated powder prepared by subjecting the CO2 supercritical extraction extract to microencapsulation.

Description

technical field [0001] The invention relates to a solid dispersion of Haematococcus pluvialis, its preparation method and application. [0002] technical background [0003] Haematococcus Agardh is a single-celled green algae produced in freshwater, rich in carotenoids, protein, insoluble dietary fiber, vitamin B 2 , Vitamin B 12 , niacin, calcium, magnesium, zinc and other nutrients, is vitamin B 1 , Vitamin B 6 origin of. In addition, during the growth process, affected by extreme environmental influences (such as ammonia deficiency, strong light, drastic temperature changes and other unsuitable conditions), the algae will transform from moving vegetative cells into thick-walled static spores, and at the same time accumulate a large amount of red shrimp green It is known as the "source" and "concentrate" of natural astaxanthin. [0004] Astaxanthin, also known as "astaxanthin", is a carotenoid. Chemical name: 3,3"-dihydroxy-4,4"-diketo-β-carotene, molecular formula C ...

AI Technical Summary

Problems solved by technology

At present, the production process of astaxanthin by Haematococcus pluvialis culture stress is not mature in China, and its content is in an uncontrollable state;

[0009] (3) Astaxanthin has very unstable physical and chemical properties due to its super antioxidant properties, and is easily oxidatively exhausted by the influence of temperature and light

Astaxanthin in the unbroken Haematococcus pluvialis (powder) exists in the chlamydospores in various forms such as free, monoester, diester, polyester, etc. and remains relatively stable, but it is difficult to be extracted, developed, application, the use value is extremely low; Haematococcus pluvialis (powder) and its extracts after the wall-breaking process increase the chance of astaxanthin in contact with the outside world. Rapid oxidative exhaustion during processing, transportation, and storage (generally exhausted within days or weeks), greatly restricting its development and application;

[0010] (4) Astaxanthin, as a fat-soluble β-carotene, is difficult to be absorbed and utilized when eaten directly, and its bioavailability is not high. It needs a large dose (≥12mg / day) to show its health care function

The effective utilization rate of resources is low, resulting in waste of resources

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