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Antidiarrheic drug compound containing montmorillonite and medicinal activated carbon, preparation method and application

A technology of montmorillonite and activated carbon, which is applied in the direction of drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems of incomplete intestinal obstruction and the dosage should not be too much, and achieve good clinical application prospects and low side effects. Small, good antidiarrheal effect

Inactive Publication Date: 2017-07-07
成都维恒医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the amount of montmorillonite should not be too much. If the amount is too much, adverse reactions such as constipation or even incomplete intestinal obstruction may occur.

Method used

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  • Antidiarrheic drug compound containing montmorillonite and medicinal activated carbon, preparation method and application
  • Antidiarrheic drug compound containing montmorillonite and medicinal activated carbon, preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1 Preparation of the pharmaceutical composition of the present invention

[0021] 1. Raw materials: montmorillonite 2000g, medicinal activated carbon 20g, carboxymethyl cellulose 50g, water.

[0022] 2. Preparation method

[0023] (1) Micronize the montmorillonite raw material and pass through a 200-mesh sieve;

[0024] (2) Evenly add 2000 g of sieved montmorillonite and 20 g of medicinal activated carbon (the particle size of medicinal activated carbon is 50-75 μm) into 6000 ml of purified water, settle naturally, soak for 30 minutes, and stir until the mixed solution is in a uniform state;

[0025] (2) Weigh 50g of CMC, add purified water at 60-80°C, stir to fully dissolve, then add to the above mixture in batches under stirring;

[0026] (3) Stir and heat the above liquid to boil for 10 minutes, and add purified water to 10000ml during cooling to room temperature.

[0027] (4) Dispensing, 120ml per bottle.

Embodiment 2

[0028] Embodiment 2 Preparation of the pharmaceutical composition of the present invention

[0029] 1. Raw materials: montmorillonite 200g, medicinal activated carbon 200g, carboxymethyl cellulose 50g, water.

[0030] 2. Preparation method

[0031] (1) Micronize the montmorillonite raw material and pass through a 200-mesh sieve;

[0032] (2) Evenly add 200 g of sieved montmorillonite and 200 g of medicinal activated carbon (the particle size of medicinal activated carbon is 50-75 μm) into 6000 ml of purified water, settle naturally, soak for 30 minutes, and stir until the mixed solution is in a uniform state;

[0033] (2) Weigh 50g of CMC, add purified water at 60-80°C, stir to fully dissolve, then add to the above mixture in batches under stirring;

[0034] (3) Stir and heat the above liquid to boil for 10 minutes, and add purified water to 10000ml during cooling to room temperature.

[0035] (4) Dispensing, 120ml per bottle.

Embodiment 3

[0036] Embodiment 3 Preparation of the pharmaceutical composition of the present invention

[0037] 1. Raw materials: montmorillonite 2000g, medicinal activated carbon 2g, carboxymethyl cellulose 50g, water.

[0038] 2. Preparation method

[0039] (1) Micronize the montmorillonite raw material and pass through a 200-mesh sieve;

[0040] (2) Evenly add 2000 g of sieved montmorillonite and 2 g of medicinal activated carbon (the particle size of medicinal activated carbon is 50-75 μm) into 6000 ml of purified water, settle naturally, soak for 30 minutes, and stir until the mixed solution is in a uniform state;

[0041] (2) Weigh 50g of CMC, add purified water at 60-80°C, stir to fully dissolve, then add to the above mixture in batches under stirring;

[0042] (3) Stir and heat the above liquid to boil for 10 minutes, and add purified water to 10000ml during cooling to room temperature.

[0043] (4) Dispensing, 120ml per bottle.

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Abstract

The invention discloses an antidiarrheic drug compound containing montmorillonite and medicinal activated carbon, a preparation method and an application. The antidiarrheic drug compound disclosed by the invention is a preparation prepared from crude drugs including montmorillonite and medicinal activated carbon at weight ratio of (0.1:100)-(100:0.1). The invention also provides a drug combination of montmorillonite and medicinal activated carbon. The drug combination disclosed by the invention is effective in treating diarrhea, has slight side effect, can supply a new choice for clinically treating diarrhea and has an excellent clinical application prospect.

Description

technical field [0001] The invention relates to an antidiarrheal pharmaceutical composition containing montmorillonite and medicinal activated carbon, a preparation method and application thereof. Background technique [0002] Animal diarrhea has always been a large class of diseases that plague the breeding industry and the pet industry. It can occur at various stages of animal growth and occurs in all seasons; there are stress diarrhea, microbial diarrhea, nutritional diarrhea, etc. Diarrhea will directly cause animals to suffer from diarrhea. The absorption and utilization of nutrients are reduced, the physical fitness of animals is reduced, the immune function is weakened, and the resistance to epidemic diseases is weakened, which leads to the occurrence of secondary diseases and even death, resulting in great economic losses. Therefore, it has become a research hotspot in veterinary medicine to seek high-efficiency, low-toxic, safe, and "universal therapeutic effect" dr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/06A61K33/44A61P1/12
CPCA61K33/06A61K33/44A61K2300/00
Inventor 沈芃曹晓红陈洪杜全胜卢福周锡建
Owner 成都维恒医药科技有限公司
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