Vitamin composition for precision nutrition suitable for middle-aged and old crowds
A vitamin and composition technology, applied in the field of vitamin composition, can solve the problems of unpredictable health effects, lack of pertinence, and low content of each element
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Embodiment 1
[0034] Embodiment 1: tablet preparation (1000 pieces amount) of nutritional supplement of the present invention
[0035] formula:
[0036]
[0037]
[0038] Preparation method: take povidone K30 and prepare an adhesive with 50% ethanol solution, then add vitamin A and vitamin K into the adhesive, stir evenly, and set aside. Separately take vitamin B12, sucralose and pregelatinized starch, mix and sieve, then add milk essence, carboxymethyl starch sodium, dextrin and mix, add the prepared soft material containing vitamin A and vitamin K binder, 24 Granulate with a mesh sieve, dry at 55°C for 2 hours, granulate with a 24 mesh sieve, add magnesium stearate, mix, and tablet. The coating premix is formulated into a solution, and the plain tablet is coated to obtain the tablet of the nutritional supplement of the present invention.
Embodiment 2
[0039] Embodiment 2: the soft capsule preparation (1000 amount) of health food of the present invention
[0040] formula:
[0041]
[0042] Preparation method: add beeswax to soybean oil, heat at 50°C to dissolve the beeswax, place it at room temperature, add vitamin A, vitamin K, and vitamin B12 to soybean oil to make a suspension, and set aside. In addition, gelatin, purified water, caramel color, and parabens are prepared into a glue solution, and the prepared suspension is pressed into pills by a pill press to make soft capsules. After shaping, pill washing and drying, it is prepared Obtain the soft capsule of health food of the present invention.
[0043] The pharmaceutical composition prepared in Example 2 was taken for safety toxicology evaluation and pharmacodynamic test.
[0044] Acute Toxicity: Get the contents of the capsules made in Example 2, give 20 rats (half male and half male) at a dose of 5g / kg, give them by intragastric administration at a volume of 40mL / ...
Embodiment 3
[0055] Embodiment 3: preparation of pharmaceutical composition hard capsules of the present invention (1000 grains amount)
[0056] formula:
[0057]
[0058] Preparation method: mix vitamin B12 with 20% microcrystalline cellulose, sieve, then add vitamin K and vitamin A to mix, mix the obtained raw material mixture with the remaining amount of microcrystalline cellulose in equal increments, then add lactose, hard Magnesium fatty acid is mixed, then filled with a full-automatic capsule filling machine, and polished to obtain the hard capsule of the pharmaceutical composition of the present invention.
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