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Hymenoleana nana extract and application thereof

A technology of extracting and decocting, which is applied in the field of plant processing and Kurumuti processing and preparation, to achieve the effect of lowering triglycerides, wide practicability and development value, and lowering blood sugar

Inactive Publication Date: 2017-08-18
新疆智库丝路知识产权大数据中心(有限公司)
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing technology fails to use scientific and technological means to provide applicable technical solutions to fully develop the potential medicinal value of Kurumuti

Method used

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  • Hymenoleana nana extract and application thereof
  • Hymenoleana nana extract and application thereof
  • Hymenoleana nana extract and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Example 1: The preparation method of the extract of Kurumuti

[0030] (1) Pulverizing and sieving: select qualified Kurumuti plants, clean and dry their roots, stems and leaves and pulverize them, and pass through an 80-mesh sieve to obtain Kurumuti powder;

[0031](2) Extraction: put a certain amount of Kurumu extract powder into 3-10 times the amount of purified water for decoction, the decoction time is 40 minutes to 60 minutes, and the number of decoctions is 2 times to 4 times;

[0032] (3) Filtration: filter the obtained liquid through centrifugation or membrane filtration, and take the supernatant for subsequent use;

[0033] (4) Concentration and drying: Concentrate the supernatant under normal pressure to 1 / 5 of the original volume, and then dry to obtain the extract of Kurumuti. The drying temperature is 40°C-60°C.

Embodiment 2

[0034] Embodiment two: Orthogonal experiment optimization preparation method of the present invention

[0035] Weigh multiple groups of 1000g Kurumu extract powder respectively, put them into purified water for decoction according to the method of the present invention, centrifugally filter the decoction obtained, and collect the filtrate; concentrate the filtrate under reduced pressure to 1 / 5 of the original volume, Drying is carried out by far-infrared radiation drying equipment, and the quality of the obtained Kurumuti extract is weighed after the drying is completed.

[0036] A single factor experiment was designed to explore the effects of different decoction time, decoction times and drying temperature on the extraction amount of kulumu. On the basis of the single factor experiment, a three-factor and three-level orthogonal experiment was carried out. The factors and levels of the orthogonal experiment are shown in Table 1.

[0037] Table 1: Orthogonal test factor and l...

Embodiment 3

[0043] Example 3: Preparation of the extract of Kurumuti

[0044] Select qualified Kurumu extract plants to dry and crush, pass through a 80-mesh sieve to obtain Kurum extract powder for later use, weigh 50kg of Kurum extract powder, put it into 8 times the amount of purified water and decoct 3 times, decoct The temperature is 50°C, the decoction time is 60 minutes, the resulting decoction is centrifugally filtered, and the filtrate is collected; the filtrate is concentrated under reduced pressure to 1 / 5 of the original volume, and dried by far-infrared radiation drying equipment at a drying temperature of 40 ℃, after the drying is completed, the extract of 26kg brown Kurumuti is obtained.

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Abstract

The invention discloses a hymenoleana nana extract and an application thereof. The hymenoleana nana extract is obtained through a series of steps of crushing of roots, stems and leaves of hymenoleana nana, sieving, extraction, filtration, concentration and drying. The invention further discloses preparation of hymenoleana nana microcapsules and lozenges from the hymenoleana nana extract with a representative encapsulation coating technology. The hymenoleana nana extract as well as the microcapsules and lozenges prepared from the hymenoleana nana extract can significantly reduce blood glucose for a hyperglycemia mouse model and reduce blood pressure of laboratory rats as compared with untreated hymenoleana nana, are proved to have effects of reducing triglyceride and improving high-density lipoprotein in clinical experiments and have wide practicability and development value.

Description

technical field [0001] The present invention mainly relates to the field of plant processing, in particular, the present invention relates to the field of Kurumuti processing and preparation. Background technique [0002] Kurumuti, the scientific name of Dwarf celery, is a unique medicinal plant in the Pamirs of Xinjiang. Its stems, leaves, and roots can be used as medicine. It is commonly used by the local Tajik people. It may prevent diabetes, high blood pressure, and coronary heart disease. Common food and medicinal materials such as cardiovascular diseases. However, as a plant medicinal material that may have good efficacy in preventing and treating cardiovascular diseases, there is still no processing method that can significantly improve the efficacy, and it cannot be industrialized. There is no specific technical solution to verify and use its potential efficacy. The undeveloped state cannot meet the needs of scientific analysis and utilization. [0003] Metabolic s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/23A61K9/50A61K9/20A61K47/69A61P9/12A61P3/10A61P3/06
CPCA61K9/2059A61K9/5036A61K36/23A61K2236/15A61K2236/331A61K2236/51A61K2236/39
Inventor 闫论王盼安伟伟李春
Owner 新疆智库丝路知识产权大数据中心(有限公司)
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