Sisheng collateral dredging plaster and preparation method thereof

A preparation method and a technology for plastering plaster, which are applied in the directions of pharmaceutical formulations, medical preparations without active ingredients, and medical preparations containing active ingredients, etc., can solve the problem that the prescription lacks the theoretical guidance of traditional Chinese medicine, the drug load is small, and the curative effect is poor. and other problems, to achieve the effect of wide applicability, significant curative effect and significant curative effect

Active Publication Date: 2017-08-22
陕西中医药大学附属医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional Chinese medicine plasters still have technical defects such as low drug loading, lack of theoretical guidance in traditional Chinese medicine, and poor curative effect.

Method used

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  • Sisheng collateral dredging plaster and preparation method thereof
  • Sisheng collateral dredging plaster and preparation method thereof
  • Sisheng collateral dredging plaster and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] By weight, get 30-60 parts of Shierqi respectively, 30-50 parts of Flying Centipede Seven, 30-60 parts of raw Southern Star, 30-50 parts of raw pinellia, 6-15 parts of Rhizoma Chuanxiong, 10-15 parts of cloves, 3-6 parts of ephedra, and make superfine powder according to the conventional method; mix 8-12 parts of raw rehmannia with distilled water at a solid-liquid ratio of 1: (8-12) g / ml, and mix well , heating the temperature to 90°C-100°C, heating and extracting at this temperature for 1-2 hours each time, extracting 2-3 times, combining the extracts, concentrating the extracts, drying and pulverizing; mixing the above two kinds of medicinal powders Obtain mixed medicinal powder evenly; soak and fry 20-40 parts of peppercorns and peppers with sesame oil, filter out the medicinal residues; press medical pressure-sensitive adhesive and pepper oil per (20Kg-25kg): (0.8L-1.2L ) ratio, put it in an oil bath, control the temperature between 250°C and 260°C to dissolve, the...

Embodiment 2

[0038]According to the weight ratio, get 45-55 parts of Shierqi respectively, 45-50 parts of Flying Centipede Seven, 30-45 parts of raw Southern Star, 30-45 parts of raw pinellia, 10-15 parts of Rhizoma Chuanxiong, 10-12 parts of cloves, 4-5 parts of ephedra, made into superfine powder according to the conventional method; mix 9-11 parts of raw rehmannia with distilled water at a solid-liquid ratio of 1: (8-12) g / ml, and mix well , heating the temperature to 90°C-100°C, heating and extracting at this temperature for 1-2 hours each time, extracting 2-3 times, combining the extracts, concentrating the extracts, drying and pulverizing; mixing the above two kinds of medicinal powders Obtain mixed medicinal powder evenly; soak and fry 25-35 parts of peppercorns with sesame oil, filter out medicinal residues; use medical pressure-sensitive adhesive and peppercorn oil at a ratio of (20Kg-25kg):(0.8L-1.2L) , put it in an oil bath, control the temperature between 250°C and 260°C to dis...

Embodiment 3

[0040] According to the ratio of parts by weight, get Shierqi 50kg, Flying Centipede Seven 50kg, raw Nanxing 30kg, raw Pinellia 30kg, Chuanxiong 10kg, cloves 10kg, ephedra 5kg, make superfine powder earlier according to conventional methods; 10 parts of raw rehmannia The solid-liquid ratio with distilled water is 1: (8-12) g / ml, mix evenly, heat to 90°C-100°C, heat and extract at this temperature for 1-2 hours each time, extract 2-3 times, Combine the extracts, concentrate the extracts, dry and pulverize; mix the above two medicinal powders evenly to obtain a mixed medicinal powder; soak and fry 30 kg of peppercorns in sesame oil, filter out the medicinal residues; press the medical pressure-sensitive adhesive and pepper oil Per (20Kg-25kg): (0.8L-1.2L) ratio, put it in an oil bath, control the temperature between 250°C-260°C to dissolve, then add the mixed powder, stir and grind repeatedly for 60 minutes, until completely mixed Finally, add 3kg borneol after melting with 99% ...

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Abstract

The invention discloses Sisheng collateral dredging plaster, prepared by the following steps: smashing and sieving crude drugs of radix trillium tschonoskii, rhizome of bigflower ladyslipper, raw root of arisaema, raw rhizoma pinelliae, rhizome of chuanxiong, flos caryophylli and herba ephedrae, so as to obtain ultra-fine powder; uniformly mixing a crude drug of dried rehamnnia root and distilled water, heating to 95 DEG C, performing heating extraction for 2 to 3 times, combining extracting solutions and concentrating, drying and smashing; uniformly mixing drug powder; soaking a crude drug of sichuanese peppercorn with sesame oil, frying, and filtering to remove dregs; putting medicinal pressure-sensitive adhesive and sichuanese peppercorn oil into an oil bath pan at the temperature of 25 DEG C according to a ratio of 22Kg to 1L, and dissolving; adding the drug powder, repeatedly stirring and grinding for 60min, after mixing completely uniformly, adding borneol, and stirring again to obtain the plaster. The prescription is formed by combining 'qi-blood muscle-bone syndrome differentiation' of traditional Chinese medicine with 'a four-beam eight-column theory' of folk herbalists, has remarkable curative effects of treating diseases such as protrusion of lumbar intervertebral disc, osteoarthritis, synovitis, scapulohumeral periarthritis and external humeral epicondylitis, is high in safety, and is very suitable for a pain-suffered patient to use.

Description

technical field [0001] The invention relates to a plaster, in particular to an analgesic plaster. Background technique [0002] The traditional plaster first appeared in Ge Hong's "Elbow Reserve Emergency Prescription" (about 315 AD) in the Jin Dynasty. It was made from decoction pieces of Chinese medicine soaked in sesame oil and then boiled with Huangdan. It was developed by Tang Sun Simiao, Ming Li Shizhen and other doctors. It was not until Wu Shangxian in the Qing Dynasty wrote the monograph "Theoretical Parallel Essays" on plasters, which marked that traditional plasters had been widely used in clinical practice for various diseases. At present, some traditional plasters such as dog skin plaster can still be seen on the market. However, the drug's safety has been widely questioned because of its lead-containing formulation. [0003] Patent CN201110001832.1 discloses a plaster for external use made of pure traditional Chinese medicine and its preparation method, provi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/70A61P19/08A61P19/02A61P29/00A61K31/045
CPCA61K9/7023A61K31/045A61K36/17A61K36/236A61K36/25A61K36/61A61K36/758A61K36/804A61K36/8884A61K36/8888A61K36/896A61K47/10A61K2236/331A61K2236/39A61K2300/00
Inventor 李引刚刘艳平
Owner 陕西中医药大学附属医院
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