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Compound Cortex Phellodendri gel for treating child eczema and preparation method

A technology of compound Phellodendron phellodendri and Phellodendron phellodendri, applied in the field of medicine, can solve the problems such as insufficient curative effect, short wound surface retention time, secondary infection, etc., and achieve the effect of prolonging the drug retention time, long duration of drug effect, and not polluting clothes.

Active Publication Date: 2017-09-26
山东汉方生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the dosage form of compound Phellodendron phellodendron liquid varnish is mainly external liquid preparation, which has a short residence time on the wound surface and cannot give full play to the curative effect. In clinical practice, sterile gauze is used for wet compress, which is inconvenient to use and easily causes secondary infection

Method used

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  • Compound Cortex Phellodendri gel for treating child eczema and preparation method
  • Compound Cortex Phellodendri gel for treating child eczema and preparation method
  • Compound Cortex Phellodendri gel for treating child eczema and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0078] 1. Product: a compound phellodendron gel for treating eczema in children

[0079] 2. Materials and methods

[0080] 2.1 Instruments

[0081] pH meter, electric thermostatic water bath, refrigerator, oven, electronic balance, etc.

[0082] 2.2 Materials and reagents

[0083] Forsythia: Forsythia Forsythia suspensa (Thunb.) Vahl dried fruit.

[0084] Phellodendron chinensis: the dried bark of the rutaceae Phellodendron chinense Schneid.

[0085] Honeysuckle: It is the dried flower buds or the first blooming flowers of the honeysuckle Lonicera japonica Thunb.

[0086] Dandelion: It is the dry whole grass of Taraxacum mongolicum Hand.-Mazz., Taraxacum borealisinense Kitam. or several plants of the same genus.

[0087] Centipede: The dried body of the centipede Scolopendra subspinipes mutilans L.Koch.

[0088] The above medicinal materials are in compliance with the provisions of each medicinal material in the 2015 edition of the Chinese Pharmacopoeia.

[0089] Trieth...

Embodiment 2

[0145] Formula: Forsythia 70 parts, Treats 35 parts, Honeysuckle 35 parts, Dandelion 35 parts, Centipede 2.1 parts, Carbomer 1 part, Transcutol P 5 parts.

[0146] Preparation:

[0147] (1) weigh the five Chinese medicines in the prescription by weight components, add water to decoct and extract three times, the first time is 1 hour, the second time is 45 minutes, and the third time is 30 minutes;

[0148] (2) the decoctions were combined, filtered, and the filtrate was concentrated to a clear paste with a relative density of 1.10 to 1.15 (measured at 50°C);

[0149] (3) adding ethanol to make the ethanol content reach 70%, standing for 24 hours, filtering, and concentrating the filtrate under reduced pressure until there is no alcohol smell, to obtain compound phellodendron ethanol precipitation and fluid extract.

[0150] (4) Take the liquid extract after alcohol precipitation, add 4 times the amount of purified water, heat in a water bath at 80° C., filter the precipitate ...

Embodiment 3

[0155] Formula: Forsythia 80 parts, Treats 40 parts, Honeysuckle 40 parts, Dandelion 40 parts, Centipede 2.4 parts, Carbomer 3 parts, Transcutol P 10 parts.

[0156] The preparation method is the same as that of Example 2.

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Abstract

The invention provides compound Cortex Phellodendri gel for treating child eczema and a preparation method. The compound Cortex Phellodendri gel for treating child eczema consists of the following raw herbal medicines in parts by weight: 70-90 parts of Fructus Forsythiae, 35-45 parts of Cortex Phellodendri, 35-45 parts of honeysuckle, 35-45 parts of dandelion, 2.1-2.7 parts of Scolopendra, 1-6 parts of carbomer, 5-15 parts of Transcutol P, 2-5 parts of triethanolamine, 10-30 parts of glycerol and 0.1-0.5 part of potassium sorbate. By the compound Cortex Phellodendri gel, the shortcomings that the residence time of compound Cortex Phellodendri liquid liniment on wound is short, and the wound needs to be covered with gauze can be overcome to a great extent; compared with other domestic and international like products, the compound Cortex Phellodendri gel has considerable resource advantages and technical advantages; and used Chinese herbal medicines are common medicinal materials, auxiliary materials are common pharmaceutic adjuvants, and the supply quality can be guaranteed. The traditional Chinese medicine extracting technology is mainly used, and is organically combined to an alcohol precipitation and water precipitation separation technology, a gel preparation process and the like, effective ingredients of traditional Chinese medicines and the pharmaceutic adjuvants are combined organically, and the efficacy is played fully. The compound Cortex Phellodendri gel for treating child eczema has considerable social benefit and economic benefit.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a compound Phellodendron gelatin for treating children's eczema and a preparation method. Background technique [0002] Children are a special group in the population. They are in the stage of gradual growth and development to maturity. They are divided into 8 different stages due to their different ages. However, children at different ages have different frequently-occurring diseases, and children's skin diseases are different from adults. Features. In my country, the policy of prenatal and postnatal care is implemented, and parents are encouraged to have only one child, and they are more concerned about children. Children's skin and children's skin diseases have gradually been paid attention to, and children's eczema and atopic dermatitis are common chronic and inflammatory diseases in children. Sexual skin disease. With the development of my country's national economy and ...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/06A61K47/32A61K47/10A61K47/18A61P17/00A61K35/648
CPCA61K9/06A61K35/648A61K36/288A61K36/355A61K36/634A61K36/756A61K47/10A61K47/18A61K47/32A61K2236/331A61K2236/51A61K2236/53A61K2300/00
Inventor 秦承雪
Owner 山东汉方生物科技有限公司
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