Drug for treatment of acute and chronic bacterial infection caused by sensitive bacteria and preparation method thereof
A bacterial infection, acute and chronic technology, applied in the field of medicine, can solve the problems of not being able to exert the drug effect quickly, alleviating the symptoms of chronic patients, low bioavailability, etc. Effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0066] A preparation method for preparing dispersible tablets for the treatment of acute and chronic bacterial infections caused by sensitive bacteria, comprising the steps of:
[0067] T1: Weigh the following components by weight: Erythromycin 2000g, sodium alginate 1000g, hydroxypropyl methylcellulose 800g, dextran 3000g, sodium carboxymethyl starch 600g, sodium lauryl sulfate 600g 100g of micropowder silica gel, passed through a 100-mesh sieve, and set aside;
[0068] T2: Preparation of Etoerythromycin inclusion complex: Dissolve Etoerythromycin in 4000g of absolute ethanol to make Etoerythromycin absolute ethanol liquid, take sodium alginate and put it in a batching tank, add 10000g of water and heat to 45°C to make it Dissolve to obtain sodium alginate solution, slowly add Etoerythromycin absolute ethanol solution into the sodium alginate solution, stir while adding, the stirring speed is 50rpm, keep stirring at 45°C for 4h, put it at room temperature and set aside Place...
Embodiment 2
[0075] A preparation method for preparing dispersible tablets for the treatment of acute and chronic bacterial infections caused by sensitive bacteria, comprising the steps of:
[0076] T1: Weigh the following components by weight: Erythromycin 2000g, sodium alginate 1400g, hydroxypropyl methylcellulose 1000g, dextran 3800g, sodium carboxymethyl starch 1000g, sodium lauryl sulfate 800g 1. Micropowder silica gel 140g, passed through a 100-mesh sieve, set aside;
[0077] T2: Preparation of Etoerythromycin Inclusion Compound: Dissolve Etoerythromycin in 6000g of absolute ethanol to make Etoerythromycin absolute ethanol liquid, take sodium alginate and put it in a batching tank, add 14000g of water and heat to 65°C to make it Dissolve to obtain sodium alginate solution, slowly add Etoerythromycin anhydrous ethanol solution into sodium alginate solution, stir while adding, stirring speed is 100rpm, keep stirring at 65°C for 2h, put it at room temperature and then set aside Place i...
Embodiment 3
[0084] A preparation method for preparing dispersible tablets for the treatment of acute and chronic bacterial infections caused by sensitive bacteria, comprising the steps of:
[0085] T1: Weigh the following components by weight: Erythromycin 2000g, sodium alginate 1200g, hydroxypropyl methylcellulose 900g, dextran 3400g, sodium carboxymethyl starch 800g, sodium lauryl sulfate 700g 120g of micropowder silica gel, passed through a 100-mesh sieve, and set aside;
[0086] T2: Preparation of Etoerythromycin inclusion compound: Dissolve Etoerythromycin in 5000g of absolute ethanol to make Etoerythromycin absolute ethanol liquid, take sodium alginate and put it in a batching tank, add 12000g of water and heat to 55°C to make it Dissolve to obtain sodium alginate solution, slowly add Etoerythromycin anhydrous ethanol solution into sodium alginate solution, stir while adding, stirring speed is 80rpm, keep stirring at 55°C for 3h, put it at room temperature and place Place it at 6°C...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com