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Apparatus and method for non-invasively determining the concentration of an analyte

An analyte and concentration technology, applied in applications, temperature sensors, medical science, etc., to achieve high accuracy and avoid skin burns

Active Publication Date: 2017-11-07
RADIOMETER BASEL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] This prior art generally has the disadvantage that there is an energy flow between the sensor and the patient's skin tissue due to the thermal gradient between the sensor and the skin tissue

Method used

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  • Apparatus and method for non-invasively determining the concentration of an analyte
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  • Apparatus and method for non-invasively determining the concentration of an analyte

Examples

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Embodiment Construction

[0057] figure 1 Shown for non-invasive measurement of pCO 2 Schematic block diagram of an example of the sensor head of the device. The sensor head 101 includes a sensor housing 119 made of electrically insulating material such as polyphenylene oxide (PPO), in which a first heat conducting plate 105 and a second heat conducting plate 120 are respectively provided. The plates 105 and 120 may be made of silver or gold or materials that have similar or at least suitable thermal conductivity and do not interfere with chemical analysis. The thermal conductive plate can be embedded in the epoxy resin casting 121 and fixed by the epoxy resin casting. The epoxy resin casting fills the gap between the plate and the housing, and is formed between the thermal conductive plates 105 and 120 and sandwiched between the two The thermal insulation layer 104 between the thermally conductive plates. The first thermally conductive plate 105 defines a measurement surface of the sensor head, which ...

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PUM

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Abstract

The invention discloses A sensor and an apparatus for non-invasive measurement of an analyte concentration, the apparatus comprising: a first thermal sensor (106) operable to determine a temperature indicative of a temperature at a location on a skin (122) of a subject, an analyte sensor (103) operable to generate a measurement indicative of a concentration of the analyte, a heater (109); a controller (216) operable to receive a temperature signal from at least the first thermal sensor and to adjust the heater to maintain a thermal equilibrium at said location on the skin; and a processor (213) configured to convert the measurement to a calculated analyte concentration value at a predetermined temperature.

Description

Technical field [0001] The embodiments of the devices and methods disclosed herein relate to the field of non-invasively measuring the analyte concentration in a subject, and in particular, to the location of the subject’s tissue (such as the subject’s skin), For example, measuring carbon dioxide (CO 2 ) Or the partial pressure of other blood gases. Background technique [0002] The partial pressure of blood gas (such as carbon dioxide (pCO) 2 ) Or oxygen (pO 2 )) Performing non-invasive measurements has been described in many publications as a method available in a variety of clinical situations. [0003] In prior art sensors, as described for example in US 7,474,908 or US 5,425,868, the gas is measured with a sensor applied to the skin surface, which sensor is equipped with a heating element for heating the skin area on which the sensor rests. The sensor contact surface is heated to a temperature of about 40°C to 44°C, which leads to local vasodilatation and arterialization of t...

Claims

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Application Information

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IPC IPC(8): A61B5/1477A61B5/1491
CPCA61B5/14542A61B5/1477A61B5/1491A61B2562/0271A61B2562/04
Inventor P-A.吉西杰
Owner RADIOMETER BASEL