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Encapsulation structure and encapsulation method of biochip
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A biochip and packaging structure technology, which is applied in biochemical equipment and methods, biochemical cleaning devices, and microbial determination/inspection, etc., can solve the problems of easy contamination of packaging structures, obstacles in fluid channels, and poor flow stability. Achieve the effect of reducing the probability of contamination, improving stability, and reducing flow resistance
Active Publication Date: 2021-03-19
ZHUHAI CHUANGFEIXIN TECH CO LTD
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[0004] In order to solve the above-mentioned technical problems, the embodiment of the present invention provides a packaging structure and packaging method for biochips to solve the problems of poor flow stability, easy contamination of the packaging structure, and repeated use due to obstacles in the fluid channel introduced by the columnar structure supporting the chip. low efficiency and difficulty in miniaturization, improve the integration of the packaging structure of the biochip, and reduce the cost of the packaging structure
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[0050] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.
[0051] In the following description, a lot of specific details are set forth in order to fully understand the present invention, but the present invention can also be implemented in other ways different from those described here, and those skilled in the art can do it without departing from the meaning of the present invention. By analogy, the present invention is therefore not limited to the specific examples disclosed below.
[0052]As mentioned in the backg...
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Abstract
The invention discloses a biochip packaging structure and method. The packaging structure comprises a first substrate and a second substrate, a wiring layer located on the side, facing the second substrate, of the first substrate, a biochip located on the side, back on to the first substrate, of the wiring layer, a first hydrophobic layer covering the wiring layer and the biochip, and a second hydrophobic layer located on the side, facing the first substrate, of the second substrate. A detection unit is arranged on the surface of the side, back on to the wiring layer, of the biochip, and the detection unit is exposed out of the first hydrophobic layer. The surface of the side, back on to the wiring layer, of the first hydrophobic layer is flush with the surface of the side, back on to the wiring layer, of the detection unit. A fluid channel is formed between the first hydrophobic layer and the second hydrophobic layer. An electric connection area is arranged on the side, back on to the wiring layer, of the biochip. The electric connection area is electrically connected with the wiring layer through a silicon chip channel. The problems that due to the fact that a chip is supported by cylindrical structures, a fluid channel might be blocked, flow smoothness is poor, a packaging structure is prone to pollution, the recycling rate is low, and miniaturization is not easy are solved.
Description
technical field [0001] The invention relates to the field of packaging technology, in particular to a packaging structure and packaging method for a biochip. Background technique [0002] Based on the principle of specific interaction between biomolecules, the biochip integrates the biochemical analysis process on the surface of the chip, so as to realize the high-throughput and rapid detection of DNA, RNA, peptides, proteins and other biological components. High-throughput rapid detection to obtain disease detection results is now widely used in the field of biomedicine, with the characteristics of high-throughput, automation and miniaturization. [0003] Such as figure 1 As shown, in the currently commonly used biochip packaging structure, there are some columnar structures 02 in the fluid channel 01 to support the biochip, which not only increases the resistance of the fluid flow process in the fluid channel 01, which is not conducive to the smooth flow of the fluid, but...
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