Systems and methods for combined vertical/lateral flow blood separation technologies with cotinine detection

A lateral flow, cotinine technology, applied in measurement devices, biological tests, analytical materials, etc., can solve the problems of complicated sampling collection and sample processing

Active Publication Date: 2018-01-19
POLYMER TECH SYST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Current point-of-care or near-patient settings are limited to qualitative testing of urine and saliva, complicating sample collection and sample processing

Method used

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  • Systems and methods for combined vertical/lateral flow blood separation technologies with cotinine detection
  • Systems and methods for combined vertical/lateral flow blood separation technologies with cotinine detection
  • Systems and methods for combined vertical/lateral flow blood separation technologies with cotinine detection

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Embodiment Construction

[0023]Certain terms are used herein for convenience only, and are not to be considered as useful for integrating vertical / lateral flow blood separation techniques with extended scope to achieve point-of-care cotinine Limitations of Embodiments of the Systems and Methods of Detecting Combinations. In the drawings, the same reference numerals are used to denote the same elements throughout the several views.

[0024] Currently, all point-of-care tests for the detection of cotinine, a metabolite of nicotine, are based on oral fluid (saliva) or urine and provide only qualitative or semi-quantitative results. To achieve quantitative results, samples must be sent to a central laboratory for liquid chromatography-tandem mass spectrometry (LC-MS / MS) analysis. These results can often take more than a week, greatly limiting the window of opportunity for education and intervention.

[0025] In one embodiment, the system is capable of quantifying cotinine from whole blood samples in a p...

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PUM

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Abstract

A system for determining a level of cotinine in a sample includes a test strip system configured to receive a sample, the test strip system including a first lateral flow test strip and a second lateral flow test strip, the first and second lateral flow test strips each having an overlapping but non-identical range for cotinine. The system further includes a meter configured to receive the test strip, wherein the meter is configured to read the test strip and detect a level of cotinine.

Description

Background technique [0001] Smoking is the leading cause of preventable death in the United States, according to the Centers for Disease Control and Prevention. The first published study of the harmful health effects of smoking was a retrospective analysis of the smoking habits of lung cancer patients in 1950. The major harmful effects of smoking include, but are not limited to, heart disease, stroke, chronic obstructive pulmonary disease, and many cancers. Although initially attributed to primary smoking activity, the adverse effects on individual health extend to those who are passively exposed to tobacco smoke in the environment. These health consequences of tobacco use substantially increase health care costs. In 2014, the U.S. Department of Health and Human Services released a report entitled "Health Consequences of Smoking-50 Years of Progress-A Report of the Surgeon General", evaluating Economic costs due to lost productivity due to both early mortality and associate...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/00G01N33/558G01N33/94
CPCG01N33/558G01N33/54313G01N33/946G01N33/54387
Inventor K·莫斯科维茨C·戴利C·谢R·李
Owner POLYMER TECH SYST
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