Preparation method for hyaluronic acid-gelatin-banana extract composite microsphere

A technology of hyaluronic acid and composite microspheres, used in the preparation of microspheres, microcapsule preparations, etc., can solve the problems of polyphenol biological titer limitation, loss of physiological activity, loss of activity, etc., and achieve good loading and sustained release. The effect of low material cost and strong water retention

Inactive Publication Date: 2018-02-23
TONGLING JIAYAN ECOLOGICAL AGRI DEV
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AI Technical Summary

Benefits of technology

This patented technology involves making small amounts of balsa wood pulp that contain different types of substances like sugars or other compounds found naturally within plants called lignans (lucan). These substance help make paper stronger by forming tiny particles when mixed together during papermaking processes. By adding these chemicals after cooking, this new type of plant fiber becomes more durably resistant against wear caused by friction forces on its surface. Additionally, there're also some benefits associated with processing bananas containing certain nutrients: they provide antioxic properties through their flavorings, while being able to absorb harmful gases released over time.

Problems solved by technology

This patented technical problem addressed in this patents relates to improving the effectiveness or absorbability of certain compounds found naturally occurring within plants called flavonoids that can help prevent damage from harmful chemical reactions caused during harvesting processes like burning rice straw without losing any usefulness when used alone.

Method used

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Embodiment Construction

[0016] A preparation method of hyaluronic acid-gelatin-banana extract composite microspheres, characterized in that it comprises the following steps:

[0017] (1) Wash and dry 35 parts by weight of banana peels, crush them, add 35 parts by weight of water to soak for 25 minutes, filter, add the filtrate to 30 parts by weight of aqueous solution, ultrasonically treat for 25 minutes, and filter 3 times through a 200-mesh screen Finally, after adding 25 parts by weight of water to the filtrate, use an ultrafiltration device to carry out ultrafiltration, and the ultrafiltration rear gain is moved to a sealed container, stored in a refrigerator, and used for later use;

[0018] (2) After freeze-drying the product obtained in step (2), pulverize and pour 35 parts by weight of hyaluronic acid and 15 parts by weight of gelatin into 40 parts by weight of water, stir magnetically at room temperature for 3 hours, and then ultrasonicate for 35 minutes Put the mixture in the refrigerator t...

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Abstract

The invention discloses a preparation method for a hyaluronic acid-gelatin-banana extract composite microsphere. The preparation method comprises the following steps: washing banana skin and then preparing a homogenate from the banana skin; carrying out filtering, adding water into the obtained filtrate, and then successively carrying out ultrasonic treatment, filtering with a screen, ultrafiltration, hermetic cooling, freeze-drying and crushing; then dispersing the obtained substance, hyaluronic acid and gelatin in water and successively carrying out ultrasonic treatment, freezing and unfreezing; forming an oil phase from liquid paraffin and span-80 and dropwise adding an unfrozen solution into the oil phase; and adding a cross-linking agent, i.e., glutaraldehyde, and successively carrying out centrifugation, precipitation and washing so as to obtain the hyaluronic acid-gelatin-banana extract composite microsphere. The preparation method of the invention is simple in process and low in the cost for the raw materials. The prepared composite microsphere has biodegradability, strong water retention performance, and good loading and controlled-release effect.

Description

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Claims

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Application Information

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Owner TONGLING JIAYAN ECOLOGICAL AGRI DEV
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