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Preparation technology of rhizoma coptidis extract enteric-coated pellets

A preparation process, the technology of Coptidis rhizome, applied in the preparation of enteric-coated pellets of traditional Chinese medicine, the preparation process of enteric-coated pellets of Coptidis extract enteric-coated pellets" belongs to the field of traditional Chinese medicine preparations, and can solve the problems of destroying active ingredients and affecting the efficacy of drugs, etc.

Inactive Publication Date: 2018-03-06
WUHU TIANCHENG PUYANG TRADITIONAL CHINESE MEDICINE TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the hydrochloric acid in the gastric juice will often destroy the active ingredients of the drug, thus affecting the efficacy of the drug.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0005] Facility Example 1

[0006] Pour the decoction pieces of Coptis chinensis into 8 times the weight of boiling water, keep boiling for 10 minutes, filter while hot with a 200-mesh sieve, and obtain the filtrate for later use. Add 5 times the weight of the dregs to decoct twice, keep boiling for 60 minutes after each boil, and filter while hot. The three filtrates were combined and concentrated under reduced pressure to a concentrate with a relative density of 1.05. On the other hand, add the macroporous resin to 8 times the weight of deionized water, soak it at 50°C for 12 hours, stir it from time to time, and change the water every 2 hours. Then add 5 times the weight of 60% edible alcohol to the drained macroporous resin, and soak it twice at room temperature for 2 hours each time. Put the macroporous resin soaked in alcohol into a vacuum rotary evaporating drier to recover alcohol, then transfer it to a vacuum drying oven at 50°C for 6 hours under reduced pressure, p...

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PUM

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Abstract

The invention discloses a preparation technology of rhizoma coptidis extract enteric-coated pellets. The preparation technology mainly comprises the following steps: extracting and concentrating traditional Chinese medicine rhizoma coptidis; then treating macroporous resin; uniformly mixing a prepared rhizoma coptidis concentrated extracting solution with the macroporous resin and drying to obtainpellet cores of the enteric-coated pellets; carrying out fluidized bed coating on the pellet cores by utilizing acrylic resin and drying to obtain the rhizoma coptidis extract enteric-coated pellets.The rhizoma coptidis extract enteric-coated pellets prepared by the preparation technology can be used for preventing stomach qi from being injured by the bitter cold of the rhizoma coptidis; meanwhile, the concentration of effective components in intestines is increased. The technology for preparing the enteric-coated pellets is simple and has very great economic value.

Description

technical field [0001] The "preparation process of enteric-coated pellets of Coptis chinensis extract" of the present invention belongs to the field of traditional Chinese medicine preparations, especially the field of traditional Chinese medicine enteric-coated pellets. Background technique [0002] Traditional oral preparations of traditional Chinese medicine, such as pills, powders, granules, tablets, capsules and liquid preparations, mostly disintegrate or dissolve in the stomach, irritating the gastric mucosa and affecting the patient's appetite. Especially Coptis chinensis and other traditional Chinese medicines with cold and cold properties, long-term use can hurt the stomach qi, affect the function of the spleen and stomach, and damage people's righteousness. In addition, the hydrochloric acid in the gastric juice often destroys the active ingredients of the drug, thereby affecting the efficacy of the drug. The intestine is the main site of drug absorption. In the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61K9/50A61K47/32A61P31/04A61P29/00
CPCA61K36/718A61K9/5026A61K2236/331A61K2236/39A61K2236/51
Inventor 黄竹青
Owner WUHU TIANCHENG PUYANG TRADITIONAL CHINESE MEDICINE TECH CO LTD