4 results about "Double balloon catheter" patented technology

A “localizable” systemic gene therapy system is provided substantially increasing the transfection efficiency of the gene vectors into targeted tissue cells and substantially reducing the escape of the gene vectors from the targeted tissue volume, such as would waste the vectors, promote undesired immune reactions, and / or incur prohibitive costs for the required dose of gene-containing virus vectors. In this regard, the invention provides a means to simultaneously achieve local cell membrane permeability for virus vector transport and gene-containing vector injection in a portion of a vascularized organ. It includes a double-balloon catheter that create a finite contained volume in a blood vessel for the introduction of vectors with reduced loss along with a percutaneously inserted needle electrode providing increased cell membrane permeability for virus vector transport of the cells by creating an electric field in the same location where the vectors are injected.

The application relates to the technical field of medical supplies and particularly discloses a double-layer balloon catheter which comprises a catheter seat, a catheter, a first balloon body and a second balloon body, the catheter is connected with the catheter seat, the first balloon body and the second balloon body are coaxially nested to form a double-layer balloon body structure which is sleeved outside the catheter, the first balloon body forms a first cavity, the second balloon body is located at the outer layer, the second balloon body and the first balloon body form a second cavity, the catheter seat is provided with a guide channel, a first communicating nozzle and a second communicating nozzle; gas can be introduced into the first cavity through the first communicating nozzle to simultaneously expand the first balloon body and the second balloon body, so that the folds and dead angles are eliminated, the folding and forming of the product are facilitated, and when the double-layer balloon catheter is used clinically, filling liquid can be introduced into the second cavity through the second communicating nozzle, the second cavity can be extruded when being filled, the residual gas in the first cavity is discharged through the first communicating nozzle, the filling liquid can completely and dead-angle-free fill the second cavity, and the developing blind area under X-ray perspective is completely eliminated.

A "localizable" systemic gene therapy system is provided substantially increasing the transfection efficiency of the gene vectors into targeted tissue cells and substantially reducing the escape of the gene vectors from the targeted tissue volume, such as would waste the vectors, promote undesired immune reactions, and / or incur prohibitive costs for the required dose of gene-containing virus vectors. In this regard, the invention provides a means to simultaneously achieve local cell membrane permeability for virus vector transport and gene-containing vector injection in a portion of a vascularized organ. It includes a double-balloon catheter that create a finite contained volume in a blood vessel for the introduction of vectors with reduced loss along with a percutaneously inserted needle electrode providing increased cell membrane permeability for virus vector transport of the cells by creating an electric field in the same location where the vectors are injected.

The utility model discloses a double-balloon catheter with a directional puncture indication function, which relates to the technical field of puncture catheters and specifically comprises a catheter body provided with an inner catheter and an outer catheter, a columnar balloon arranged on the outer catheter and positioned at the front end of the outer catheter, and a spherical balloon arranged on the outer catheter and positioned in the middle or in the front of the columnar balloon, a first air pipe communicated with the columnar balloon and a second air pipe communicated with the spherical balloon are arranged in the outer pipe. The columnar balloon and the spherical balloon are arranged on the tube body provided with the inner tube and the outer tube, the columnar balloon is arranged on the spherical balloon in a sleeving mode, a space under the intima or in the plaque is created through the columnar balloon, the circle center of the two-dimensional projection of the spherical balloon is used as the directional indication direction of the reverse guide wire, and therefore the guide wire can be stably guided. The problem that the guide wire punctures outside a blood vessel due to the fact that the puncture part of the guide wire is poor and the advancing direction of the guide wire is wrong is avoided, the puncture accuracy of the guide wire is effectively improved, and the problem that the guide wire punctures outside the blood vessel is effectively reduced.