Active composition for treating chronic urticaria based on multi-target intervention and preparation method of active composition

A kind of technology of chronic urticaria and composition, applied in the field of medicine, can solve the problems of easy recurrence of disease, complicated preparation process of medicament and the like

Active Publication Date: 2018-03-06
深圳敬中堂科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the therapeutic agents provided in the prior art can effectively treat chronic urticaria to a certain extent, there are common problems that the preparation process of the agents is complicated and the disease is prone to relapse.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0049] The invention provides the preparation method of described active composition comprising the following steps:

[0050] The active composition is obtained by mixing garlic extract, citric acid, ginseng extract and mineral elements.

[0051] In the present invention, the source of the garlic extract is not particularly limited, and conventional extraction methods in the art can be used. In the embodiment of the present invention, the preparation method of the garlic extract comprises the following steps:

[0052] Garlic peeled→cleaned→add water and crushed→enzymolysis→steam distillation→oil-water separation→garlic oil→electromagnetic microwave treatment to extract allicin.

[0053] In the present invention, in the process of adding water and mashing, the mass of water added per kilogram of garlic is preferably 2kg-4kg.

[0054] In the present invention, the type of enzyme for enzymatic hydrolysis is preferably sucrase. The activity of the enzyme for enzymolysis is pref...

Embodiment 1

[0075] Mineral elements include metal elements of the following mass: 4kg of iron, 4kg of calcium, 1kg of zinc, 0.012kg of copper, 10kg of magnesium, 0.05kg of vanadium, 0.008kg of strontium and 0.032kg of cobalt. Select copper gluconate, calcium gluconate, zinc gluconate, magnesium sulfate, metavanadate, cobalamin, ferrous gluconate and strontium metasilicate as the raw materials of the above metal elements, calculate and weigh according to the mass of the above metal elements The corresponding raw materials are measured and mixed to obtain mineral elements.

[0076] The preparation method of the garlic extract comprises the following steps: garlic peeling→cleaning→adding water and crushing→enzymolysis→water steam distillation→oil-water separation→garlic oil→300MHz-300000MHz electromagnetic microwave assisted leaching of allicin.

[0077] In the embodiment of the present invention, the preparation method of the ginseng extract comprises the following steps:

[0078] Process ...

Embodiment 2

[0083] Mineral elements include metal elements in the following mass fractions: 6kg of iron, 2kg of calcium, 3kg of zinc, 0.008kg of copper, 14kg of magnesium, 0.04kg of vanadium, 0.012kg of strontium and 0.028kg of cobalt. Select copper citrate, calcium citrate, zinc glycinate, magnesium chloride, metavanadate, cobalamin, ferrous fumarate and strontium metasilicate as raw materials for the above metal elements, calculate and weigh according to the mass of the above metal elements The corresponding raw materials are mixed to obtain mineral elements.

[0084] The preparation method of the garlic extract comprises the following steps: garlic peeling→cleaning→adding water and crushing→enzymolysis→water steam distillation→oil-water separation→garlic oil→300MHz-300000MHz electromagnetic microwave assisted leaching of allicin.

[0085] In the embodiment of the present invention, the preparation method of the ginseng extract comprises the following steps:

[0086] Process ginseng in...

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Abstract

The invention provides an active composition for treating chronic urticaria based on multi-target intervention and a preparation method of the active composition and belongs to the technical field ofmedicines. The active composition for treating chronic urticaria based on multi-target intervention contains the following components: garlic extract, citric acid, ginseng extract and mineral elements, wherein the total mass content of thioether, ester and thioglycoside molecules in the garlic extract is 1-90%; the molecular mass content of a panoxadiol structure contained in the ginseng extract is 1-90%; and the mineral elements include the following metallic elements: iron, calcium, zinc, copper, magnesium, vanadium, strontium and cobalt. The mineral elements serving as a metal protein assembly are capable of enabling chronic urticaria related genes to normally achieve the catalytic effect, and the garlic extract, the citric acid and the ginseng extract serve as a molecular group structure, so that the chronic urticaria related genes are normal. Therefore, the effect of treating the chronic urticaria is achieved.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an active composition for treating chronic urticaria based on multi-target intervention and a preparation method thereof. Background technique [0002] Urticaria is commonly known as "welt", "wheal". Modern medicine believes that urticaria is a localized edema reaction caused by the expansion and permeability of skin, mucous membranes, and small blood vessels under the action of various factors. 15% to 20% of people have at least one episode of urticaria in their lifetime. Urticaria can be divided into acute and chronic urticaria, and those that last for more than 1 to 3 months are called chronic urticaria. Urticaria is a worldwide disease that occurs at any age, with a high or low incidence depending on the cause. [0003] Chronic urticaria, if it occurs in the larynx and bronchi of the respiratory tract, it will lead to recurrent laryngeal edema, throat congesti...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61P17/00A61K31/194A61K33/26A61K33/06A61K33/30A61K33/34A61K33/24A61K33/00
Inventor 乌林奇
Owner 深圳敬中堂科技有限公司
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