34 results about "Cholinergic urticaria" patented technology

The invention discloses a medicine composition for treating chronic urticaria in the technical field of traditional Chinese medicine development and utilization. The medicine composition is prepared from the following raw materials in parts by weight: 20 to 40 parts of cortex dictamni, 10 to 14 parts of cortex moutan, 20 to 28 parts of radix rehmanniae, 8 to 10 parts of radix paeoniae rubra, 20 to 28 parts of flowers of Chinese scholartree, 8 to 10 parts of radix sileris, 10 to 20 parts of radix sophorae flavescentis, 8 to 10 parts of earthworms, 10 to 14 parts of cicada shells and 5 to 8 parts of liquorice roots. The medicine composition for treating the chronic urticaria is prepared from natural traditional Chinese medicine ingredients, can be taken after being decorated with water, and can also be made into lozenges, chewable tablets, effervescent tablets or granules and the like; a good effect can be achieved on the treatment of chronic urticaria; the radical cure can be realized without recurrence; the traditional Chinese medicine composition is safe to take and does not have toxic and side effects.

The invention relates to a traditional Chinese medicine decoction for treating chronic urticaria. The traditional Chinese medicine decoction is prepared from 4 to 7 parts of cassia twigs, 4 to 7 parts of ephedra, 4 to 7 parts of almonds, 4 to 7 parts of liquorice roots, 12 to 18 parts of astragalus membranaceus, 8 to 12 parts of ledebouriella seseloides wolff, 8 to 12 parts of white atractylodes rhizomes, 13 to 18 parts of white peony roots, 7 to 13 parts of Chinese angelica, 4 to 7 parts of ligusticum wallichii, 4 to 7 parts of dried gingers, 4 to 7 parts of Chinese dates and 15 to 25 parts of poria cocos wolf. The decoction has a good treatment effect on the chronic urticaria, is convenient to take, has no toxic side effects, is safe and reliable and is low in treatment cost.

The invention belongs to the technical field of treatment medicines for urticaria, and specially relates to a pharmaceutical composition for treating acetyl cholinergic urticaria and application of the pharmaceutical composition in preparation of a medicine for preventing or treating the acetyl cholinergic urticaria, aiming at overcoming the shortage that the existing medicine for treating the acetyl cholinergic urticaria has poor treatment effect and cannot act for a long time in the prior art. The pharmaceutical composition for treating or preventing the acetyl cholinergic urticaria consists of levocetirizine and isopropylidene sedoheptuiosan. The pharmaceutical composition shows a good effect on treatment of acetyl cholinergic urticaria and is remarkably worthy of clinical popularization.

The invention discloses a traditional Chinese medicine composition for treating chronic urticaria. The traditional Chinese medicine composition is prepared from the traditional Chinese medicinal materials in parts by weight: 10-20 parts of herba schizonepetae, 10-20 parts of radix sileris, 10-20 parts of pepper, 10-30 parts of radix gentianae, 10-30 parts of periostracum cicada, 20-40 parts of cortex dictamni, 10-20 parts of fructus kochiae, 5-15 parts of coptis roots, 5-15 parts of sophora flowers, 20-40 parts of oldenlandia diffusa, 20-40 parts of semen coicis and 10-20 parts of garter snakes. The traditional Chinese medicine composition has the efficacies of invigorating a spleen for eliminating dampness, clearing away heat and purging pathogenic fire, detoxicating, promoting eruption, dispelling wind and arresting itching, has a significant curative effect in treating chronic urticarial and is reliable in effect, and the ingredients of the traditional Chinese medicine composition are wide in source, and simple and convenient to prepare, and are free from toxic and side effects.

The invention discloses a traditional Chinese medicine formula for treating chronic urticaria. The traditional Chinese medicine is characterized by being prepared from, by weight, 10-15 g of astragalus membranaceus, 10-15 g of fleece flower roots, 10-15 g of rhizoma atractylodis macrocephalae, 10-12 g of angelica sinensis, 10-12 g of cortex dictamni, 10-12 g of common peony roots, 10-12 g of saposhnicovia divaricata, 6-10 g of periostracum cicada, 6-10 g of scorpion and 6-10 g of centipede. By the adoption of the traditional Chinese medicine formula, wheals can be eliminated and pruritus can be stopped after one treatment course for less serious cases, and blotches and pruritus are eliminated after two to three treatment courses for serious cases. The skin scratch test is negative, and blood routine reexamination shows that the number of eosinophilic granulocytes is reduced to be normal.

The invention relates to the field of pharmaceutical formulations, in particular to a traditional Chinese medicine for chronic urticaria. Its technical feature is that the composition of raw materials is calculated by weight percentage: 4-6 burdock seeds, 10-13 honeysuckle flowers, and 8 tribulus terrestris ~11, Duckweed 7~11, Paeoniae Alba 8~10, Nepeta 6~8, Dandelion 4~7, Smilax 6~7, Saponin 8~11, Rehmannia glutinosa 7~10, Codonopsis 6~9, Guizhi 3-5, soak the above 12 raw materials in water, remove the slag after decoction to obtain the filtrate. The invention has the advantages of low cost, high curative effect for treating chronic urticaria, and no toxic and side effects.

The invention provides a single nucleotide polymorphism site of ORAI1 genes of chronic urticaria susceptible patients and a detection agent thereof, and particularly provides a single nucleotide polymorphism site of rs3741595C / T, rs3741596A / G, rs12313273T / C and rs12320930G / T of ORAI1 genes, and the single nucleotide polymorphism site is adopted to detect chronic urticaria and to serve as the drug target for treating chronic urticaria patients. Drugs are applied on this basis, so the efficiency of disease treatment is improved and the living quality of the patients is improved. In addition, the morbidity can be predicted.

The invention discloses a Chinese herbal compound for treating cholinergic urticaria. The Chinese herbal compound comprises a part for oral administration and a part for external use, wherein the part for oral administration is prepared from the following 19 Chinese herbal medicine ingredients in parts by weight: 6-9 parts of ephedra, 6-9 parts of root of red-rooted salvia, 6-9 parts of sophora flavescens, 6-9 parts of common cnidium fruit, 6-9 parts of divaricate saposhnikovia root, 3-5 parts of root bark of shaggy-fruited dittany, 3-5 parts of belvedere fruit, 3-5 parts of longhairy antenoron herb, 3-5 parts of lysimachia christinae hance and the like; and the part for external use is prepared from the following Chinese herbal medicine ingredients in parts by weight: 6-9 parts of flax, 6-9 parts of dried rehamnnia root, 6-9 parts of burnt gardenia, 6-9 parts of siegesbeckia herb, 2-4 parts of lithospermum, 2-4 parts of mint, 2-4 parts of wild chrysanthemum, 2-4 parts of hiraute shiny bugleweed herb, 2-4 parts of castor leaf, 2-4 parts of dyer woad leaf and 5-10 parts of black sesame seed oil. The medicament has the effects of inducing sweat, dispelling exogenous evils, dispelling wind, relieving itching, detoxifying, relaxing the bowels, draining, eliminating pus and the like, is mainly used for treating the cholinergic urticaria and also has an obvious treatment effect on various skin diseases such as various acute and chronic urticaria.

The invention discloses a traditional Chinese medicine composition for treating cholinergic urticaria. The traditional Chinese medicine composition is characterized by being prepared from the following components in parts by weight: 5 to 12 parts of schizonepeta, 5 to 12 parts of radix saposhnikoviae, 3 to 10 parts of periostracum cicada, 5 to 12 parts of cortex phellodendri, 5 to 15 parts of fructus forsythia, 10 to 40 parts of plaster stone, 5 to 15 parts of radix sophorae flavescentis, 5 to 15 parts of cortex dictamni, 3 to 10 parts of rhizoma cimicifugae, 5 to 12 parts of scutellaria baicalensis, 5 to 20 parts of radix rehmanniae, 5 to 15 parts of cortex moutan, and 3 to 8 parts of liquorice; and the components above can be prepared into any one of the forms of decoction, granules, pills or capsules by the general method of a traditional Chinese medicine preparation. The traditional Chinese medicine composition focuses on the optimization of effects of the components on clearing heat and removing toxicity, and dispelling wind and arresting itching, so as to specially treat adverse clinical symptoms of cholinergic urticaria; and with the coordinative action of all the components, the traditional Chinese medicine has the effects of accelerating the adequate eruption of cholinergic urticaria, dispersing and promoting eruption, eliminating wind and relieving convulsion, clearing away heat and drying dampness, nourishing Yin and engendering liquid, balancing internal environment, and particularly reducing hazardous substances in blood, so as to remove toxin from blood to the body surface along with sweat, and as a result, the cholinergic urticaria can be treated completely.

The invention relates to a traditional Chinese medicine composition for treating chronic urticaria. The traditional Chinese medicine composition comprises the following traditional Chinese medicine ingredients in part by weight: 10-40 parts of dried rehmannia root, 10-40 parts of nacre mother of pearl, 10-40 parts of dens draconis, 10-30 parts of root of common peony, 10-30 parts of radix paeoniae alba, 5-20 parts of peach kernel, 10-30 parts of coxtex moutan, 10-40 parts of poria cocos, 5-20 parts of chrysanthemum, 10-30 parts of cortex albiziae, 5-20 parts of smoked plum, 10-40 parts of tribulus terrestris, and 10-40 parts of the root of red-rooted salvia. The traditional Chinese medicine composition has the efficacies of clearing heat, soothing the nerves, promoting blood circulation to remove meridian obstruction, nourishing blood, soothing the liver, nourishing yin, promoting the secretion of saliva or body fluid, and strengthening the spleen and stomach, has an obvious curative effect on treating chronic urticaria, has reliable effects, and has the advantages of wide ingredient medicinal herbs resources, simplicity and convenience in preparation, mild drug properties and no toxic and side effects.

Disclosed are internal drug for treating chronic urticaria and a preparation method thereof. The internal drug is composed of, by mass, 1-3 parts of Chinese Atractylode rhizome, 1-3 parts of Poria cocos, 1-3 parts of white Atractylodes rhizome, 1-3 parts of Schizonepeta herb, 1-3 parts of peony bark, 1-3 parts of Chinese parsnip root, 1-3 parts of tribulus terrestris, 1-3 parts of muscardine cadaver, 1-3 parts of Szechuan lovage rhizome, 1-3 parts of red-rooted Salvia root, 1-3 parts of dragon's bone and 1-3 parts of Scutellaria root. The preparation method includes the following steps: selecting and purchasing Chinese Atractylode rhizome, Poria cocos, white Atractylodes rhizome, Schizonepeta herb, peony bark, Chinese parsnip root, tribulus terrestris, muscardine cadaver, Szechuan lovage rhizome, red-rooted Salvia root, dragon's bone and Scutellaria root which are high in quality, clean and first-class according to a mass part ratio, respectively removing impurities and dust, and sacking and tying for standby use; placing the components in cold boiled water for soaking for half an hour, placing the soaked components and supernatant liquid for soaking the components in a decocting machine, injecting cold boiled water higher than the components by 35mm for first-time decocting for 40 minutes, filtering to obtain drug liquid, injecting slightly warm boiled water higher than the components by 32mm for second-time decocting for 35 minutes, mixing and concentrating to form 1620ml of 50% traditional Chinese medicine liquid, bagging and sealing, and placing the traditional Chinese medicine liquid in a refrigerator for preservation and standby use.

The invention discloses a medicine for treating chronic urticaria. The medicine is composed of an active ingredient and a medically acceptable auxiliary, wherein the active ingredient is made of the following raw materials in percentage by weight: Radix Astragali 7%-9%, Atractylodes macrocephala 4% to 5%, Poria 11% to 13%, black snake 5% to 7%, centipede 1% to 3%, scorpion 1% to 2%, ground beetle 1% to 2%, habitat 4% to 6% %, Ephedra 4%-6%, Scrophulariaceae 4%-6%, Gypsum 4%-6%, Forging Keel 15%-17%, Sophora flavescens 4%-6%, Kochia chinensis 4%-6%, white 4% to 6% of fresh skin, 4% to 6% of salvia miltiorrhiza, and 7% to 9% of rhizome of imperina. The medicine described in the present invention can be oral preparations such as granules, capsules or tablets, and has the advantages of quick improvement of symptoms and low recurrence rate through clinical verification.

The invention relates to a traditional Chinese medicine used for treating chronic urticaria. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 15 parts of fructus kochiae scopariae, 6 parts of divaricate saposhnikovia roots, 10 parts of periostracum cicadae, 3 parts of mint and 9 parts of potentilla discolor. Urticaria is thought to be externally caused by attack of outer pathogenic wind which is blocked by skin and contained in blood, and internally caused by accumulated heat, which cannot be vented inwards or drained outwards and is accumulated in skin, in stomach and intestines, and is caused by both blood heat and pathogenic wind. Preferably, symptoms are treated through cooling and itching relieving, and the root cause is eliminated through blood clearing and wind dispelling. Therefore, the traditional Chinese medicine is made.

The invention belongs to the technical field of treatment medicines for urticaria, and specially relates to a pharmaceutical composition for treating acetyl cholinergic urticaria and application of the pharmaceutical composition in preparation of a medicine for preventing or treating the acetyl cholinergic urticaria, aiming at overcoming the shortage that the existing medicine for treating the acetyl cholinergic urticaria has poor treatment effect and cannot act for a long time in the prior art. The pharmaceutical composition for treating or preventing the acetyl cholinergic urticaria consists of levocetirizine and isopropylidene sedoheptuiosan. The pharmaceutical composition shows a good effect on treatment of acetyl cholinergic urticaria and is remarkably worthy of clinical popularization.