Biological tissue grinding device

Abstract

The invention discloses a biological tissue grinding device. The biological tissue grinding device comprises an airtight shell, a power unit, a transmission unit and an execution unit, wherein the airtight shell enables the whole grinding process to be conducted in an airtight space, so that biological tissue is prevented from being polluted, and the power unit, the transmission unit and the execution unit are arranged in the airtight shell; the power unit comprises a motor, the transmission unit comprises a main drive gear connected to the motor and at least two driven gears which are symmetrically arranged around the main drive gear and engaged with the main drive gear, and the execution unit comprises a sample cell and a plurality of grinding rods used for grinding the biological tissuein the sample cell; the sample cell is detachably connected to the airtight shell, the grinding rods are detachably connected to the driven gears, and a biological tissue sample can be simultaneouslygrinded by the multiple grinding rods through gear transmission; and the grinding efficiency is improved, the grinding rods are detachably connected to the driven gears, and mounting and dismountingof the grinding rods are facilitated.

Description

technical field [0001] The invention relates to the technical field of biomedicine, in particular to a biological tissue grinder. Background technique [0002] Biological tissue grinders are indispensable in the preparation of nucleic acids and proteins. At present, mortar-type grinders are commonly used in medical experiments. There are the following problems in using mortar-type grinders: 1) The mortar-type grinder is in operation. Exposure to the air during the grinding process is easy to pollute; 2) due to manual grinding, the grinding force is not easy to control, too long grinding time will cause the nucleic acid in the sample to decompose and deteriorate, while the grinding time is too short and there is insufficient grinding, the grinding effect 3) Manual operation is not only labor-intensive, but only one sample can be ground at a time, and the grinding efficiency is low. One experiment often requires several to more than ten mortars, which takes up a lot of space o...

AI Technical Summary

Problems solved by technology

[0002] Biological tissue grinders are indispensable in the preparation of nucleic acids and proteins. At present, mortar-type grinders are commonly used in medical experiments. There are the following problems in using mortar-type grinders: 1) The mortar-type grinder is in operation. Exposure to the air during the grinding process is easy to pollute; 2) due to manual grinding, the grinding force is not easy to control, too long grinding time will cause the nucleic acid in the sample to decompose and deteriorate, while the grinding time is too short and there is insufficient grinding, the grinding effect 3) Manual operation is not only labor-intensive, but only one sample can be ground at a time, and the grinding efficiency is low. One experiment often requires several to more than ten mortars, which takes up a lot of space on the operating table; 4) Grinding After the completion, the sample needs to be transferred to a centrifuge tube for separation and extraction, which may easily lead to sample loss and contamination during the transfer process; 5) In order to keep the low temperature in the mortar, liquid nitrogen needs to be added many times during the grinding process, which is time-consuming, laborious and prone to Dangerous; 6) The mortar is reused. The disinfection process needs to be soaked in disinfectant for 24 hours before high-temperature disinfection. The disinfection cycle is longer, which affects the progress of the experiment. If the cleaning and disinfection are not thorough, the next experimental specimen will be polluted

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