one based on wo 3 @au zno nanopillar biosensor with core-shell quantum dots and its preparation method

Abstract

The invention provides a ZnO nano column biosensor based on an Au@WO3 core-shell structure quantum dot and a preparation method of the ZnO nano column biosensor. The ZnO nano column biosensor comprises a conductive substrate, a ZnO nano column and an Au@WO3 core-shell structure quantum dot, wherein the ZnO nano column is prepared by growing a layer of a ZnO membrane on the conductive substrate andcorroding an expected pattern on the ZnO membrane; the Au@WO3 core-shell structure quantum dot is prepared by sputtering a WO3 membrane and an Au membrane in sequence on the surface of the ZnO nano column. Due to the Au@WO3 core-shell structure quantum dot, the properties of the ZnO nano column biosensor are improved, Au nanoparticles have efficient partial surface plasma enhancing effects, the WO3 membrane has an excellent quantum effect, and under coactions of the Au nanoparticles and the WO3 membrane, the properties of the ZnO nano column biosensor can be effectively improved; in addition,the Au@WO3 core-shell structure quantum dot provided by the invention is good in size controllability, good in quality uniformity, capable of meeting different requirements, applicable to industrialproduction requirements, wide in application range and applicable to other semiconductor biosensors and chemical sensors as well.

Description

technical field [0001] The invention relates to the technical field of biosensors, in particular to a ZnO nanocolumn biosensor based on WO3@Au core-shell structure quantum dots and a preparation method thereof. Background technique [0002] ZnO belongs to the third-generation n-type semiconductor material with a wide band gap. For biosensing applications, ZnO nanomaterials have many advantages: high specific surface area, good electrical conductivity, good biocompatibility, non-toxic, chemical stability, Environmentally friendly, etc., and has good stability in the air for long-term storage. The extremely rich morphology of ZnO nanomaterials also provides more flexible design ideas for its application in the field of sensors, making it very attractive for applications in the field of biochemical sensors. [0003] Biosensors generally achieve sensing by loading biological recognition units (such as enzymes, antibodies, DNA, etc.), but because these biological recognition uni...

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Problems solved by technology

[0003] Biosensors generally realize sensing by loading biological recognition units (such as enzymes, antibodies, DNA, etc.), but because these biological recognition units are expensive and perishable, storage and transportation are difficult, which greatly increases the cost.

The biosensor without biometric unit overcomes the above shortcomings, and is simple to prepare, low in cost, and long in life. Because ZnO has very good biocompatibility, and is non-toxic and pollution-free, it has an important position in the field of biosensors. Some biosensors based on ZnO nanocolumns / nanowires have become one of the mainstream development directions of biosensors. It can play an active role in environmental protection, medical treatment, biology, DNA detection, etc., but its performance is low. In order to improve ZnO The performance of based biosensors is usually enhanced by doping or using metal nanoparticles such as Au, Ru, etc., but the degree of performance improvement is not ideal.

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