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Dendrobium loddigesii extract and application thereof to preparation of cosmetics

A technology of Dendrobium candidum and cosmetics, applied in the fields of biomedicine and cosmetics, can solve the problems of whitening and anti-aging that are not mentioned or involved in Dendrobium candidum

Active Publication Date: 2018-05-18
KUNMING INST OF BOTANY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] None of the prior art relates to the whitening and anti-aging effects of Dendrobium meihua, nor does it mention that it is added to cosmetics as a functional additive

Method used

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  • Dendrobium loddigesii extract and application thereof to preparation of cosmetics
  • Dendrobium loddigesii extract and application thereof to preparation of cosmetics
  • Dendrobium loddigesii extract and application thereof to preparation of cosmetics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] The preparation of the extract of Dendrobium candidum: cut 10g of the stem of Dendrobium candidum, extract twice with 0-100% ethanol (w:v 1:6) under reflux, each time for 2h, combine the extracts and concentrate under reduced pressure to obtain 1.2g of extract, Mix the sample on the MCI column, elute with ethanol (0-100%), and concentrate under reduced pressure to obtain 0.8 g of the active site enrichment of Dendrobium candidum, which is detected by HPLC. The enrichment contains 4 of the following examples 4 Compounds ZDL-49, ZDL-23, ZDL-26, and ZDL-47, and the weight percentage of these four compounds accounted for 29.77% of the entire enrichment.

Embodiment 2

[0040]The preparation of Dendrobium candidum extract: 10g of Dendrobium candidum stem powder, 0-100% ethanol (w:v 1:6) reflux extraction twice, each time 2h, the combined extracts were concentrated under reduced pressure to obtain 1.3g of extract, After passing through the macroporous resin D101 column, ethanol (0-100%) was eluted, and concentrated under reduced pressure to obtain 0.9 g of the active site enrichment of Dendrobium candidum, which was detected by HPLC, and contained 4 of the following example 4 in the enrichment. There are three compounds ZDL-49, ZDL-23, ZDL-26, ZDL-47, and the weight percentage of these four compounds accounts for 20.54% of the whole enrichment.

Embodiment 3

[0042] Dried stems of Dendrobium candidum 1.0kg are crushed, refluxed with hot water for 3 times, dissolved in water under reduced pressure, and divided into 4 equal parts, 3 parts of which are degreased with petroleum ether; chloroform, n-butanol alcohol deproteinized, ethanol Remove polysaccharides, get water to extract skin care and whitening active parts, degreasing skin care and whitening active parts, deproteinized skin care and whitening active parts and depolysaccharide skin care and whitening active parts.

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Abstract

The invention discloses a dendrobium loddigesii extract and a monomeric compound therein as well as preparation methods and applications thereof to preparation of cosmetics. The dendrobium loddigesiiextract and the monomeric compound have whitening and anti-aging effects.

Description

technical field [0001] The invention belongs to the fields of biological medicine and cosmetics. In particular, it relates to an extract of Dendrobium meihua with whitening effect and monomer compounds therein. The Dendrobium meihua extract and its monomeric compounds have whitening and anti-aging effects, and can be used as functional additives in cosmetics. Background technique [0002] Dendrobium loddigesii Rolfe is a perennial herb of the genus Dendrobium in the Orchidaceae family (Orchidaceae), also known as Dendrobium ring grass, Dendrobium pink flower or Dendrobium earrings. The source is mainly distributed in Guizhou, Guangxi, Yunnan and Guangdong provinces, and also in Laos and Vietnam. Dendrobium candidum mainly contains chemical components such as Shu, phenanthrene, polyphenols, alkaloids, polysaccharides, etc., which have anti-platelet aggregation, inhibition of α-glucosidase, inhibition of Na+, K+-ATPase and inhibition of NO release. [0003] Dendrobium candi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61K8/49A61K8/37A61K8/34A61Q19/02A61Q19/08
CPCA61K8/347A61K8/375A61K8/498A61K2800/782A61Q19/02A61Q19/08C07C43/23
Inventor 杨柳胡江苗袁明焱邝梦婷李金玉周俊杨晓蓓颜莎
Owner KUNMING INST OF BOTANY - CHINESE ACAD OF SCI
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